Gene name:
SERPINF2 (AAP;PLI) ;
Protein name:
Alpha-2-antiplasmin (Alpha-2-AP) ;
Alternative:
Serpin F2 ;Alpha-2-plasmin inhibitor (Alpha-2-PI) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
The major targets of this inhibitor are plasmin and trypsin, but it also inactivates chymotrypsin.
Subcellular Location:
Secreted
Protein Attributes:
50:
MALLWGLLVL | SWSCLQGPCS | VFSPVSAMEP | LGRQLTSGPN | QEQVSPLTLL |
100:
KLGNQEPGGQ | TALKSPPGVC | SRDPTPEQTH | RLARAMMAFT | ADLFSLVAQT |
150:
STCPNLILSP | LSVALALSHL | ALGAQNHTLQ | RLQQVLHAGS | GPCLPHLLSR |
200:
LCQDLGPGAF | RLAARMYLQK | GFPIKEDFLE | QSEQLFGAKP | VSLTGKQEDD |
250:
LANINQWVKE | ATEGKIQEFL | SGLPEDTVLL | LLNAIHFQGF | WRNKFDPSLT |
300:
QRDSFHLDEQ | FTVPVEMMQA | RTYPLRWFLL | EQPEIQVAHF | PFKNNMSFVV |
350:
LVPTHFEWNV | SQVLANLSWD | TLHPPLVWER | PTKVRLPKLY | LKHQMDLVAT |
400:
LSQLGLQELF | QAPDLRGISE | QSLVVSGVQH | QSTLELSEVG | VEAAAATSIA |
450:
MSRMSLSSFS | VNRPFLFFIF | EDTTGLPLFV | GSVRNPNPSA | PRELKEQQDS |
491:
PGNKDFLQSL | KGFPRGDKLF | GPDLKLVPPM | EEDYPQFGSP | K
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Human
ELISA Kit for Human Alpha-2-AP
ELISA Kit for Human Alpha-2-AP
ELISA Kit for Human Alpha-2-AP
CLIA Kit for Human Alpha-2-AP
CLIA Kit for Human Alpha-2-AP
CLIA Kit for Human Alpha-2-AP
Polyclonal Antibody for Human Alpha-2-AP
Polyclonal Antibody for Human Alpha-2-AP
Polyclonal Antibody for Human Alpha-2-AP
Monoclonal Antibody for Human Alpha-2-AP
Monoclonal Antibody for Human Alpha-2-AP
Monoclonal Antibody for Human Alpha-2-AP
Protein for Human Alpha-2-AP
Protein for Human Alpha-2-AP
Protein for Human Alpha-2-AP
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
A Siennicka, M Zuchowski, M Kaczmarczyk, et al.
[2].
Zakrzewski M, Zakrzewska E, Kiciński P, et al.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Liver .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT VAL-2
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 4-491 (ISOFORM 1)
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 28-58
tissue :
Plasma .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 28-52
tissue :
Plasma .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 40-491
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 40-43
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 218-491
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 481-491;SULFATION AT TYR-484
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REACTIVE SITES
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISULFIDE BOND
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CLEAVAGE BY SOLUBLE FAP FORM;CLEAVAGE SITE
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN MEMBRANE-ANCHORED SERINE PROTEASE TMPRSS7 INHIBITION;HETERODIMER WITH TMPRSS7
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-126; ASN-295 AND ASN-309
tissue :
Plasma .
19.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CLEAVAGE BY PLASMA MEMBRANE AND SOLUBLE FAP FORMS;CLEAVAGE SITE
20.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT APLID GLU-176 DEL
21.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT APLID MET-411;VARIANTS VAL-27; TRP-33 AND LYS-434