Gene name:
ADAM12 (UNQ346/PRO545;MLTN) ;
Protein name:
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) ;
Alternative:
Meltrin-alpha ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with alpha-actinin-2 and with syndecans (By similarity). Interacts with SH3PXD2A. Interacts with FST3. Interacts with GNB2L1/RACK1; the interaction is required for PKC-dependent translocation of ADAM12 to the cell membrane.
Function:
Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.
Subcellular Location:
Isoform 4
Secreted
Protein Attributes:
50:
MAARPLPVSP | ARALLLALAG | ALLAPCEARG | VSLWNQGRAD | EVVSASVGSG |
100:
DLWIPVKSFD | SKNHPEVLNI | RLQRESKELI | INLERNEGLI | ASSFTETHYL |
150:
QDGTDVSLAR | NYTVILGHCY | YHGHVRGYSD | SAVSLSTCSG | LRGLIVFENE |
200:
SYVLEPMKSA | TNRYKLFPAK | KLKSVRGSCG | SHHNTPNLAA | KNVFPPPSQT |
250:
WARRHKRETL | KATKYVELVI | VADNREFQRQ | GKDLEKVKQR | LIEIANHVDK |
300:
FYRPLNIRIV | LVGVEVWNDM | DKCSVSQDPF | TSLHEFLDWR | KMKLLPRKSH |
350:
DNAQLVSGVY | FQGTTIGMAP | IMSMCTADQS | GGIVMDHSDN | PLGAAVTLAH |
400:
ELGHNFGMNH | DTLDRGCSCQ | MAVEKGGCIM | NASTGYPFPM | VFSSCSRKDL |
450:
ETSLEKGMGV | CLFNLPEVRE | SFGGQKCGNR | FVEEGEECDC | GEPEECMNRC |
500:
CNATTCTLKP | DAVCAHGLCC | EDCQLKPAGT | ACRDSSNSCD | LPEFCTGASP |
550:
HCPANVYLHD | GHSCQDVDGY | CYNGICQTHE | QQCVTLWGPG | AKPAPGICFE |
600:
RVNSAGDPYG | NCGKVSKSSF | AKCEMRDAKC | GKIQCQGGAS | RPVIGTNAVS |
650:
IETNIPLQQG | GRILCRGTHV | YLGDDMPDPG | LVLAGTKCAD | GKICLNRQCQ |
700:
NISVFGVHEC | AMQCHGRGVC | NNRKNCHCEA | HWAPPFCDKF | GFGGSTDSGP |
750:
IRQADNQGLT | IGILVTILCL | LAAGFVVYLK | RKTLIRLLFT | NKKTTIEKLR |
800:
CVRPSRPPRG | FQPCQAHLGH | LGKGLMRKPP | DSYPPKDNPR | RLLQCQNVDI |
850:
SRPLNGLNVP | QPQSTQRVLP | PLHRAPRAPS | VPARPLPAKP | ALRQAQGTCK |
900:
PNPPQKPLPA | DPLARTTRLT | HALARTPGQW | ETGLRLAPLR | PAPQYPHQVP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human ADAM 12
ELISA Kit for Human ADAM 12
CLIA Kit for Human ADAM 12
CLIA Kit for Human ADAM 12
Polyclonal Antibody for Human ADAM 12
Polyclonal Antibody for Human ADAM 12
Monoclonal Antibody for Human ADAM 12
Monoclonal Antibody for Human ADAM 12
Protein for Human ADAM 12
Protein for Human ADAM 12
R&D Technical Data
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Precision
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Recovery
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Linearity
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