Adam12 ELISA Kit for Mouse(Mus musculus) | EIAab.comAdam12 ELISA Kit for Mouse(Mus musculus)

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Adam12 (Gene name),

Disintegrin and metalloproteinase domain-containing protein 12 (Protein name ), ADA12_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Adam12(Mltna);

Protein name:

Disintegrin and metalloproteinase domain-containing protein 12(ADAM 12);

Alternative:

Meltrin-alpha;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with alpha-actinin-2 and with syndecans. Interacts with SH3PXD2A. Interacts with FST3. Interacts with GNB2L1/RACK1; the interaction is required for PKC-dependent translocation of ADAM12 to the cell membrane.

Function:

Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

903

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

903:

YIK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:11489

String:

Q61824

Pfam:

PF08516

SMR:

Q61824

UniGene:

Mm.439714

Uniprot:

Q61824

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ELISA Kit for Mouse ADAM 12

Cat.:

E14640h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Mouse ADAM 12

Cat.:

E14640m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse ADAM 12

Cat.:

U14640h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse ADAM 12

Cat.:

U14640m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse ADAM 12

Monoclonal Antibody for Mouse ADAM 12

Protein for Mouse ADAM 12

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A metalloprotease-disintegrin participating in myoblast fusion."
Yagami-Hiromasa T. , Sato T. , Kurisaki T. , Kamijo K. , Nabeshima Y. , Fujisawa-Sehara A.
Nature377:652-656(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Embryonic fibroblast.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"Spatially- and temporally-restricted expression of meltrin alpha (ADAM12) and beta (ADAM19) in mouse embryo."
Kurisaki T. , Masuda A. , Osumi N. , Nabeshima Y. , Fujisawa-Sehara A.
Mech. Dev.73:211-215(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
4.

"Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha-actinin-2, is required for myoblast fusion."
Galliano M.-F. , Huet C. , Frygelius J. , Polgren A. , Wewer U.M. , Engvall E.
J. Biol. Chem.275:13933-13939(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ALPHA-ACTININ-2
5.

"Meltrin alpha cytoplasmic domain interacts with SH3 domains of Src and Grb2 and is phosphorylated by v-Src."
Suzuki A. , Kadota N. , Hara T. , Nakagami Y. , Izumi T. , Takenawa T. , Sabe H. , Endo T.
Oncogene19:5842-5850(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-901

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