Protein name:
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) ;
Alternative:
TNF-alpha-converting enzyme ;TNF-alpha convertase ;
CD:
CD156b ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Interacts with MAD2L1 and MUC1.
Function:
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity). Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MLREQFSFDI | AEEASKVCLA | HLFTYQDFDM | GTLGLAYVGS | PRANSHGGVC |
100:
PKAYYSPIGK | KNIYLNSGLT | STKNYGKTIL | TKEADLVTTH | ELGHNFGAEH |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Mouse
Rat
ELISA Kit for Pig ADAM 17
ELISA Kit for Pig ADAM 17
ELISA Kit for Pig ADAM 17
ELISA Kit for Pig ADAM 17
Polyclonal Antibody for Pig ADAM 17
Polyclonal Antibody for Pig ADAM 17
Polyclonal Antibody for Pig ADAM 17
Polyclonal Antibody for Pig ADAM 17
Monoclonal Antibody for Pig ADAM 17
Monoclonal Antibody for Pig ADAM 17
Monoclonal Antibody for Pig ADAM 17
Monoclonal Antibody for Pig ADAM 17
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]