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Index > Protein center > ADAM28(Gene name) > Human
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  • ADAM28 (Gene name),
  • Disintegrin and metalloproteinase domain-containing protein 28 (Protein name ),  ADA28_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ADAM28(ADAM23;MDCL);
    Protein name:
    Disintegrin and metalloproteinase domain-containing protein 28(ADAM 28);
    Alternative:
    Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L(MDC-L);Epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II(eMDC II);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.
    Subcellular Location:
    Isoform 2 Secreted
    Protein Attributes:
    Sequence length:
    775
    Sequence:
    50:
    MLQGLLPVSL | LLSVAVSAIK | ELPGVKKYEV | VYPIRLHPLH | KREAKEPEQQ | 
    100:
    EQFETELKYK | MTINGKIAVL | YLKKNKNLLA | PGYTETYYNS | TGKEITTSPQ | 
    150:
    IMDDCYYQGH | ILNEKVSDAS | ISTCRGLRGY | FSQGDQRYFI | EPLSPIHRDG | 
    200:
    QEHALFKYNP | DEKNYDSTCG | MDGVLWAHDL | QQNIALPATK | LVKLKDRKVQ | 
    250:
    EHEKYIEYYL | VLDNGEFKRY | NENQDEIRKR | VFEMANYVNM | LYKKLNTHVA | 
    300:
    LVGMEIWTDK | DKIKITPNAS | FTLENFSKWR | GSVLSRRKRH | DIAQLITATE | 
    350:
    LAGTTVGLAF | MSTMCSPYSV | GVVQDHSDNL | LRVAGTMAHE | MGHNFGMFHD | 
    400:
    DYSCKCPSTI | CVMDKALSFY | IPTDFSSCSR | LSYDKFFEDK | LSNCLFNAPL | 
    450:
    PTDIISTPIC | GNQLVEMGED | CDCGTSEECT | NICCDAKTCK | IKATFQCALG | 
    500:
    ECCEKCQFKK | AGMVCRPAKD | ECDLPEMCNG | KSGNCPDDRF | QVNGFPCHHG | 
    550:
    KGHCLMGTCP | TLQEQCTELW | GPGTEVADKS | CYNRNEGGSK | YGYCRRVDDT | 
    600:
    LIPCKANDTM | CGKLFCQGGS | DNLPWKGRIV | TFLTCKTFDP | EDTSQEIGMV | 
    650:
    ANGTKCGDNK | VCINAECVDI | EKAYKSTNCS | SKCKGHAVCD | HELQCQCEEG | 
    700:
    WIPPDCDDSS | VVFHFSIVVG | VLFPMAVIFV | VVAMVIRHQS | SREKQKKDQR | 
    750:
    PLSTTGTRPH | KQKRKPQMVK | AVQPQEMSQM | KPHVYDLPVE | GNEPPASFHK | 
    775:
    DTNALPPTVF | KDNPVSTPKD | SNPKA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    MIM:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human ADAM 28
    Cat.:
    E14606h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human ADAM 28
    Cat.:
    E14606m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human ADAM 28
    Cat.:
    U14606m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human ADAM 28
    Cat.:
    U14606h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human ADAM 28
    Polyclonal Antibody for Human ADAM 28
    Monoclonal Antibody for Human ADAM 28
    Monoclonal Antibody for Human ADAM 28
    Protein for Human ADAM 28
    Protein for Human ADAM 28

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "MDC-L, a novel metalloprotease disintegrin cysteine-rich protein family member expressed by human lymphocytes."
      Roberts C.M. , Tani P.H. , Bridges L.C. , Laszik Z. , Bowditch R.D.
      J. Biol. Chem.274:29251-29259(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);VARIANT MET-765
      tissue: Lymph node.
    2. 2.
      "Identification, sequence analysis and expression of transcripts encoding a putative metalloproteinase, eMDC II, in human and macaque epididymis."
      Jury J.A. , Perry A.C. , Hall L.
      Mol. Hum. Reprod.5:1127-1134(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-765
      tissue: Epididymis.
    3. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT MET-765
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT MET-765
      tissue: Brain.
    5. 6.
      "Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma."
      Wei X. , Moncada-Pazos A. , Cal S. , Soria-Valles C. , Gartner J. , Rudloff U. , Lin J.C. , Rosenberg S.A. , Lopez-Otin C. , Samuels Y.
      Hum. Mutat.32:E2148-E2175(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GLU-65; GLU-134; GLU-450; PHE-482 AND ASP-502
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