Protein name:
Disintegrin and metalloproteinase domain-containing protein 2 (ADAM 2) ;
Alternative:
Fertilin subunit beta ;Cancer/testis antigen 15 (CT15) ;PH30-beta ;PH-30 (PH30) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MWRVLFLLSG | LGGLRMDSNF | DSLPVQITVP | EKIRSIIKEG | IESQASYKIV |
100:
IEGKPYTVNL | MQKNFLPHNF | RVYSYSGTGI | MKPLDQDFQN | FCHYQGYIEG |
150:
YPKSVVMVST | CTGLRGVLQF | ENVSYGIEPL | ESSVGFEHVI | YQVKHKKADV |
200:
SLYNEKDIES | RDLSFKLQSV | EPQQDFAKYI | EMHVIVEKQL | YNHMGSDTTV |
250:
VAQKVFQLIG | LTNAIFVSFN | ITIILSSLEL | WIDENKIATT | GEANELLHTF |
300:
LRWKTSYLVL | RPHDVAFLLV | YREKSNYVGA | TFQGKMCDAN | YAGGVVLHPR |
350:
TISLESLAVI | LAQLLSLSMG | ITYDDINKCQ | CSGAVCIMNP | EAIHFSGVKI |
400:
FSNCSFEDFA | HFISKQKSQC | LHNQPRLDPF | FKQQAVCGNA | KLEAGEECDC |
450:
GTEQDCALIG | ETCCDIATCR | FKAGSNCAEG | PCCENCLFMS | KERMCRPSFE |
500:
ECDLPEYCNG | SSASCPENHY | VQTGHPCGLN | QWICIDGVCM | SGDKQCTDTF |
550:
GKEVEFGPSE | CYSHLNSKTD | VSGNCGISDS | GYTQCEADNL | QCGKLICKYV |
600:
GKFLLQIPRA | TIIYANISGH | LCIAVEFASD | HADSQKMWIK | DGTSCGSNKV |
650:
CRNQRCVSSS | YLGYDCTTDK | CNDRGVCNNK | KHCHCSASYL | PPDCSVQSDL |
700:
WPGGSIDSGN | FPPVAIPARL | PERRYIENIY | HSKPMRWPFF | LFIPFFIIFC |
735:
VLIAIMVKVN | FQRKKWRTED | YSSDEQPESE | SEPKG
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Rabbit
Mouse
Rat
ELISA Kit for Human ADAM 2
ELISA Kit for Human ADAM 2
ELISA Kit for Human ADAM 2
ELISA Kit for Human ADAM 2
ELISA Kit for Human ADAM 2
CLIA Kit for Human ADAM 2
CLIA Kit for Human ADAM 2
CLIA Kit for Human ADAM 2
CLIA Kit for Human ADAM 2
CLIA Kit for Human ADAM 2
Polyclonal Antibody for Human ADAM 2
Polyclonal Antibody for Human ADAM 2
Polyclonal Antibody for Human ADAM 2
Polyclonal Antibody for Human ADAM 2
Polyclonal Antibody for Human ADAM 2
Monoclonal Antibody for Human ADAM 2
Monoclonal Antibody for Human ADAM 2
Monoclonal Antibody for Human ADAM 2
Monoclonal Antibody for Human ADAM 2
Monoclonal Antibody for Human ADAM 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Testis .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Testis .
4.
"Nucleotide sequence of the human fertilin beta transcript."
Hall L.
,
Frayne J.
Submitted (1999-04) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Testis .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Testis .