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Index > Protein center > ALDH1A1(Gene name) > Human
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  • ALDH1A1 (Gene name),
  • Retinal dehydrogenase 1 (Protein name ),  AL1A1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (1)
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  • Gene name:
    ALDH1A1(ALDC;ALDH1;PUMB1);
    Protein name:
    Retinal dehydrogenase 1(RALDH 1;RalDH1);
    Alternative:
    Aldehyde dehydrogenase, cytosolic;Aldehyde dehydrogenase family 1 member A1;ALDH-E1;ALHDII;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    501
    Sequence:
    50:
    MSSSGTPDLP | VLLTDLKIQY | TKIFINNEWH | DSVSGKKFPV | FNPATEEELC | 
    100:
    QVEEGDKEDV | DKAVKAARQA | FQIGSPWRTM | DASERGRLLY | KLADLIERDR | 
    150:
    LLLATMESMN | GGKLYSNAYL | NDLAGCIKTL | RYCAGWADKI | QGRTIPIDGN | 
    200:
    FFTYTRHEPI | GVCGQIIPWN | FPLVMLIWKI | GPALSCGNTV | VVKPAEQTPL | 
    250:
    TALHVASLIK | EAGFPPGVVN | IVPGYGPTAG | AAISSHMDID | KVAFTGSTEV | 
    300:
    GKLIKEAAGK | SNLKRVTLEL | GGKSPCIVLA | DADLDNAVEF | AHHGVFYHQG | 
    350:
    QCCIAASRIF | VEESIYDEFV | RRSVERAKKY | ILGNPLTPGV | TQGPQIDKEQ | 
    400:
    YDKILDLIES | GKKEGAKLEC | GGGPWGNKGY | FVQPTVFSNV | TDEMRIAKEE | 
    450:
    IFGPVQQIMK | FKSLDDVIKR | ANNTFYGLSA | GVFTKDIDKA | ITISSALQAG | 
    500:
    TVWVNCYGVV | SAQCPFGGFK | MSGNGRELGE | YGFHEYTEVK | TVTVKISQKN | 
    501:
    S
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    Pfam:
    SMR:
    UniGene:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human RALDH 1
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    ELISA Kit for Human RALDH 1
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    ELISA Kit for Human RALDH 1
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    ELISA Kit for Human RALDH 1
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    ELISA Kit for Human RALDH 1
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    E0680b
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    ELISA Kit for Human RALDH 1
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    E0680c
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    96T
    CLIA Kit for Human RALDH 1
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    CLIA Kit for Human RALDH 1
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    CLIA Kit for Human RALDH 1
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    CLIA Kit for Human RALDH 1
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    U0680h
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    Packing:
    96T
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    CLIA Kit for Human RALDH 1
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    U0680c
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    96T
    CLIA Kit for Human RALDH 1
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    U0680b
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human RALDH 1
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    P0680Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human RALDH 1
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    P0680Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human RALDH 1
    Polyclonal Antibody for Human RALDH 1
    Polyclonal Antibody for Human RALDH 1
    Polyclonal Antibody for Human RALDH 1
    Cat.:
    P0680Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human RALDH 1
    Monoclonal Antibody for Human RALDH 1
    Monoclonal Antibody for Human RALDH 1
    Monoclonal Antibody for Human RALDH 1
    Monoclonal Antibody for Human RALDH 1
    Monoclonal Antibody for Human RALDH 1
    Protein for Human RALDH 1
    Protein for Human RALDH 1
    Protein for Human RALDH 1
    Protein for Human RALDH 1
    Cat.:
    R0680h
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Human RALDH 1
    Protein for Human RALDH 1

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    References
    1. 1.
      "Genomic structure of the human cytosolic aldehyde dehydrogenase gene."
      Hsu L.C. , Chang W.-C. , Yoshida A.
      Genomics5:857-865(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Cloning and expression of the full-length cDNAs encoding human liver class 1 and class 2 aldehyde dehydrogenase."
      Zheng C.F. , Wang T.T. , Weiner H.
      Alcohol. Clin. Exp. Res.17:828-831(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-121
      tissue: Liver.
    3. 3.
      "Cloning and expression of aldehyde dehydrogenase 1 (ALDH1A1) from human lens cDNA library."
      Ramana K.V. , Xiao T. , Ansari N.H.
      Submitted (2003-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Lens.
    4. 4.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      NIEHS SNPs program
      Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT PHE-177
    6. 6.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Colon.
    9. 9.
      "Biological role of human cytosolic aldehyde dehydrogenase 1: hormonal response, retinal oxidation and implication in testicular feminization."
      Yoshida A. , Hsu L.C. , Yanagawa Y.
      Adv. Exp. Med. Biol.328:37-44(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-6
    10. 10.
      "Aldehyde dehydrogenase from human liver. Primary structure of the cytoplasmic isoenzyme."
      Hempel J. , von Bahr-Lindstroem H. , Joernvall H.
      Eur. J. Biochem.141:21-35(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-501;ACETYLATION AT SER-2
      tissue: Liver.
    11. 11.
      "Molecular abnormality and cDNA cloning of human aldehyde dehydrogenases."
      Yoshida A. , Ikawa M. , Hsu L.C. , Tani K.
      Alcohol2:103-106(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 162-501
    12. 12.
      "Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2."
      Hsu L.C. , Tani K. , Fujiyoshi T. , Kurachi K. , Yoshida A.
      Proc. Natl. Acad. Sci. U.S.A.82:3771-3775(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 162-501
      tissue: Liver.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 266-273;ACTIVE SITES GLU-269 AND CYS-303;NAD-BINDING SITE CYS-456
    14. 14.
      "Aldehyde dehydrogenase from human erythrocytes: structural relationship to the liver cytosolic isozyme."
      Agarwal D.P. , Cohn P. , Goedde H.W. , Hempel J.
      Enzyme42:47-52(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
      tissue: Erythrocyte.
    15. 15.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-91; LYS-128; LYS-252; LYS-353; LYS-367; LYS-410; LYS-419; LYS-435 AND LYS-495;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    17. 17.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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