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Index > Protein center > AQP3(Gene name) > Human
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  • AQP3 (Gene name),
  • Aquaporin-3 (Protein name ),  AQP3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AQP3;
    Protein name:
    Aquaporin-3(AQP-3);
    Alternative:
    Aquaglyceroporin-3;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
    Subcellular Location:
    Basolateral cell membrane Multi-pass membrane protein In collecting ducts of kidney.
    Protein Attributes:
    Sequence length:
    292
    Sequence:
    50:
    MGRQKELVSR | CGEMLHIRYR | LLRQALAECL | GTLILVMFGC | GSVAQVVLSR | 
    100:
    GTHGGFLTIN | LAFGFAVTLG | ILIAGQVSGA | HLNPAVTFAM | CFLAREPWIK | 
    150:
    LPIYTLAQTL | GAFLGAGIVF | GLYYDAIWHF | ADNQLFVSGP | NGTAGIFATY | 
    200:
    PSGHLDMING | FFDQFIGTAS | LIVCVLAIVD | PYNNPVPRGL | EAFTVGLVVL | 
    250:
    VIGTSMGFNS | GYAVNPARDF | GPRLFTALAG | WGSAVFTTGQ | HWWWVPIVSP | 
    292:
    LLGSIAGVFV | YQLMIGCHLE | QPPPSNEEEN | VKLAHVKHKE | QI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    UniGene:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human AQP-3
    Cat.:
    E0581m
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    96T
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    ELISA Kit for Human AQP-3
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    E0581b
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    96T
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    ELISA Kit for Human AQP-3
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    E0581p
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    96T
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    ELISA Kit for Human AQP-3
    Cat.:
    E0581r
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    96T
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    ELISA Kit for Human AQP-3
    Cat.:
    E0581h
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    96T
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    CLIA Kit for Human AQP-3
    Cat.:
    U0581h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human AQP-3
    Cat.:
    U0581r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human AQP-3
    Cat.:
    U0581p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human AQP-3
    Cat.:
    U0581m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human AQP-3
    Cat.:
    U0581b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human AQP-3
    Cat.:
    P0581Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human AQP-3
    Polyclonal Antibody for Human AQP-3
    Cat.:
    P0581Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human AQP-3
    Cat.:
    P0581Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human AQP-3
    Monoclonal Antibody for Human AQP-3
    Monoclonal Antibody for Human AQP-3
    Monoclonal Antibody for Human AQP-3
    Monoclonal Antibody for Human AQP-3
    Monoclonal Antibody for Human AQP-3
    Protein for Human AQP-3
    Protein for Human AQP-3
    Protein for Human AQP-3
    Protein for Human AQP-3
    Protein for Human AQP-3

    R&D Technical Data
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    Linearity
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    References
    1. 1.
      "Structure and chromosomal localization of a human water channel (AQP3) gene."
      Ishibashi K. , Sasaki S. , Saito F. , Ikeuchi T. , Marumo F.
      Genomics27:352-354(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Kidney.
    2. 2.
      Ishibashi K.
      Submitted (1996-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 91; 96 AND 186
    3. 3.
      "AQP3 deficiency in humans and the molecular basis of a novel blood group system, GIL."
      Roudier N. , Ripoche P. , Gane P. , Le Pennec P.Y. , Daniels G. , Cartron J.-P. , Bailly P.
      J. Biol. Chem.277:45854-45859(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);GIL BLOOD GROUP SYSTEM
      tissue: Blood.
    4. 4.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Halleck A. , Ebert L. , Mkoundinya M. , Schick M. , Eisenstein S. , Neubert P. , Kstrang K. , Schatten R. , Shen B. , Henze S. , Mar W. , Korn B. , Zuo D. , Hu Y. , LaBaer J.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Esophagus.
      tissue: Trachea.
    7. 7.
      SeattleSNPs variation discovery resource
      Submitted (2005-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT MET-43
    8. 8.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Lung.
    11. 11.
      "Regulation of aquaporin 3 expression by magnesium ion."
      Okahira M. , Kubota M. , Iguchi K. , Usui S. , Hirano K.
      Eur. J. Pharmacol.588:26-32(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
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