Protein name:
Aquaporin-3 (AQP-3) ;
Alternative:
Aquaglyceroporin-3 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
Subcellular Location:
Basolateral cell membrane
Multi-pass membrane protein
In collecting ducts of kidney.
Protein Attributes:
50:
MGRQKELVSR | CGEMLHIRYR | LLRQALAECL | GTLILVMFGC | GSVAQVVLSR |
100:
GTHGGFLTIN | LAFGFAVTLG | ILIAGQVSGA | HLNPAVTFAM | CFLAREPWIK |
150:
LPIYTLAQTL | GAFLGAGIVF | GLYYDAIWHF | ADNQLFVSGP | NGTAGIFATY |
200:
PSGHLDMING | FFDQFIGTAS | LIVCVLAIVD | PYNNPVPRGL | EAFTVGLVVL |
250:
VIGTSMGFNS | GYAVNPARDF | GPRLFTALAG | WGSAVFTTGQ | HWWWVPIVSP |
292:
LLGSIAGVFV | YQLMIGCHLE | QPPPSNEEEN | VKLAHVKHKE | QI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Bovine
Pig
Rat
Human
ELISA Kit for Human AQP-3
ELISA Kit for Human AQP-3
ELISA Kit for Human AQP-3
ELISA Kit for Human AQP-3
ELISA Kit for Human AQP-3
Polyclonal Antibody for Human AQP-3
Polyclonal Antibody for Human AQP-3
Polyclonal Antibody for Human AQP-3
Polyclonal Antibody for Human AQP-3
Polyclonal Antibody for Human AQP-3
Monoclonal Antibody for Human AQP-3
Monoclonal Antibody for Human AQP-3
Monoclonal Antibody for Human AQP-3
Monoclonal Antibody for Human AQP-3
Monoclonal Antibody for Human AQP-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Lung .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INDUCTION