Protein name:
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAM-TS 1;ADAM-TS1;ADAMTS-1) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity (By similarity). Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MQPKVPLGSR | KQKPCSDMGD | VQRAARSRGS | LSAHMLLLLL | ASITMLLCAR |
100:
GAHGRPTEED | EELVLPSLER | APGHDSTTTR | LRLDAFGQQL | HLKLQPDSGF |
150:
LAPGFTLQTV | GRSPGSEAQH | LDPTGDLAHC | FYSGTVNGDP | GSAAALSLCE |
200:
GVRGAFYLQG | EEFFIQPAPG | VATERLAPAV | PEEESSARPQ | FHILRRRRRG |
250:
SGGAKCGVMD | DETLPTSDSR | PESQNTRNQW | PVRDPTPQDA | GKPSGPGSIR |
300:
KKRFVSSPRY | VETMLVADQS | MADFHGSGLK | HYLLTLFSVA | ARFYKHPSIR |
350:
NSISLVVVKI | LVIYEEQKGP | EVTSNAALTL | RNFCSWQKQH | NSPSDRDPEH |
400:
YDTAILFTRQ | DLCGSHTCDT | LGMADVGTVC | DPSRSCSVIE | DDGLQAAFTT |
450:
AHELGHVFNM | PHDDAKHCAS | LNGVSGDSHL | MASMLSSLDH | SQPWSPCSAY |
500:
MVTSFLDNGH | GECLMDKPQN | PIKLPSDLPG | TLYDANRQCQ | FTFGEESKHC |
550:
PDAASTCTTL | WCTGTSGGLL | VCQTKHFPWA | DGTSCGEGKW | CVSGKCVNKT |
600:
DMKHFATPVH | GSWGPWGPWG | DCSRTCGGGV | QYTMRECDNP | VPKNGGKYCE |
650:
GKRVRYRSCN | IEDCPDNNGK | TFREEQCEAH | NEFSKASFGN | EPTVEWTPKY |
700:
AGVSPKDRCK | LTCEAKGIGY | FFVLQPKVVD | GTPCSPDSTS | VCVQGQCVKA |
750:
GCDRIIDSKK | KFDKCGVCGG | NGSTCKKMSG | IVTSTRPGYH | DIVTIPAGAT |
800:
NIEVKHRNQR | GSRNNGSFLA | IRAADGTYIL | NGNFTLSTLE | QDLTYKGTVL |
850:
RYSGSSAALE | RIRSFSPLKE | PLTIQVLMVG | HALRPKIKFT | YFMKKKTESF |
900:
NAIPTFSEWV | IEEWGECSKT | CGSGWQRRVV | QCRDINGHPA | SECAKEVKPA |
950:
STRPCADLPC | PHWQVGDWSP | CSKTCGKGYK | KRTLKCVSHD | GGVLSNESCD |
968:
PLKKPKHYID | FCTLTQCS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Mouse ADAM-TS 1
ELISA Kit for Mouse ADAM-TS 1
ELISA Kit for Mouse ADAM-TS 1
CLIA Kit for Mouse ADAM-TS 1
CLIA Kit for Mouse ADAM-TS 1
CLIA Kit for Mouse ADAM-TS 1
Polyclonal Antibody for Mouse ADAM-TS 1
Polyclonal Antibody for Mouse ADAM-TS 1
Polyclonal Antibody for Mouse ADAM-TS 1
Monoclonal Antibody for Mouse ADAM-TS 1
Monoclonal Antibody for Mouse ADAM-TS 1
Monoclonal Antibody for Mouse ADAM-TS 1
Protein for Mouse ADAM-TS 1
Protein for Mouse ADAM-TS 1
Protein for Mouse ADAM-TS 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
129/SvJ .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
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Goodstadt L.
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Zody M.C.
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Goldstein S.
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She X.
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Bult C.J.
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more...
PLoS Biol.7:E1000112-E1000112(2009)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Limb .
tissue :
Mammary gland .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION;MUTAGENESIS OF GLU-403
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INDUCTION