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Index > Protein center > Adamts1(Gene name) > Mouse
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  • Adamts1 (Gene name),
  • A disintegrin and metalloproteinase with thrombospondin motifs 1 (Protein name ),  ATS1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Adamts1;
    Protein name:
    A disintegrin and metalloproteinase with thrombospondin motifs 1(ADAM-TS 1;ADAM-TS1;ADAMTS-1);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Function:
    Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity (By similarity). Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    968
    Sequence:
    50:
    MQPKVPLGSR | KQKPCSDMGD | VQRAARSRGS | LSAHMLLLLL | ASITMLLCAR | 
    100:
    GAHGRPTEED | EELVLPSLER | APGHDSTTTR | LRLDAFGQQL | HLKLQPDSGF | 
    150:
    LAPGFTLQTV | GRSPGSEAQH | LDPTGDLAHC | FYSGTVNGDP | GSAAALSLCE | 
    200:
    GVRGAFYLQG | EEFFIQPAPG | VATERLAPAV | PEEESSARPQ | FHILRRRRRG | 
    250:
    SGGAKCGVMD | DETLPTSDSR | PESQNTRNQW | PVRDPTPQDA | GKPSGPGSIR | 
    300:
    KKRFVSSPRY | VETMLVADQS | MADFHGSGLK | HYLLTLFSVA | ARFYKHPSIR | 
    350:
    NSISLVVVKI | LVIYEEQKGP | EVTSNAALTL | RNFCSWQKQH | NSPSDRDPEH | 
    400:
    YDTAILFTRQ | DLCGSHTCDT | LGMADVGTVC | DPSRSCSVIE | DDGLQAAFTT | 
    450:
    AHELGHVFNM | PHDDAKHCAS | LNGVSGDSHL | MASMLSSLDH | SQPWSPCSAY | 
    500:
    MVTSFLDNGH | GECLMDKPQN | PIKLPSDLPG | TLYDANRQCQ | FTFGEESKHC | 
    550:
    PDAASTCTTL | WCTGTSGGLL | VCQTKHFPWA | DGTSCGEGKW | CVSGKCVNKT | 
    600:
    DMKHFATPVH | GSWGPWGPWG | DCSRTCGGGV | QYTMRECDNP | VPKNGGKYCE | 
    650:
    GKRVRYRSCN | IEDCPDNNGK | TFREEQCEAH | NEFSKASFGN | EPTVEWTPKY | 
    700:
    AGVSPKDRCK | LTCEAKGIGY | FFVLQPKVVD | GTPCSPDSTS | VCVQGQCVKA | 
    750:
    GCDRIIDSKK | KFDKCGVCGG | NGSTCKKMSG | IVTSTRPGYH | DIVTIPAGAT | 
    800:
    NIEVKHRNQR | GSRNNGSFLA | IRAADGTYIL | NGNFTLSTLE | QDLTYKGTVL | 
    850:
    RYSGSSAALE | RIRSFSPLKE | PLTIQVLMVG | HALRPKIKFT | YFMKKKTESF | 
    900:
    NAIPTFSEWV | IEEWGECSKT | CGSGWQRRVV | QCRDINGHPA | SECAKEVKPA | 
    950:
    STRPCADLPC | PHWQVGDWSP | CSKTCGKGYK | KRTLKCVSHD | GGVLSNESCD | 
    968:
    PLKKPKHYID | FCTLTQCS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ADAM-TS 1
    Cat.:
    E1973h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse ADAM-TS 1
    Cat.:
    E1973m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse ADAM-TS 1
    Cat.:
    E1973r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ADAM-TS 1
    Cat.:
    U1973h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ADAM-TS 1
    Cat.:
    U1973r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ADAM-TS 1
    Cat.:
    U1973m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse ADAM-TS 1
    Cat.:
    P1973Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ADAM-TS 1
    Cat.:
    P1973Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ADAM-TS 1
    Cat.:
    P1973Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse ADAM-TS 1
    Monoclonal Antibody for Mouse ADAM-TS 1
    Monoclonal Antibody for Mouse ADAM-TS 1
    Protein for Mouse ADAM-TS 1
    Protein for Mouse ADAM-TS 1
    Protein for Mouse ADAM-TS 1
    Cat.:
    R1973h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The exon/intron organization and chromosomal mapping of the mouse ADAMTS-1 gene encoding an ADAM family protein with TSP motifs."
      Kuno K. , Lizasa H. , Ohno S. , Matsushima K.
      Genomics46:466-471(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/SvJ.
    2. 2.
      "Molecular cloning of a gene encoding a new type of metalloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene."
      Kuno K. , Kanada N. , Nakashima E. , Fujiki F. , Ichimura F. , Matsushima K.
      J. Biol. Chem.272:556-562(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Limb.
      tissue: Mammary gland.
    5. 5.
      "ADAMTS-1 is an active metalloproteinase associated with the extracellular matrix."
      Kuno K. , Terashima Y. , Matsushima K.
      J. Biol. Chem.274:18821-18826(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION;MUTAGENESIS OF GLU-403
    6. 6.
      "ADAMTS-1 cleaves a cartilage proteoglycan, aggrecan."
      Kuno K. , Okada Y. , Kawashima H. , Nakamura H. , Miyasaka M. , Ohno H. , Matsushima K.
      FEBS Lett.478:241-245(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases."
      Robker R.L. , Russell D.L. , Espey L.L. , Lydon J.P. , O'Malley B.W. , Richards J.S.
      Proc. Natl. Acad. Sci. U.S.A.97:4689-4694(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
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