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Index > Protein center > ADAMTS4(Gene name) > Bovine
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  • ADAMTS4 (Gene name),
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (Protein name ),  ATS4_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ADAMTS4;
    Protein name:
    A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAM-TS 4;ADAM-TS4;ADAMTS-4);
    Alternative:
    Aggrecanase-1;ADMP-1;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Interacts with SRPX2.
    Function:
    Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    839
    Sequence:
    50:
    MSHMDSHPGR | GLADGWLWGI | QPRLLLPTVP | VSGSRLVWLL | LLASLLPSAW | 
    100:
    PASPLPREEE | IVFPEKLNGS | VLPGLGAPAR | LLYRLPAFGE | TLLLELEKDP | 
    150:
    GVQVEGLTVQ | YLGRAPELLG | GAEPGTYLTG | TINGDPESVA | SLHWDGGALL | 
    200:
    GVLQYRGTEL | HIQPLEGGAP | NSAGGPGAHI | LRRKSPVSGQ | GPMCNVKAPP | 
    250:
    GKPSPSPRRA | KRFASLSRFV | ETLVVADDKM | AAFHGAGLKR | YLLTVMAAAA | 
    300:
    KAFKHPSIRN | PVSLVVTRLV | VLGPGEEGPQ | VGPSAAQTLR | SFCAWQRGLN | 
    350:
    TPDDADPGHF | DTAILFTRQD | LCGVSTCDTL | GMADVGTVCD | PARSCAIVED | 
    400:
    DGLQSAFTAA | HELGHVFSML | HDNSKQCTGL | NGPESTSRHV | MAPVMAHVDP | 
    450:
    EEPWSPCSAR | FITDFLDNGF | GHCLLDKPEA | PLHLPVTFPG | KDYDADRQCQ | 
    500:
    LTFGPDSRHC | PQLPPPCAAL | WCSGHLNGHA | MCQTKHSPWA | DGTPCGPAQA | 
    550:
    CMGGRCLHVD | QLQAFNVPQA | GGWGPWGSWG | DCSRSCGGGV | QFSSRDCTRP | 
    600:
    VPRNGGKYCE | GRRTRFRSCN | TQDCPTGSAL | TFREEQCAAY | NHRTDLFKNF | 
    650:
    PGPMDWVPRY | TGVAPRDQCK | LTCQTRALGY | YYVLDPRVAD | GTPCSPDSSS | 
    700:
    VCVQGRCIHA | GCDRVIGSKK | KFDKCMVCGG | DGSSCSKQSG | SFKKFRYGYN | 
    750:
    NVVTIPAGAT | HILVRQQGSP | SVRSLYLALK | LPDGSYALNG | EYTLIPSPTD | 
    800:
    VVLPGAVSLR | YSGATAASET | LSGHGPLAEP | LTLQVLVAGN | PQNARLRYSF | 
    839:
    FVPRPRPVPS | TPRPTPQDWL | RRKSQILEIL | RRRSWAGRK
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine ADAM-TS 4
    Cat.:
    E1804h
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    Packing:
    96T
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    ELISA Kit for Bovine ADAM-TS 4
    Cat.:
    E1804r
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Bovine ADAM-TS 4
    Cat.:
    E1804b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine ADAM-TS 4
    Cat.:
    E1804m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine ADAM-TS 4
    Cat.:
    U1804r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine ADAM-TS 4
    Cat.:
    U1804b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine ADAM-TS 4
    Cat.:
    U1804h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine ADAM-TS 4
    Cat.:
    U1804m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine ADAM-TS 4
    Polyclonal Antibody for Bovine ADAM-TS 4
    Cat.:
    P1804Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine ADAM-TS 4
    Cat.:
    P1804Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine ADAM-TS 4
    Cat.:
    P1804Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine ADAM-TS 4
    Monoclonal Antibody for Bovine ADAM-TS 4
    Monoclonal Antibody for Bovine ADAM-TS 4
    Monoclonal Antibody for Bovine ADAM-TS 4
    Protein for Bovine ADAM-TS 4
    Protein for Bovine ADAM-TS 4
    Protein for Bovine ADAM-TS 4
    Protein for Bovine ADAM-TS 4

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    References
    1. 1.
      "Cloning and characterization of bovine aggrecanase-1."
      Arai M. , Anderson D. , Annis B. , Collins-Racie L. , Corcoran C. , DiBlasio-Smith E. , Morris E. , Dorner A. , LaVallie E.
      Submitted (2002-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Thalamus.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 332-531
      tissue: Cartilage.
    4. 4.
      "n-3 fatty acids specifically modulate catabolic factors involved in articular cartilage degradation."
      Curtis C.L. , Hughes C.E. , Flannery C.R. , Little C.B. , Harwood J.L. , Caterson B.
      J. Biol. Chem.275:721-724(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 332-531
      tissue: Cartilage chondrocyte.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 213-239; 610-615 AND 626-637
      tissue: Cartilage.
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