Protein name:
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS 4;ADAM-TS4;ADAMTS-4) ;
Alternative:
Aggrecanase-1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with SRPX2.
Function:
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
RRTKRFASLS | RFVETLVVAD | DKMAAFHGAG | LKHYLLTVMA | AAAKAFKHPS |
100:
IRNPVNLVVT | RLVILGSGQE | VPQVGPSAAQ | TLRSFCTWQK | GLNPPNDSDP |
150:
DHFDTAILFT | RQDLCGVSTC | DALGMAGVGT | VCDPARSCAI | VEDDGLQSAF |
200:
TAAHELGHVF | NMLHDNSKPC | ANLNGQGSSS | RHVMAPVMAH | VDPEEPWSPC |
250:
SARFITDFLD | NGYGHCLLDK | PEAPLHLPVT | FPGKDYDADR | QCQLTFGPDS |
300:
SHCPQLPPPC | AALWCFGHLN | GHAMCQTKHS | PWADGTPCGP | AQACMGGRCL |
350:
HVDQLKDFNI | PQAGGWGPWG | PWGDCSRTCG | GGVQFSSRDC | TKPVPRNGGK |
400:
YCEGRRTPFR | SCNTKNCPHG | SALTFREEQC | AAYNHRTDLF | KSFPGPMDWV |
450:
PRYTGVAPRD | QCKLTCQARA | LGYYYVLEPR | VADGTPCSPD | SSSVCVQGRC |
500:
IHAGCDRIIG | SKKKFDKCMV | CGGNGSSCSK | QSGSFKKFRY | GYSDVVTIPA |
550:
GRTHILVRQQ | GGSGLKSIYL | ALKLADGSYA | LNGEYTLMPS | STDVVLPGAV |
600:
SLRYSGRTAA | SETLSGHGPL | AQPLTLQVLV | AGNPQNVRLR | YSFFVPRPVP |
630:
STPRPPPQNW | LQRRAEILEI | LRKRTWAGRK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Mouse
ELISA Kit for Rat ADAM-TS 4
ELISA Kit for Rat ADAM-TS 4
ELISA Kit for Rat ADAM-TS 4
ELISA Kit for Rat ADAM-TS 4
CLIA Kit for Rat ADAM-TS 4
CLIA Kit for Rat ADAM-TS 4
CLIA Kit for Rat ADAM-TS 4
CLIA Kit for Rat ADAM-TS 4
Polyclonal Antibody for Rat ADAM-TS 4
Polyclonal Antibody for Rat ADAM-TS 4
Polyclonal Antibody for Rat ADAM-TS 4
Polyclonal Antibody for Rat ADAM-TS 4
Monoclonal Antibody for Rat ADAM-TS 4
Monoclonal Antibody for Rat ADAM-TS 4
Monoclonal Antibody for Rat ADAM-TS 4
Monoclonal Antibody for Rat ADAM-TS 4
Protein for Rat ADAM-TS 4
Protein for Rat ADAM-TS 4
Protein for Rat ADAM-TS 4
Protein for Rat ADAM-TS 4
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Wistar .
tissue :
Brain .