Gm6484 ELISA Kit for Mouse(Mus musculus) | EIAab.comGm6484 ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Gm6484(Gene name) > Mouse

Gm6484 (Gene name),

Betatrophin (Protein name ), BETAT_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

Feedback

Gene name:

Gm6484(Angptl8;Rifl);

Protein name:

Betatrophin;

Alternative:

Lipasin;Angiopoietin-like protein 8;Refeeding-induced fat and liver protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with ANGPTL3.

Function:

Hormone that specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic beta cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

198

Sequence:

50:

100:

150:

198:

TLKARADKQS | HLLWALTGHV | QRQQREMAEQ | QQWLRQIQQR | LHTAALPA

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Mm.440264

KEGG:

mmu:624219

Uniprot:

Q8R1L8

FOR

ELISA Kit for Mouse Betatrophin

Cat.:

E11644m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse Betatrophin

Cat.:

U11644m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

Polyclonal Antibody for Mouse Betatrophin

Cat.:

P11644Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Betatrophin

Protein for Mouse Betatrophin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"Insulin upregulates betatrophin expression via PI4K/Akt pathway"

Puhan L, Xi C, Zeqing Z, et al.

From:Scientific Reports

References

1.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 18-181
strain: FVB/N.
tissue: Liver.
3.

"A mouse knockout library for secreted and transmembrane proteins."
Tang T. , Li L. , Tang J. , Li Y. , Lin W.Y. , Martin F. , Grant D. , Solloway M. , Parker L. , Ye W. , Forrest W. , Ghilardi N. , Oravecz T. , Platt K.A. , Rice D.S. , Hansen G.M. , Abuin A. , Eberhart D.E. , more...
Nat. Biotechnol.28:749-755(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
4.

"Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism."
Ren G. , Kim J.Y. , Smas C.M.
Am. J. Physiol.303:E334-E351(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
5.

"Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels."
Zhang R.
Biochem. Biophys. Res. Commun.424:786-792(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;INDUCTION
6.

"Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family."
Fu Z. , Yao F. , Abou-Samra A.B. , Zhang R.
Biochem. Biophys. Res. Commun.430:1126-1131(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
7.

"Atypical angiopoietin-like protein that regulates ANGPTL3."
Quagliarini F. , Wang Y. , Kozlitina J. , Grishin N.V. , Hyde R. , Boerwinkle E. , Valenzuela D.M. , Murphy A.J. , Cohen J.C. , Hobbs H.H.
Proc. Natl. Acad. Sci. U.S.A.109:19751-19756(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
8.

"Betatrophin: a hormone that controls pancreatic beta cell proliferation."
Yi P. , Park J.S. , Melton D.A.
Cell153:747-758(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
9.

"Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis."
Wang Y. , Quagliarini F. , Gusarova V. , Gromada J. , Valenzuela D.M. , Cohen J.C. , Hobbs H.H.
Proc. Natl. Acad. Sci. U.S.A.110:16109-16114(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
10.

"Elevated mouse hepatic betatrophin expression does not increase human beta-cell replication in the transplant setting."
Jiao Y. , Le Lay J. , Yu M. , Naji A. , Kaestner K.H.
Diabetes63:1283-1288(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: EXPRESSION IN HUMAN PANCREATIC BETA-CELLS
11.

"Perspectives on the activities of ANGPTL8/betatrophin."
Yi P. , Park J.S. , Melton D.A.
Cell159:467-468(2014)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN PANCREATIC BETA-CELLS PROLIFERATION
12.

"ANGPTL8/betatrophin does not control pancreatic beta cell expansion."
Gusarova V. , Alexa C.A. , Na A. , Stevis P.E. , Xin Y. , Bonner-Weir S. , Cohen J.C. , Hobbs H.H. , Murphy A.J. , Yancopoulos G.D. , Gromada J.
Cell159:691-696(2014)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE

Product Feedback Wall

* Email:
*Comments: