CDH1 ELISA Kit for Dog(Canis familiaris) | EIAab.comCDH1 ELISA Kit for Dog(Canis familiaris)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > CDH1(Gene name) > Dog

CDH1 (Gene name),

Cadherin-1 (Protein name ), CADH1_CANFA from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

CDH1;

Protein name:

Cadherin-1;

Alternative:

Uvomorulin;Epithelial cadherin(E-cadherin);

CD:

CD324;

Organism:

Dog (Canis familiarisCanis lupus familiaris).

General Annotation

Sub Unit:

Homodimer; disulfide-linked. Component of an E-cadherin/ catenin adhesion complex composed of at least E-cadherin/CDH1, beta-catenin/CTNNB1 or gamma-catenin/JUP, and potentially alpha-catenin/CTNNA1; the complex is located to adherens junctions. The stable association of CTNNA1 is controversial as CTNNA1 was shown not to bind to F-actin when assembled in the complex. Alternatively, the CTNNA1-containing complex may be linked to F-actin by other proteins such as LIMA1. Interaction with PSEN1, cleaves CDH1 resulting in the disassociation of cadherin-based adherens junctions (CAJs). Interacts with AJAP1, CTNND1 and DLGAP5. Interacts with TBC1D2. Interacts with LIMA1. Interacts with CAV1. Interacts with the TRPV4 and CTNNB1 complex. Interacts with PIP5K1C. Interacts with RAB8B. Interacts with DDR1; this stabilizes CDH1 at the cell surface and inhibits its internalization (By similarity). Interacts with RAPGEF2.

Function:

E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.

Subcellular Location:

Cell junction Cell membrane Single-pass type I membrane protein Endosome Golgi apparatus Trans-Golgi network Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane.

Protein Attributes:

Sequence length:

885

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

885:

LNSSESDQDQ | DYDYLNEWGN | RFKKLADMYG | GGEDD

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

cfa:442858

Pfam:

PF00028

UniGene:

Cfa.3488

Uniprot:

F1PAA9

FOR

ELISA Kit for Dog Cadherin-1

Cat.:

E0017h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Dog Cadherin-1

Cat.:

E0017m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Dog Cadherin-1

Cat.:

E0017r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Dog Cadherin-1

Cat.:

E0017d

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Dog Cadherin-1

Cat.:

E0017b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Dog Cadherin-1

Cat.:

E0017c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Dog Cadherin-1

Cat.:

U0017b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Dog Cadherin-1

Cat.:

U0017c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Dog Cadherin-1

Cat.:

U0017d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Dog Cadherin-1

Cat.:

U0017h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Dog Cadherin-1

Cat.:

U0017m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Dog Cadherin-1

Cat.:

U0017r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

Polyclonal Antibody for Dog Cadherin-1

Cat.:

P0017Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Dog Cadherin-1

Cat.:

P0017Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Dog Cadherin-1

Cat.:

P0017Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Dog Cadherin-1

Monoclonal Antibody for Dog Cadherin-1

Protein for Dog Cadherin-1

Cat.:

R0017m

Price:

Please sign in first.

Packing:

1mg

Purity:

>90%

Protein for Dog Cadherin-1

R&D Technical Data

12% SDS-PAGE Analysis

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤ 6.8%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤ 11.2%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of ACE into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	102	96-105
Plasma	104	94-106

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	93-105%	94-103%	95-105%	92-108%
EDTA plasma(n=5)	89-98%	93-101%	90-99%	90-104%
heparin plasma(n=5)	93-101%	92-102%	99-109%	94-107%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

Product Feedback Wall

* Email:
*Comments: