CDKN2A ELISA Kit for Human(Homo sapiens) | EIAab.comCDKN2A ELISA Kit for Human(Homo sapiens)

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CDKN2A (Gene name),

Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Protein name ), CD2A1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CDKN2A(CDKN2;MTS1);

Protein name:

Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3;

Alternative:

Multiple tumor suppressor 1(MTS-1);Cyclin-dependent kinase 4 inhibitor A(CDK4I);p16-INK4a(p16-INK4;p16INK4A);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer with CDK4 or CDK6. Predominant p16 complexes contained CDK6. Interacts (isoforms 1,2 and 4) with CDK4 (both 'T-172'-phosphorylated and non-phosphorylated forms); the interaction inhibits cyclin D-CDK4 kinase activity. Interacts with ISCO2.

Function:

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

156

Sequence:

50:

100:

150:

156:

PSDIPD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:1029

UniGene:

Hs.512599

SMR:

P42771

Pfam:

PF00023

String:

P42771

MIM:

151623

Pfam:

PF12796

STRING:

9606.ENSP00000355153

Uniprot:

P42771

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ELISA Kit for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

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E0794h

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96T

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ELISA Kit for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

Cat.:

E0794r

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96T

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ELISA Kit for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

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E0794m

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96T

CLIA Kit for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

Cat.:

U0794r

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Packing:

96T

CLIA Kit for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

Cat.:

U0794h

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

Cat.:

U0794m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

Cat.:

P0794Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

Cat.:

P0794Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

Cat.:

P0794Rb-h

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Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

Protein for Human Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3

R&D Technical Data

12% SDS-PAGE Analysis

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4."
Serrano M. , Hannon G.J. , Beach D.
Nature366:704-707(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus."
Robertson K.D. , Jones P.A.
Oncogene18:3810-3820(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);TISSUE SPECIFICITY
3.

"Prevalent involvement of illegitimate V(D)J recombination in chromosome 9p21 deletions in lymphoid leukemia."
Kitagawa Y. , Inoue K. , Sasaki S. , Hayashi Y. , Matsuo Y. , Lieber M.R. , Mizoguchi H. , Yokota J. , Kohno T.
J. Biol. Chem.277:46289-46297(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Human p16gamma, a novel transcriptional variant of p16(INK4A), coexpresses with p16(INK4A) in cancer cells and inhibits cell-cycle progression."
Lin Y.C. , Diccianni M.B. , Kim Y. , Lin H.H. , Lee C.H. , Lin R.J. , Joo S.H. , Li J. , Chuang T.J. , Yang A.S. , Kuo H.H. , Tsai M.D. , Yu A.L.
Oncogene26:7017-7027(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5);ALTERNATIVE SPLICING
5.

NIEHS SNPs program
Submitted (2002-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"DNA sequence and analysis of human chromosome 9."
Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence."
Hara E. , Smith R. , Parry D. , Tahara H. , Stone S. , Peters G.
Mol. Cell. Biol.16:859-867(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-20
9.

"Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers."
Nobori T. , Miura K. , Wu D.J. , Lois A. , Takabayashi K. , Carson D.A.
Nature368:753-756(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 51-156
10.

"A cell cycle regulator potentially involved in genesis of many tumor types."
Kamb A. , Gruis N.A. , Weaver-Feldhaus J. , Liu Q. , Harshman K. , Tavtigian S.V. , Stockert E. , Day R.S. III , Johnson B.E. , Skolnick M.H.
Science264:436-440(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 51-152
11.

"Mutations and altered expression of p16INK4 in human cancer."
Okamoto A. , Demetrick D.J. , Spillare E.A. , Hagiwara K. , Hussain S.P. , Bennett W.P. , Forrester K. , Gerwin B. , Serrano M. , Beach D.H. , Harris C.C.
Proc. Natl. Acad. Sci. U.S.A.91:11045-11049(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
12.

"Phosphorylation of p16INK4A correlates with Cdk4 association."
Gump J. , Stokoe D. , McCormick F.
J. Biol. Chem.278:6619-6622(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-7; SER-8; SER-140 AND SER-152
13.

"Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK 'inhibitors'."
Bockstaele L. , Kooken H. , Libert F. , Paternot S. , Dumont J.E. , de Launoit Y. , Roger P.P. , Coulonval K.
Mol. Cell. Biol.26:5070-5085(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDK4;FUNCTION
14.

"Identification and characterization of a novel protein ISOC2 that interacts with p16INK4a."
Huang X. , Shi Z. , Wang W. , Bai J. , Chen Z. , Xu J. , Zhang D. , Fu S.
Biochem. Biophys. Res. Commun.361:287-293(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ISOC2;SUBCELLULAR LOCATION
15.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
16.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
17.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
18.

"Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a."
Russo A.A. , Tong L. , Lee J.O. , Jeffrey P.D. , Pavletich N.P.
Nature395:237-243(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF COMPLEX WITH CDK6
19.

"Tumor suppressor INK4: comparisons of conformational properties between p16(INK4A) and p18(INK4C)."
Yuan C. , Li J. , Selby T.L. , Byeon I.-J. , Tsai M.-D.
J. Mol. Biol.294:201-211(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
20.

"Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR data."
Yuan C. , Selby T.L. , Li J. , Byeon I.J. , Tsai M.D.
Protein Sci.9:1120-1128(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
21.

"CDKN2 mutations in melanoma."
Dracopoli N.C. , Fountain J.W.
Cancer Surv.26:115-132(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON MELANOMA VARIANTS
22.

"CDKN2A (p16INK4A) somatic and germline mutations."
Smith-Soerensen B. , Hovig E.
Hum. Mutat.7:294-303(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON VARIANTS
23.

"Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas."
Hayashi N. , Sugimoto Y. , Tsuchiya E. , Ogawa M. , Nakamura Y.
Biochem. Biophys. Res. Commun.202:1426-1430(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NON-SMALL CELL LUNG CARCINOMA TYR-66; HIS-84; ALA-93; ALA-95; GLN-99; LEU-114; ALA-120; LYS-120; PRO-132; VAL-134; TYR-142 AND VAL-150
24.

"Germline p16 mutations in familial melanoma."
Hussussian C.J. , Struewing J.P. , Goldstein A.M. , Higgins P.A.T. , Ally D.S. , Sheahan M.D. , Clark W.H. Jr. , Tucker M.A. , Dracopoli N.C.
Nat. Genet.8:15-21(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMM2 PRO-87; TRP-101 AND ASP-126;VARIANTS THR-49; SER-71 AND THR-148
25.

"Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population."
Fitzgerald M.G. , Harkin D.P. , Silva-Arrieta S. , Macdonald D.J. , Lucchina L.C. , Unsal H. , O'Neill E. , Koh J. , Finkelstein D.M. , Isselbacher K.J. , Sober A.J. , Haber D.A.
Proc. Natl. Acad. Sci. U.S.A.93:8541-8545(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMM2 ILE-53 AND CYS-107;VARIANTS VAL-68; THR-85 AND THR-148
26.

"Germline mutations of the CDKN2 gene in UK melanoma families."
Harland M. , Meloni R. , Gruis N. , Pinney E. , Brookes S. , Spurr N.K. , Frischauf A.-M. , Bataille V. , Peters G. , Cuzick J. , Selby P. , Bishop D.T. , Bishop J.N.
Hum. Mol. Genet.6:2061-2067(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMM2 PRO-24; ILE-53 AND THR-118;VARIANT THR-148
27.

"Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France."
Soufir N. , Avril M.-F. , Chompret A. , Demenais F. , Bombled J. , Spatz A. , Stoppa-Lyonnet D. , Benard J. , Bressac-De Paillerets B.
Hum. Mol. Genet.7:209-216(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMM2
28.

Soufir N. , Avril M.-F. , Chompret A. , Demenais F. , Bombled J. , Spatz A. , Stoppa-Lyonnet D. , Benard J. , Bressac-De Paillerets B.
Hum. Mol. Genet.7:941-941(1998)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
29.

"Five novel somatic CDKN2/p16 mutations identified in melanoma, glioma and carcinoma of the pancreas."
Gretarsdottir S. , Olafsdottir G.H. , Borg A.
Hum. Mutat.12:212-212(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMM2 LEU-48; ASP-89 AND MET-117;VARIANT PANCREAS CARCINOMA VAL-57;VARIANT THR-148
30.

"Hereditary TP53 codon 292 and somatic P16INK4A codon 94 mutations in a Li-Fraumeni syndrome family."
Gueran S. , Tunca Y. , Imirzalioglu N.
Cancer Genet. Cytogenet.113:145-151(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LFS GLU-102
31.

"A common founder for the V126D CDKN2A mutation in seven North American melanoma-prone families."
Goldstein A.M. , Liu L. , Shennan M.G. , Hogg D. , Tucker M.A. , Struewing J.P.
Br. J. Cancer85:527-530(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMM2 ASP-126
32.

"A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family."
Randerson-Moor J.A. , Harland M. , Williams S. , Cuthbert-Heavens D. , Sheridan E. , Aveyard J. , Sibley K. , Whitaker L. , Knowles M. , Bishop J.N. , Bishop D.T.
Hum. Mol. Genet.10:55-62(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN MASTS
33.

"The MTS1 gene is frequently mutated in primary human esophageal tumors."
Zhou X. , Tarmin L. , Yin J. , Jiang H.-Y. , Suzuki H. , Rhyu M.-G. , Abraham J.M. , Meltzer S.J.
Oncogene9:3737-3741(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SQUAMOUS CELL CARCINOMA SER-127 AND CYS-144
34.

"Mutations in the p16INK4/MTS1/CDKN2, p15INK4B/MTS2, and p18 genes in primary and metastatic lung cancer."
Okamoto A. , Hussain S.P. , Hagiwara K. , Spillare E.A. , Rusin M.R. , Demetrick D.J. , Serrano M. , Hannon G.J. , Shiseki M. , Zariwala M. , Xiong Y. , Beach D.H. , Yokota J. , Harris C.C.
Cancer Res.55:1448-1451(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS
35.

"Mutations of the CDKN2/p16INK4 gene in Australian melanoma kindreds."
Walker G.J. , Hussussian C.J. , Flores J.F. , Glendening J.M. , Haluska F.G. , Dracopoli N.C. , Hayward N.K. , Fountain J.W.
Hum. Mol. Genet.4:1845-1852(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMM2 PRO-32; ALA-35; GLU-35; ARG-50 AND ILE-53;VARIANT THR-148
36.

"Mutations associated with familial melanoma impair p16INK4 function."
Ranade K. , Hussussian C.J. , Sikorski R.S. , Varmus H.E. , Goldstein A.M. , Tucker M.A. , Serrano M. , Hannon G.J. , Beach D. , Dracopoli N.C.
Nat. Genet.10:114-116(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS THR-49; SER-71; LEU-81; PRO-87; TRP-101; ASP-126 AND THR-148
37.

"Novel germline p16 mutation in familial malignant melanoma in southern Sweden."
Borg A. , Johannsson U. , Johannsson O. , Haakansson S. , Westerdahl J. , Maasbaeck A. , Olsson H. , Ingvar C.
Cancer Res.56:2497-2500(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMM2 ARG-112 INS;VARIANT THR-148
38.

"Germline mutation of ARF in a melanoma kindred."
Hewitt C. , Lee Wu C. , Evans G. , Howell A. , Elles R.G. , Jordan R. , Sloan P. , Read A.P. , Thakker N.
Hum. Mol. Genet.11:1273-1279(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMM2 ARG-122
39.

"CDKN2A mutations in Spanish cutaneous malignant melanoma families and patients with multiple melanomas and other neoplasia."
Ruiz A. , Puig S. , Malvehy J. , Lazaro C. , Lynch M. , Gimenez-Arnau A.M. , Puig L. , Sanchez-Conejo J. , Estivill X. , Castel T.
J. Med. Genet.36:490-493(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMM2 GLY-59; TYR-84; TRP-87 AND TRP-101
40.

"Contribution of germline mutations in BRCA2, P16(INK4A), P14(ARF) and P15 to uveal melanoma."
Hearle N. , Damato B.E. , Humphreys J. , Wixey J. , Green H. , Stone J. , Easton D.F. , Houlston R.S.
Invest. Ophthalmol. Vis. Sci.44:458-462(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE INVOLVEMENT IN SUSCEPTIBILITY TO UVEAL MELANOMA
41.

"A novel L94Q mutation in the CDKN2A gene in a melanoma kindred."
Avbelj M. , Hocevar M. , Trebusak-Podkrajsek K. , Krzisnik C. , Battelino T.
Melanoma Res.13:567-570(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMM2 GLN-94
42.

"Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma-prone families or patients."
Kannengiesser C. , Brookes S. , del Arroyo A.G. , Pham D. , Bombled J. , Barrois M. , Mauffret O. , Avril M.F. , Chompret A. , Lenoir G.M. , Sarasin A. , Peters G. , Bressac-de Paillerets B.
Hum. Mutat.30:564-574(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CMM2 THR-ALA-19 INS; VAL-35; ARG-67; 67-GLY--ASN-71 DEL; TYR-74; PRO-77; PRO-80; THR-81 AND ARG-97;VARIANTS GLN-24; GLY-69 AND SER-114;CHARACTERIZATION OF VARIANTS

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