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Index > Protein center > CD70(Gene name) > Human
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  • CD70 (Gene name),
  • CD70 antigen (Protein name ),  CD70_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CD70(CD27L;CD27LG;TNFSF7);
    Protein name:
    CD70 antigen;
    Alternative:
    Tumor necrosis factor ligand superfamily member 7;CD27 ligand(CD27-L);
    CD:
    CD70;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotrimer.
    Function:
    Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    193
    Sequence:
    50:
    MPEEGSGCSV | RRRPYGCVLR | AALVPLVAGL | VICLVVCIQR | FAQAQQQLPL | 
    100:
    ESLGWDVAEL | QLNHTGPQQD | PRLYWQGGPA | LGRSFLHGPE | LDKGQLRIHR | 
    150:
    DGIYMVHIQV | TLAICSSTTA | SRHHPTTLAV | GICSPASRSI | SLLRLSFHQG | 
    193:
    CTIASQRLTP | LARGDTLCTN | LTGTLLPSRN | TDETFFGVQW | VRP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    KEGG:
    SMR:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human CD70 antigen
    Cat.:
    E15133p
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human CD70 antigen
    Cat.:
    E15133h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human CD70 antigen
    Cat.:
    E15133m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human CD70 antigen
    Cat.:
    U15133m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human CD70 antigen
    Cat.:
    U15133p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human CD70 antigen
    Cat.:
    U15133h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human CD70 antigen
    Polyclonal Antibody for Human CD70 antigen
    Cat.:
    P15133Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human CD70 antigen
    Cat.:
    P15133Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human CD70 antigen
    Monoclonal Antibody for Human CD70 antigen
    Monoclonal Antibody for Human CD70 antigen
    Protein for Human CD70 antigen
    Protein for Human CD70 antigen
    Protein for Human CD70 antigen

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    Linearity
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    References
    1. 1.
      "Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor."
      Goodwin R.G. , Alderson M.R. , Smith C.A. , Armitage R.J. , Vandenbos T. , Jerzy R. , Tough T.W. , Schoenborn M.A. , David-Smith T. , Hennen K. , Falk B. , Cosman D. , Baker E. , Sutherland G.R. , Grabstein K.H. , Farrah T. , Giri J.G. , Beckmann M.P.
      Cell73:447-456(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: B-cell.
    2. 2.
      "The cloning of CD70 and its identification as the ligand for CD27."
      Bowman M.R. , Crimmins M.A. , Yetz-Aldape J. , Kriz R. , Kelleher K. , Herrmann S.
      J. Immunol.152:1756-1761(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    6. 6.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Kidney.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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