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Index > Protein center > Ctgf(Gene name) > Mouse
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  • Ctgf (Gene name),
  • Connective tissue growth factor (Protein name ),  CTGF_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (2)
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  • Gene name:
    Ctgf(Ccn2;Fisp-12;Fisp12;Hcs24);
    Protein name:
    Connective tissue growth factor;
    Alternative:
    Hypertrophic chondrocyte-specific protein 24;CCN family member 2;Protein FISP-12;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin-and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis.
    Subcellular Location:
    Secreted extracellular space extracellular matrix Secreted
    Protein Attributes:
    Sequence length:
    348
    Sequence:
    50:
    MLASVAGPIS | LALVLLALCT | RPATGQDCSA | QCQCAAEAAP | HCPAGVSLVL | 
    100:
    DGCGCCRVCA | KQLGELCTER | DPCDPHKGLF | CDFGSPANRK | IGVCTAKDGA | 
    150:
    PCVFGGSVYR | SGESFQSSCK | YQCTCLDGAV | GCVPLCSMDV | RLPSPDCPFP | 
    200:
    RRVKLPGKCC | EEWVCDEPKD | RTAVGPALAA | YRLEDTFGPD | PTMMRANCLV | 
    250:
    QTTEWSACSK | TCGMGISTRV | TNDNTFCRLE | KQSRLCMVRP | CEADLEENIK | 
    300:
    KGKKCIRTPK | IAKPVKFELS | GCTSVKTYRA | KFCGVCTDGR | CCTPHRTTTL | 
    348:
    PVEFKCPDGE | IMKKNMMFIK | TCACHYNCPG | DNDIFESLYY | RKMYGDMA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Connective tissue growth factor
    Cat.:
    E0010h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Connective tissue growth factor
    Cat.:
    E0010m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Connective tissue growth factor
    Cat.:
    E0010r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Connective tissue growth factor
    Cat.:
    E0010b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Connective tissue growth factor
    Cat.:
    E0010p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Connective tissue growth factor
    Cat.:
    U0010h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Connective tissue growth factor
    Cat.:
    U0010r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Connective tissue growth factor
    Cat.:
    U0010m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Connective tissue growth factor
    Cat.:
    U0010p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Connective tissue growth factor
    Cat.:
    U0010b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Connective tissue growth factor
    Polyclonal Antibody for Mouse Connective tissue growth factor
    Polyclonal Antibody for Mouse Connective tissue growth factor
    Cat.:
    P0010Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Connective tissue growth factor
    Cat.:
    P0010Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Connective tissue growth factor
    Cat.:
    P0010Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Connective tissue growth factor
    Monoclonal Antibody for Mouse Connective tissue growth factor
    Monoclonal Antibody for Mouse Connective tissue growth factor
    Monoclonal Antibody for Mouse Connective tissue growth factor
    Monoclonal Antibody for Mouse Connective tissue growth factor
    Protein for Mouse Connective tissue growth factor
    Protein for Mouse Connective tissue growth factor
    Protein for Mouse Connective tissue growth factor
    Cat.:
    R0010h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse Connective tissue growth factor
    Protein for Mouse Connective tissue growth factor

    R&D Technical Data

    s

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    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.0%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤7.8%

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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery

    Recovery was determined by spiking various levels of CTGF into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    95-103

    Plasma

    98

    96-101

     

     

     

     

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    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of CTGF and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    98-105%

    100-106%

    92-98%

    92-103%

    EDTA plasma(n=5)

    89-98%

    93-100%

    95-102%

    96-103%

    heparin plasma(n=5)

    99-104%

     

    96-105%

    101-108%

    92-99%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein."
      Ryseck R.-P. , Macdonald-Bravo H. , Mattei M.-G. , Bravo R.
      Cell Growth Differ.2:225-233(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    2. 2.
      "Identification of a gene family regulated by transforming growth factor-beta."
      Brunner A. , Chinn J. , Neubauer M.G. , Purchio A.F.
      DNA Cell Biol.10:293-300(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      "Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development."
      Kireeva M.L. , Latinkic B.V. , Kolesnikova T.V. , Chen C.-C. , Yang G.P. , Abler A.S. , Lau L.F.
      Exp. Cell Res.233:63-77(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    7. 7.
      "Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo."
      Babic A.M. , Chen C.-C. , Lau L.F.
      Mol. Cell. Biol.19:2958-2966(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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