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Index > Protein center > PROCR(Gene name) > Human
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  • PROCR (Gene name),
  • Endothelial protein C receptor (Protein name ),  EPCR_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    PROCR(EPCR);
    Protein name:
    Endothelial protein C receptor;
    Alternative:
    Endothelial cell protein C receptor;Activated protein C receptor(APC receptor);
    CD:
    CD201;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    238
    Sequence:
    50:
    MLTTLLPILL | LSGWAFCSQD | ASDGLQRLHM | LQISYFRDPY | HVWYQGNASL | 
    100:
    GGHLTHVLEG | PDTNTTIIQL | QPLQEPESWA | RTQSGLQSYL | LQFHGLVRLV | 
    150:
    HQERTLAFPL | TIRCFLGCEL | PPEGSRAHVF | FEVAVNGSSF | VSFRPERALW | 
    200:
    QADTQVTSGV | VTFTLQQLNA | YNRTRYELRE | FLEDTCVQYV | QKHISAENTK | 
    238:
    GSQTSRSYTS | LVLGVLVGSF | IIAGVAVGIF | LCTGGRRC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    Pfam:
    SMR:
    MIM:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Endothelial protein C receptor
    Cat.:
    E0022h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Endothelial protein C receptor
    Cat.:
    E0022m
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    Packing:
    96T
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    ELISA Kit for Human Endothelial protein C receptor
    Cat.:
    E0022r
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    Packing:
    96T
    ELISA Kit for Human Endothelial protein C receptor
    Cat.:
    E0022b
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    Packing:
    96T
    CLIA Kit for Human Endothelial protein C receptor
    Cat.:
    U0022m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Endothelial protein C receptor
    Cat.:
    U0022b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Endothelial protein C receptor
    Cat.:
    U0022h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Endothelial protein C receptor
    Cat.:
    U0022r
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Endothelial protein C receptor
    Cat.:
    P0022Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Endothelial protein C receptor
    Polyclonal Antibody for Human Endothelial protein C receptor
    Cat.:
    P0022Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Endothelial protein C receptor
    Cat.:
    P0022Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Endothelial protein C receptor
    Monoclonal Antibody for Human Endothelial protein C receptor
    Monoclonal Antibody for Human Endothelial protein C receptor
    Monoclonal Antibody for Human Endothelial protein C receptor
    Protein for Human Endothelial protein C receptor
    Protein for Human Endothelial protein C receptor
    Protein for Human Endothelial protein C receptor
    Protein for Human Endothelial protein C receptor

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    Linearity
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    References
    1. 1.
      "Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor."
      Fukudome K. , Esmon C.T.
      J. Biol. Chem.269:26486-26491(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Endothelial cell.
    2. 2.
      Flens M.J. , Scheffer G.L.
      Submitted (1995-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Structural and functional implications of the intron/exon organization of the human endothelial cell protein C/activated protein C receptor (EPCR) gene: comparison with the structure of CD1/major histocompatibility complex alpha1 and alpha2 domains."
      Simmonds R.E. , Lane D.A.
      Blood94:632-641(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Organization and chromosomal localization of the human endothelial protein C receptor gene."
      Hayashi T. , Nakamura H. , Okada A. , Takebayashi S. , Wakita T. , Yuasa H. , Okumura K. , Suzuki K.
      Gene238:367-373(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      SeattleSNPs variation discovery resource
      Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLY-219
    7. 7.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    8. 8.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLY-219
      tissue: Pancreas.
    11. 11.
      "Metalloproteolytic release of endothelial cell protein C receptor."
      Xu J. , Qu D. , Esmon N.L. , Esmon C.T.
      J. Biol. Chem.275:6038-6044(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF SOLUBLE FORM
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "The crystal structure of the endothelial protein C receptor and a bound phospholipid."
      Oganesyan V. , Oganesyan N. , Terzyan S. , Qu D. , Dauter Z. , Esmon N.L. , Esmon C.T.
      J. Biol. Chem.277:24851-24854(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 18-210;GLYCOSYLATION AT ASN-47; ASN-136 AND ASN-172;DISULFIDE BOND
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