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Index > Protein center > Gdnf(Gene name) > Mouse
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  • Gdnf (Gene name),
  • Glial cell line-derived neurotrophic factor (Protein name ),  GDNF_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Gdnf;
    Protein name:
    Glial cell line-derived neurotrophic factor(mGDNF);
    Alternative:
    Astrocyte-derived trophic factor(ATF);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked.
    Function:
    Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    211
    Sequence:
    50:
    MKLWDVVAVC | LVLLHTASAF | PLPAGKRLLE | APAEDHSLGH | RRVPFALTSD | 
    100:
    SNMPEDYPDQ | FDDVMDFIQA | TIKRLKRSPD | KQAAALPRRE | RNRQAAAASP | 
    150:
    ENSRGKGRRG | QRGKNRGCVL | TAIHLNVTDL | GLGYETKEEL | IFRYCSGSCE | 
    200:
    SAETMYDKIL | KNLSRSRRLT | SDKVGQACCR | PVAFDDDLSF | LDDNLVYHIL | 
    211:
    RKHSAKRCGC | I
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse mGDNF
    Cat.:
    E0043r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse mGDNF
    Cat.:
    E0043h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse mGDNF
    Cat.:
    E0043m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse mGDNF
    Cat.:
    U0043m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse mGDNF
    Cat.:
    U0043h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse mGDNF
    Cat.:
    U0043r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse mGDNF
    Cat.:
    P0043Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse mGDNF
    Cat.:
    P0043Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse mGDNF
    Cat.:
    P0043Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse mGDNF
    Monoclonal Antibody for Mouse mGDNF
    Monoclonal Antibody for Mouse mGDNF
    Protein for Mouse mGDNF
    Protein for Mouse mGDNF
    Protein for Mouse mGDNF

    R&D Technical Data
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    s

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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.3%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤7.5%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    Recovery was determined by spiking various levels of GDNF into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    105

    102-108

    Plasma

    106

    99-107

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of GDNF and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    102-106%

    101-107%

    96-103%

    93-98%

    EDTA plasma(n=5)

    97-105%

    104-108%

    99-103%

    89-96%

    heparin plasma(n=5)

    104-106%

     

    107-110%

    95-99%

    100-105%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Spontaneously immortalized adult mouse Schwann cells secrete autocrine and paracrine growth-promoting activities."
      Watabe K. , Fukuda T. , Tanaka J. , Honda H. , Toyohara K. , Sakai O.
      J. Neurosci. Res.41:279-290(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: ICR.
      tissue: Spinal ganglion.
    2. 2.
      "Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions."
      Hellmich H.L. , Kos L. , Cho E.S. , Mahon K.A. , Zimmer A.
      Mech. Dev.54:95-105(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
      strain: 129/SvJ.
      tissue: Glial cell.
    3. 3.
      "Cloning and structural organization of the gene encoding the mouse glial cell line-derived neurotrophic factor, GDNF."
      Matsushita N. , Fujita Y. , Tanaka M. , Nagatsu T. , Kiuchi K.
      Gene203:149-157(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);NUCLEOTIDE SEQUENCE [GENOMIC DNA];INDUCTION
      tissue: Neonatal brain.
    4. 4.
      "Cloning and characterization of mouse glial cell line-derived neurotrophic growth factor (GDNF)."
      Wang F.-J. , Zhao J. , Too H.P.
      Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao30:375-381(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);PARTIAL NUCLEOTIDE SEQUENCE [GENOMIC DNA];NUCLEOTIDE SEQUENCE [MRNA] OF 1-103 (ISOFORM 2);TISSUE SPECIFICITY
      strain: BALB/c.
      strain: C57BL/10J.
      tissue: Brain.
      tissue: Glial cell.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Brain.
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