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Index > Protein center > SLC8A1(Gene name) > Dog
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  • SLC8A1 (Gene name),
  • Sodium/calcium exchanger 1 (Protein name ),  NAC1_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SLC8A1;
    Protein name:
    Sodium/calcium exchanger 1;
    Alternative:
    Solute carrier family 8 member 1;Na(+)/Ca(2+)-exchange protein 1;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    970
    Sequence:
    50:
    MLQLRLLPTF | SMGCHLLAVV | ALLFSHVDLI | SAETEMEGEG | NETGECTGSY | 
    100:
    YCKKGVILPI | WEPQDPSFGD | KIARATVYFV | AMVYMFLGVS | IIADRFMSSI | 
    150:
    EVITSQEKEI | TIKKPNGETT | KTTVRIWNET | VSNLTLMALG | SSAPEILLSV | 
    200:
    IEVCGHNFTA | GDLGPSTIVG | SAAFNMFIII | ALCVYVVPDG | ETRKIKHLRV | 
    250:
    FFVTAAWSIF | AYTWLYIILS | VISPGVVEVW | EGLLTFFFFP | ICVVFAWVAD | 
    300:
    RRLLFYKYVY | KRYRAGKQRG | MIIEHEGDRP | SSKTEIEMDG | KVVNSHVDNF | 
    350:
    LDGALVLEVD | ERDQDDEEAR | REMARILKEL | KQKHPEKEIE | QLIELANYQV | 
    400:
    LSQQQKSRAF | YRIQATRLMT | GAGNILKRHA | ADQARKAVSM | HEVNTEVAEN | 
    450:
    DPVSKIFFEQ | GTYQCLENCG | TVALTIIRRG | GDLTNTVFVD | FRTEDGTANA | 
    500:
    GSDYEFTEGT | VVFKPGETQK | EIRVGIIDDD | IFEEDENFLV | HLSNVKVSSE | 
    550:
    ASEDGILEAN | HVSALACLGS | PSTATVTIFD | DDHAGIFTFE | EPVTHVSESI | 
    600:
    GIMEVKVLRT | SGARGNVIVP | YKTIEGTARG | GGEDFEDTCG | ELEFQNDEIV | 
    650:
    KTISVKVIDD | EEYEKNKTFF | LEIGEPRLVE | MSEKKALLLN | ELGGFTITGK | 
    700:
    YLYGQPVFRK | VHAREHPIPS | TVITIAEEYD | DKQPLTSKEE | EERRIAEMGR | 
    750:
    PILGEHTKLE | VIIEESYEFK | STVDKLIKKT | NLALVVGTNS | WREQFIEAIT | 
    800:
    VSAGEDDDDD | ECGEEKLPSC | FDYVMHFLTV | FWKVLFAFVP | PTEYWNGWAC | 
    850:
    FIVSILMIGI | LTAFIGDLAS | HFGCTIGLKD | SVTAVVFVAL | GTSVPDTFAS | 
    900:
    KVAATQDQYA | DASIGNVTGS | NAVNVFLGIG | VAWSIAAIYH | AANGEQFKVS | 
    950:
    PGTLAFSVTL | FTIFAFINVG | VLLYRRRPEI | GGELGGPRTA | KLLTSCLFVL | 
    970:
    LWLLYIFFSS | LEAYCHIKGF | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Dog Sodium/calcium exchanger 1
    Cat.:
    E0315h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Dog Sodium/calcium exchanger 1
    Cat.:
    E0315m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Dog Sodium/calcium exchanger 1
    Cat.:
    E0315r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Dog Sodium/calcium exchanger 1
    Cat.:
    E0315b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Dog Sodium/calcium exchanger 1
    Cat.:
    E0315d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Sodium/calcium exchanger 1
    Cat.:
    U0315r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Sodium/calcium exchanger 1
    Cat.:
    U0315h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Dog Sodium/calcium exchanger 1
    Cat.:
    U0315m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Sodium/calcium exchanger 1
    Cat.:
    U0315d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Sodium/calcium exchanger 1
    Cat.:
    U0315b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Dog Sodium/calcium exchanger 1
    Polyclonal Antibody for Dog Sodium/calcium exchanger 1
    Cat.:
    P0315Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Sodium/calcium exchanger 1
    Polyclonal Antibody for Dog Sodium/calcium exchanger 1
    Cat.:
    P0315Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Sodium/calcium exchanger 1
    Cat.:
    P0315Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Dog Sodium/calcium exchanger 1
    Monoclonal Antibody for Dog Sodium/calcium exchanger 1
    Monoclonal Antibody for Dog Sodium/calcium exchanger 1
    Monoclonal Antibody for Dog Sodium/calcium exchanger 1
    Monoclonal Antibody for Dog Sodium/calcium exchanger 1
    Protein for Dog Sodium/calcium exchanger 1
    Protein for Dog Sodium/calcium exchanger 1
    Protein for Dog Sodium/calcium exchanger 1
    Protein for Dog Sodium/calcium exchanger 1
    Protein for Dog Sodium/calcium exchanger 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)-Ca2+ exchanger."
      Nicoll D.A. , Longoni S. , Philipson K.D.
      Science250:562-565(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Heart.
    2. 2.
      "Molecular studies of the cardiac sarcolemmal sodium-calcium exchanger."
      Nicoll D.A. , Philipson K.D.
      Ann. N. Y. Acad. Sci.639:181-188(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Heart.
    3. 3.
      "The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif."
      Nicoll D.A. , Sawaya M.R. , Kwon S. , Cascio D. , Philipson K.D. , Abramson J.
      J. Biol. Chem.281:21577-21581(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 402-541;CALCIUM-BINDING SITES
    4. 4.
      "The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis."
      Besserer G.M. , Ottolia M. , Nicoll D.A. , Chaptal V. , Cascio D. , Philipson K.D. , Abramson J.
      Proc. Natl. Acad. Sci. U.S.A.104:18467-18472(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS) OF 533-721 ALONE AND IN COMPLEX WITH CALCIUM IONS;CALCIUM-BINDING SITES
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