C5 ELISA Kit for Mouse(Mus musculus) | EIAab.comC5 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > C5(Gene name) > Mouse

C5 (Gene name),

Complement C5 (Protein name ), CO5_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

C5(Hc);

Protein name:

Complement C5;

Alternative:

Hemolytic complement;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).

Function:

Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis).

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

1680

Sequence:

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1650:

1680:

WPTDTTCPSC | QAFVENLNNF | AEDLFLNSCE |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00207

SMR:

P06684

KEGG:

mmu:15139

UniGene:

Mm.2168

String:

P06684

Uniprot:

P06684

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ELISA Kit for Mouse Complement C5

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ELISA Kit for Mouse Complement C5

Cat.:

E1969m

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Manual:

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Packing:

96T

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ELISA Kit for Mouse Complement C5

Cat.:

E1969r

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96T

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ELISA Kit for Mouse Complement C5

Cat.:

E1969h

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ELISA Kit for Mouse Complement C5

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CLIA Kit for Mouse Complement C5

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CLIA Kit for Mouse Complement C5

MSDS:

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CLIA Kit for Mouse Complement C5

Cat.:

U1969m

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Mouse Complement C5

MSDS:

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CLIA Kit for Mouse Complement C5

Cat.:

U1969h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Complement C5

Cat.:

P1969Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Complement C5

Cat.:

P1969Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Complement C5

Monoclonal Antibody for Mouse Complement C5

Protein for Mouse Complement C5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"Using gold nanorods core/silver shell nanostructures as model material to probe biodistribution and toxic effects of silver nanoparticles in mice"

J Meng, Y Ji, J Liu, et al.

From:Nanotoxicology

References

1.

"Deficiency of the murine fifth complement component (C5). A 2-base pair gene deletion in a 5'-exon."
Wetsel R.A. , Fleischer D.T. , Haviland D.L.
J. Biol. Chem.265:2435-2440(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"Primary structure of the fifth component of murine complement."
Wetsel R.A. , Ogata R.T. , Tack B.F.
Biochemistry26:737-743(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 41-1680
4.

"Structure of the murine fifth complement component (C5) gene. A large, highly interrupted gene with a variant donor splice site and organizational homology with the third and fourth complement component genes."
Haviland D.L. , Haviland J.C. , Fleischer D.T. , Wetsel R.A.
J. Biol. Chem.266:11818-11825(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GENE STRUCTURE
5.

"Proteome-wide characterization of N-glycosylation events by diagonal chromatography."
Ghesquiere B. , Van Damme J. , Martens L. , Vandekerckhove J. , Gevaert K.
J. Proteome Res.5:2438-2447(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-427
strain: C57BL/6.
tissue: Plasma.
6.

"Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides."
Bernhard O.K. , Kapp E.A. , Simpson R.J.
J. Proteome Res.6:987-995(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-427
strain: C57BL/6.
tissue: Plasma.

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