Gene name:
DEFB103A (BD3;DEFB103;DEFB3) ;
Protein name:
Beta-defensin 103 ;
Alternative:
Defensin, beta 103 ;Beta-defensin 3 (BD-3;DEFB-3;HBD3;hBD-3) ;Defensin-like protein ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
Subcellular Location:
Secreted
Protein Attributes:
50:
MRIHYLLFAL | LFLFLVPVPG | HGGIINTLQK | YYCRVRGGRC | AVLSCLPKEE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
ELISA Kit for Human Beta-defensin 103
CLIA Kit for Human Beta-defensin 103
Polyclonal Antibody for Human Beta-defensin 103
Monoclonal Antibody for Human Beta-defensin 103
Protein for Human Beta-defensin 103
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Citations
[1].
C Zhu, WW Zhang, SY Fang, et al.
[2].
L Ye, YY Qian, Q Li, et al.
[3].
C Zhu, J Wang, T Cheng, et al.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 23-67;FUNCTION;TISSUE SPECIFICITY;INDUCTION;MASS SPECTROMETRY
tissue :
Keratinocyte .
tissue :
Lung epithelium .
tissue :
Tracheal epithelium .
2.
"Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction."
Conejo-Garcia J.-R.
,
Jaumann F.
,
Schulz S.
,
Krause A.
,
Rodriguez-Jimenez F.-J.
,
Forssmann U.
,
Adermann K.
,
Kluever E.
,
Vogelmeier C.
,
Becker D.
,
Hedrich R.
,
Forssmann W.-G.
,
Bals R.
Cell Tissue Res.306:257-264(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION
3.
"Discovery of new human beta-defensins using a genomics-based approach."
Jia H.P.
,
Schutte B.C.
,
Schudy A.
,
Linzmeier R.
,
Guthmiller J.M.
,
Johnson G.K.
,
Tack B.F.
,
Mitros J.P.
,
Rosenthal A.
,
Ganz T.
,
McCray P.B. Jr.
Gene263:211-218(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
4.
Imai Y.
Submitted (2000-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
5.
"EST and genomic database mining yield novel human and mouse beta-defensins."
Adler D.A.
,
Diamond G.
,
Sheppard P.
,
Holloway J.
,
Presnell S.
,
Jaspers S.
,
Whitmore T.
,
Fox B.
,
Gosink J.
,
Rixon M.
,
Gao Z.
,
Haldeman B.
,
O'Hara P.
Submitted (2000-08) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
6.
"Cloning and expression of Chinese human beta defensin-3."
Chen S.
,
He F.
,
Li R.
Submitted (2002-05) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Tonsil .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 23-67