DEFA1 ELISA Kit for Human(Homo sapiens) | EIAab.comDEFA1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > DEFA1(Gene name) > Human

DEFA1 (Gene name),

Neutrophil defensin 1 (Protein name ), DEF1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

DEFA1(DEF1;DEFA2;MRS);

Protein name:

Neutrophil defensin 1;

Alternative:

HNP-1(HP-1;HP1);Defensin, alpha 1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Dimer.

Function:

Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

Sequence:

50:

94:

ESLAPKHPGS | RKNMACYCRI | PACIAGERRY | GTCIYQGRLW | AFCC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:1667

MIM:

125220

SMR:

P59665

Pfam:

PF00323

UniGene:

Hs.380781

String:

P59665

STRING:

9606.ENSP00000372126

Uniprot:

P59665

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ELISA Kit for Human Neutrophil defensin 1

Cat.:

E1649m

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96T

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ELISA Kit for Human Neutrophil defensin 1

Cat.:

E1649h

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96T

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CLIA Kit for Human Neutrophil defensin 1

Cat.:

U1649h

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Packing:

96T

CLIA Kit for Human Neutrophil defensin 1

Cat.:

U1649m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Neutrophil defensin 1

Cat.:

P1649Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Neutrophil defensin 1

Cat.:

P1649Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Neutrophil defensin 1

Protein for Human Neutrophil defensin 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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Citations

[1].

"Proteomic Profile of Unstable Atheroma Plaque: Increased Neutrophil Defensin 1, Clusterin, and Apolipoprotein E Levels in Carotid Secretome"

Aragonès G, Auguet T, Guiu-Jurado E, et al.

From:Journal of proteome research

References

1.

"Isolation and characterization of human defensin cDNA clones."
Daher K.A. , Lehrer R.I. , Ganz T. , Kronenberg M.
Proc. Natl. Acad. Sci. U.S.A.85:7327-7331(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"A myeloid-related sequence that localizes to human chromosome 8q21.1-22."
Mars W.M. , vanTuinen P. , Drabkin H.A. , White J.W. , Saunders G.F.
Blood71:1713-1719(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Differentiation stage-specific expression of a gene during granulopoiesis."
Wiedemann L.M. , Francis G.E. , Lamb R.F. , Burns J.H. , Winnie J.N. , McKenzie E.D. , Birnie G.D.
Leukemia3:227-234(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Inheritance of unequal numbers of the genes encoding the human neutrophil defensins HP-1 and HP-3."
Mars W.M. , Patmasiriwat P. , Maity T. , Huff V. , Weil M.M. , Saunders G.F.
J. Biol. Chem.270:30371-30376(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
5.

"The structure of neutrophil defensin genes."
Linzmeier R. , Michaelson D. , Liu L. , Ganz T.
FEBS Lett.321:267-273(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

Linzmeier R. , Michaelson D. , Liu L. , Ganz T.
FEBS Lett.326:299-300(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
7.

"DNA sequence and analysis of human chromosome 8."
Nusbaum C. , Mikkelsen T.S. , Zody M.C. , Asakawa S. , Taudien S. , Garber M. , Kodira C.D. , Schueler M.G. , Shimizu A. , Whittaker C.A. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Yang X. , Allen N.R. , Anderson S. , Asakawa T. , more...
Nature439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Liver.
9.

"Primary structures of three human neutrophil defensins."
Selsted M.E. , Harwig S.S.L. , Ganz T. , Schilling J.W. , Lehrer R.I.
J. Clin. Invest.76:1436-1439(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 65-94
10.

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z. , Henzel W.J.
Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-34
11.

"Determination of the disulfide array in the human defensin HNP-2. A covalently cyclized peptide."
Selsted M.E. , Harwig S.S.L.
J. Biol. Chem.264:4003-4007(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS
12.

"The isolation and identification of multiple forms of the neutrophil granule peptides from human leukemic cells."
Bateman A. , Singh A. , Shustik C. , Mars W.M. , Solomon S.
J. Biol. Chem.266:7524-7530(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
13.

"Posttranslational processing of defensins in immature human myeloid cells."
Valore E.V. , Ganz T.
Blood79:1538-1544(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
14.

"Antibacterial activity and specificity of the six human alpha-defensins."
Ericksen B. , Wu Z. , Lu W. , Lehrer R.I.
Antimicrob. Agents Chemother.49:269-275(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
15.

"Structural and functional consequences induced by post-translational modifications in alpha-Defensins."
Balducci E. , Bonucci A. , Picchianti M. , Pogni R. , Talluri E.
Int. J. Pept.2011:594723-594723(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ADP-RIBOSYLATION AT ARG-78 AND ARG-88 BY ART1;PHOSPHORYLATION AT TYR-85
16.

"NMR studies of defensin antimicrobial peptides. 1. Resonance assignment and secondary structure determination of rabbit NP-2 and human HNP-1."
Zhang X.-L. , Selsted M.E. , Pardi A.
Biochemistry31:11348-11356(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF DEFENSIN 1
17.

"NMR studies of defensin antimicrobial peptides. 2. Three-dimensional structures of rabbit NP-2 and human HNP-1."
Pardi A. , Zhang X.-L. , Selsted M.E. , Skalicky J.J. , Yip P.F.
Biochemistry31:11357-11364(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF DEFENSIN 1
18.

"Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs."
Zou G. , de Leeuw E. , Li C. , Pazgier M. , Li C. , Zeng P. , Lu W.-Y. , Lubkowski J. , Lu W.
J. Biol. Chem.282:19653-19665(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 65-94;FUNCTION;SUBUNIT

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