Dicer1 ELISA Kit for Mouse(Mus musculus) | EIAab.comDicer1 ELISA Kit for Mouse(Mus musculus)

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Dicer1 (Gene name),

Endoribonuclease Dicer (Protein name ), DICER_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Dicer1(Dicer;Mdcr);

Protein name:

Endoribonuclease Dicer;

Alternative:

Double-strand-specific ribonuclease mDCR-1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with DHX9, EIF2C1, PIWIL1 and PRKRA. Associates with the 60S ribosome.

Function:

Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

1916

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1916:

RALRSLKANQ | PQVPNS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00270

String:

Q8R418

UniGene:

Mm.21135

SMR:

Q8R418

Uniprot:

Q8R418

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ELISA Kit for Mouse Endoribonuclease Dicer

Cat.:

E0156h

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Manual:

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Packing:

96T

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ELISA Kit for Mouse Endoribonuclease Dicer

Cat.:

E0156m

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Packing:

96T

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ELISA Kit for Mouse Endoribonuclease Dicer

Cat.:

E0156c

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Endoribonuclease Dicer

Cat.:

E0156b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Endoribonuclease Dicer

Cat.:

U0156b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Endoribonuclease Dicer

Cat.:

U0156c

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Endoribonuclease Dicer

Cat.:

U0156h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse Endoribonuclease Dicer

Cat.:

U0156m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Endoribonuclease Dicer

Cat.:

P0156Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Endoribonuclease Dicer

Cat.:

P0156Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Endoribonuclease Dicer

Protein for Mouse Endoribonuclease Dicer

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular characterization of a mouse cDNA encoding Dicer, a ribonuclease III ortholog involved in RNA interference."
Nicholson R.H. , Nicholson A.W.
Mamm. Genome13:67-73(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 17-1916
strain: C57BL/6J.
2.

"Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors."
Doi N. , Zenno S. , Ueda R. , Ohki-Hamazaki H. , Ui-Tei K. , Saigo K.
Curr. Biol.13:41-46(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"RNAi and expression of retrotransposons MuERV-L and IAP in preimplantation mouse embryos."
Svoboda P. , Stein P. , Anger M. , Bernstein E. , Hannon G.J. , Schultz R.M.
Dev. Biol.269:276-285(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain: Czech II.
4.

"A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes."
Flemr M. , Malik R. , Franke V. , Nejepinska J. , Sedlacek R. , Vlahovicek K. , Svoboda P.
Cell155:807-816(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF ISOFORM 2;FUNCTION (ISOFORMS 1 AND 2);DISRUPTION PHENOTYPE (ISOFORM 2);TISSUE SPECIFICITY (ISOFORMS 1 AND 2)
5.

"Structural and biochemical insights into the dicing mechanism of mouse Dicer: a conserved lysine is critical for dsRNA cleavage."
Du Z. , Lee J.K. , Tjhen R. , Stroud R.M. , James T.L.
Proc. Natl. Acad. Sci. U.S.A.105:2391-2396(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.68 ANGSTROMS) OF 1647-1910;MUTAGENESIS OF LYS-1800

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