RNASE3 ELISA Kit for Human(Homo sapiens) | EIAab.comRNASE3 ELISA Kit for Human(Homo sapiens)

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RNASE3 (Gene name),

Eosinophil cationic protein (Protein name ), ECP_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (3)

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Gene name:

RNASE3(ECP;RNS3);

Protein name:

Eosinophil cationic protein(ECP);

Alternative:

Ribonuclease 3(RNase 3);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Function:

Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity.

Subcellular Location:

Cytoplasmic granule Matrix of eosinophil's large specific granule.

Protein Attributes:

Sequence length:

160

Sequence:

50:

100:

150:

160:

VVPVHLDTTI |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P12724

MIM:

131398

STRING:

9606.ENSP00000302324

String:

P12724

KEGG:

hsa:6037

Pfam:

PF00074

UniGene:

Hs.73839

Uniprot:

P12724

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ELISA Kit for Human ECP

Cat.:

E1758h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human ECP

Cat.:

E1758r

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Packing:

96T

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ELISA Kit for Human ECP

Cat.:

E1758m

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Packing:

96T

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CLIA Kit for Human ECP

Cat.:

U1758r

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MSDS:

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Packing:

96T

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CLIA Kit for Human ECP

Cat.:

U1758h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human ECP

Cat.:

U1758m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human ECP

Cat.:

P1758Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human ECP

Cat.:

P1758Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human ECP

Cat.:

P1758Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human ECP

Protein for Human ECP

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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Citations

[1].

"interleukin-31 promotes helper t cell type-2 inflmmation in children with allergic rhinitis"

Wenlong L, Renzhong L, Yanqiu C, et al.

From:Pediatric Research

[2].

"Lactate Dehydrogenase Concentration in Nasal Wash Fluid Indicates Severity of Rhinovirus-Induced Wheezy Bronchitis in Preschool Children"

G Cangiano, E Proietti, MN Kronig, et al.

From:The Pediatric Infectious Disease Journal

[3].

"Eosinophilic and Neutrophilic Airway Inflammation in the Phenotyping of Mild-to-Moderate Asthma and Chronic Obstructive Pulmonary Disease"

K Górska, M Paplińska-Goryca, P Nejman-Gryz, et al.

From:Journal of Chronic Obstructive Pulmonary Disease

References

1.

"Human eosinophil cationic protein. Molecular cloning of a cytotoxin and helminthotoxin with ribonuclease activity."
Rosenberg H.F. , Ackerman S.J. , Tenen D.G.
J. Exp. Med.170:163-176(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ARG-124
tissue: Peripheral blood granulocyte.
2.

"Structure and chromosome localization of the human eosinophil-derived neurotoxin and eosinophil cationic protein genes: evidence for intronless coding sequences in the ribonuclease gene superfamily."
Hamann K.J. , Ten R.M. , Loegering D.A. , Jenkins R.B. , Heise M.T. , Schad C.R. , Pease L.R. , Gleich G.J. , Barker R.L.
Genomics7:535-546(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ARG-124
tissue: Fetal liver.
3.

"Eosinophil cationic protein cDNA. Comparison with other toxic cationic proteins and ribonucleases."
Barker R.L. , Loegering D.A. , Ten R.M. , Hamann K.J. , Pease L.R. , Gleich G.J.
J. Immunol.143:952-955(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ARG-124
4.

Simonsen C.C. , Kennedy J. , Comstock L. , Ashton N. , McGrogan M.
Submitted (1990-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ARG-124
tissue: Colon.
5.

"Sequence variation at two eosinophil-associated ribonuclease loci in humans."
Zhang J. , Rosenberg H.F.
Genetics156:1949-1958(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ARG-124
6.

"The DNA sequence and analysis of human chromosome 14."
Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ARG-124
8.

"Identification of polymorphisms in the ECP gene. Relation to disease activity in Hodgkins lymphoma."
Bystrom J. , Molin D. , Jonsson U.B. , Enblad G. , Sundstrom C. , Hogbom E. , Venge P.
Submitted (2001-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 20-160;VARIANTS CYS-72 AND ARG-124
9.

"Biochemical and functional similarities between human eosinophil-derived neurotoxin and eosinophil cationic protein: homology with ribonuclease."
Gleich G.J. , Loegering D.A. , Bell M.P. , Checkel J.L. , Ackerman S.J. , McKean D.J.
Proc. Natl. Acad. Sci. U.S.A.83:3146-3150(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-87
10.

"Antibiotic proteins of human polymorphonuclear leukocytes."
Gabay J.E. , Scott R.W. , Campanelli D. , Griffith J. , Wilde C. , Marra M.N. , Seeger M. , Nathan C.F.
Proc. Natl. Acad. Sci. U.S.A.86:5610-5614(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-47;FUNCTION AS AN ANTIMICROBIAL PROTEIN
11.

"Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase."
Ulrich M. , Petre A. , Youhnovski N. , Proemm F. , Schirle M. , Schumm M. , Pero R.S. , Doyle A. , Checkel J. , Kita H. , Thiyagarajan N. , Acharya K.R. , Schmid-Grendelmeier P. , Simon H.-U. , Schwarz H. , Tsutsui M. , Shimokawa H. , Bellon G. , more...
J. Biol. Chem.283:28629-28640(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NITRATION AT TYR-60
12.

"Bactericidal and membrane disruption activities of the eosinophil cationic protein are largely retained in an N-terminal fragment."
Torrent M. , de la Torre B.G. , Nogues V.M. , Andreu D. , Boix E.
Biochem. J.421:425-434(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH LPS; LTA AND LIPID BILAYERS
13.

"Eosinophil cationic protein aggregation: identification of an N-terminus amyloid prone region."
Torrent M. , Odorizzi F. , Nogues M.V. , Boix E.
Biomacromolecules11:1983-1990(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IN VITRO FORMATION OF AMYLOID-LIKE AGGREGATES;MUTAGENESIS OF ILE-40
14.

"Crystal structure of eosinophil cationic protein at 2.4 A resolution."
Boix E. , Leonidas D.D. , Nikolovski Z. , Nogues M.V. , Cuchillo C.M. , Acharya K.R.
Biochemistry38:16794-16801(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 28-160
15.

"Three-dimensional crystal structure of human eosinophil cationic protein (RNase 3) at 1.75 A resolution."
Mallorqui-Fernandez G. , Pous J. , Peracaula R. , Aymami J. , Maeda T. , Tada H. , Yamada H. , Seno M. , de Llorens R. , Gomis-Rueth F.-X. , Coll M.
J. Mol. Biol.300:1297-1307(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 28-160
16.

"The crystal structure of eosinophil cationic protein in complex with 2',5'-ADP at 2.0 A resolution reveals the details of the ribonucleolytic active site."
Mohan C.G. , Boix E. , Evans H.R. , Nikolovski Z. , Nogues M.V. , Cuchillo C.M. , Acharya K.R.
Biochemistry41:12100-12106(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 28-160

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