EFNA2 ELISA Kit for Human(Homo sapiens) | EIAab.comEFNA2 ELISA Kit for Human(Homo sapiens)

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EFNA2 (Gene name),

Ephrin-A2 (Protein name ), EFNA2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

EFNA2(EPLG6;LERK6);

Protein name:

Ephrin-A2;

Alternative:

HEK7 ligand(HEK7-L);EPH-related receptor tyrosine kinase ligand 6(LERK-6);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5. Interacts with EPHA8; activates EPHA8.

Function:

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.

Subcellular Location:

Cell membrane Lipid-anchor GPI-anchor

Protein Attributes:

Sequence length:

213

Sequence:

50:

100:

150:

200:

213:

LSTIPVLWTL | LGS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:1943

Pfam:

PF00812

SMR:

O43921

MIM:

602756

String:

O43921

UniGene:

Hs.741510

STRING:

9606.ENSP00000215368

Uniprot:

O43921

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ELISA Kit for Human Ephrin-A2

Cat.:

E0301m

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MSDS:

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Packing:

96T

ELISA Kit for Human Ephrin-A2

Cat.:

E0301h

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Manual:

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Packing:

96T

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ELISA Kit for Human Ephrin-A2

Cat.:

E0301c

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MSDS:

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Packing:

96T

CLIA Kit for Human Ephrin-A2

Cat.:

U0301h

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MSDS:

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Packing:

96T

CLIA Kit for Human Ephrin-A2

Cat.:

U0301m

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MSDS:

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Packing:

96T

CLIA Kit for Human Ephrin-A2

Cat.:

U0301c

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Packing:

96T

Polyclonal Antibody for Human Ephrin-A2

Cat.:

P0301Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Ephrin-A2

Cat.:

P0301Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Ephrin-A2

Monoclonal Antibody for Human Ephrin-A2

Protein for Human Ephrin-A2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Characterization of the genes for mouse LERK-3/Ephrin-A3 (Epl3), mouse LERK-4/Ephrin-A4 (Epl4), and human LERK-6/Ephrin-A2 (EPLG6): conservation of intron/exon structure."
Cerretti D.P. , Nelson N.
Genomics47:131-135(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Cloning, chromosomal mapping, and tissue expression of the gene encoding the human Eph-family kinase ligand ephrin-A2."
Aasheim H.-C. , Pedeutour F. , Grosgeorge J. , Logtenberg T.
Biochem. Biophys. Res. Commun.252:378-382(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
3.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"Structural plasticity of EPH receptor A4 facilitates cross-class ephrin signaling."
Bowden T.A. , Aricescu A.R. , Nettleship J.E. , Siebold C. , Rahman-Huq N. , Owens R.J. , Stuart D.I. , Jones E.Y.
Structure17:1386-1397(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 33-177 IN COMPLEX WITH EPHA4;DISULFIDE BONDS;SUBUNIT

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