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Index > Protein center > CCL11(Gene name) > Human
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  • CCL11 (Gene name),
  • Eotaxin (Protein name ),  CCL11_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CCL11(SCYA11);
    Protein name:
    Eotaxin;
    Alternative:
    Eosinophil chemotactic protein;C-C motif chemokine 11;Small-inducible cytokine A11;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    97
    Sequence:
    50:
    MKVSAALLWL | LLIAAAFSPQ | GLAGPASVPT | TCCFNLANRK | IPLQRLESYR | 
    97:
    RITSGKCPQK | AVIFKTKLAK | DICADPKKKW | VQDSMKYLDQ | KSPTPKP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    Pfam:
    KEGG:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Eotaxin
    Cat.:
    E0026h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Eotaxin
    Cat.:
    E0026r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Eotaxin
    Cat.:
    E0026m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Eotaxin
    Cat.:
    E0026b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Eotaxin
    Cat.:
    U0026b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Eotaxin
    Cat.:
    U0026m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Eotaxin
    Cat.:
    U0026h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Eotaxin
    Cat.:
    U0026r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Eotaxin
    Cat.:
    P0026Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Eotaxin
    Cat.:
    P0026Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Eotaxin
    Polyclonal Antibody for Human Eotaxin
    Cat.:
    P0026Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Eotaxin
    Monoclonal Antibody for Human Eotaxin
    Monoclonal Antibody for Human Eotaxin
    Monoclonal Antibody for Human Eotaxin
    Protein for Human Eotaxin
    Protein for Human Eotaxin
    Protein for Human Eotaxin
    Protein for Human Eotaxin

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia."
      Garcia-Zepeda E.A. , Rothenberg M.E. , Ownbey T.R. , Leder P. , Luster A.D.
      Nat. Med.2:449-456(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils."
      Ponath P.D. , Qin S. , Ringler D.J. , Clark-Lewis I. , Wang J. , Kassam N. , Smith H. , Shi X. , Gonzalo J.A. , Newman W. , Gutierrez-Ramos J.-C. , Mackay C.R.
      J. Clin. Invest.97:604-612(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3."
      Kitaura M. , Nakajima T. , Imai T. , Harada S. , Combadiere C. , Tiffany H.L. , Murphy P.M. , Yoshie O.
      J. Biol. Chem.271:7725-7730(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Small intestine.
    4. 4.
      "Human dermal fibroblasts express eotaxin: molecular cloning, mRNA expression, and identification of eotaxin sequence variants."
      Bartels J. , Schlueter C. , Richter E. , Noso N. , Kulke R. , Christophers E. , Schroeder J.-M.
      Biochem. Biophys. Res. Commun.225:1045-1051(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 60-65 AND 75-88;VARIANTS
      tissue: Foreskin.
    5. 5.
      "Genomic organization, complete sequence, and chromosomal location of the gene for human eotaxin (SCYA11), an eosinophil-specific CC chemokine."
      Garcia-Zepeda E.A. , Rothenberg M.E. , Weremowicz S. , Sarafi M.N. , Morton C.C. , Luster A.D.
      Genomics41:471-476(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Placenta.
    6. 6.
      "Genomic organization, sequence, and transcriptional regulation of the human eotaxin gene."
      Hein H. , Schlueter C. , Kulke R. , Christophers E. , Schroeder J.-M. , Bartels J.
      Biochem. Biophys. Res. Commun.237:537-542(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Lung.
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    8. 8.
      "Delayed production of biologically active O-glycosylated forms of human eotaxin by tumor-necrosis-factor-alpha-stimulated dermal fibroblasts."
      Noso N. , Bartels J. , Mallet A.I. , Mochizuki M. , Christophers E. , Schroeder J.-M.
      Eur. J. Biochem.253:114-122(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-94
      tissue: Blood.
    9. 9.
      "Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation."
      Crump M.P. , Rajarathnam K. , Kim K.S. , Clark-Lewis I. , Sykes B.D.
      J. Biol. Chem.273:22471-22479(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
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