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Index > Protein center > LIPG(Gene name) > Human
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  • LIPG (Gene name),
  • Endothelial lipase (Protein name ),  LIPE_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LIPG(UNQ387/PRO719);
    Protein name:
    Endothelial lipase;
    Alternative:
    Endothelial cell-derived lipase(EDL;EL);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Head to tail homodimer.
    Function:
    Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    500
    Sequence:
    50:
    MSNSVPLLCF | WSLCYCFAAG | SPVPFGPEGR | LEDKLHKPKA | TQTEVKPSVR | 
    100:
    FNLRTSKDPE | HEGCYLSVGH | SQPLEDCSFN | MTAKTFFIIH | GWTMSGIFEN | 
    150:
    WLHKLVSALH | TREKDANVVV | VDWLPLAHQL | YTDAVNNTRV | VGHSIARMLD | 
    200:
    WLQEKDDFSL | GNVHLIGYSL | GAHVAGYAGN | FVKGTVGRIT | GLDPAGPMFE | 
    250:
    GADIHKRLSP | DDADFVDVLH | TYTRSFGLSI | GIQMPVGHID | IYPNGGDFQP | 
    300:
    GCGLNDVLGS | IAYGTITEVV | KCEHERAVHL | FVDSLVNQDK | PSFAFQCTDS | 
    350:
    NRFKKGICLS | CRKNRCNSIG | YNAKKMRNKR | NSKMYLKTRA | GMPFRVYHYQ | 
    400:
    MKIHVFSYKN | MGEIEPTFYV | TLYGTNADSQ | TLPLEIVERI | EQNATNTFLV | 
    450:
    YTEEDLGDLL | KIQLTWEGAS | QSWYNLWKEF | RSYLSQPRNP | GRELNIRRIR | 
    500:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    SMR:
    Pfam:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Endothelial lipase
    Cat.:
    E0469m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Endothelial lipase
    Cat.:
    E0469h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Endothelial lipase
    Cat.:
    E0469r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Endothelial lipase
    Cat.:
    U0469m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Endothelial lipase
    Cat.:
    U0469r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Endothelial lipase
    Cat.:
    U0469h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Endothelial lipase
    Cat.:
    P0469Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Endothelial lipase
    Cat.:
    P0469Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Endothelial lipase
    Cat.:
    P0469Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Endothelial lipase
    Monoclonal Antibody for Human Endothelial lipase
    Monoclonal Antibody for Human Endothelial lipase
    Protein for Human Endothelial lipase
    Protein for Human Endothelial lipase
    Protein for Human Endothelial lipase

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    Precision
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    Linearity
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    References
    1. 1.
      "Cloning of a unique lipase from endothelial cells extends the lipase gene family."
      Hirata K. , Dichek H.L. , Cioffi J.A. , Choi S.Y. , Leeper N.J. , Quintana L. , Kronmal G.S. , Cooper A.D. , Quertermous T.
      J. Biol. Chem.274:14170-14175(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Endothelial cell.
    2. 2.
      "A novel endothelial-derived lipase that modulates HDL metabolism."
      Jaye M. , Lynch K.J. , Krawiec J. , Marchadier D. , Maugeais C. , Doan K. , South V. , Amin D. , Perrone M. , Rader D.J.
      Nat. Genet.21:424-428(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Placenta.
    3. 3.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    4. 4.
      NHLBI resequencing and genotyping service (RS&G)
      Submitted (2007-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    7. 7.
      "Characterization of the lipolytic activity of endothelial lipase."
      McCoy M.G. , Sun G.-S. , Marchadier D. , Maugeais C. , Glick J.M. , Rader D.J.
      J. Lipid Res.43:921-929(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    8. 8.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-393
      tissue: Plasma.
    9. 9.
      "Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation."
      Griffon N. , Jin W. , Petty T.J. , Millar J. , Badellino K.O. , Saven J.G. , Marchadier D.H. , Kempner E.S. , Billheimer J. , Glick J.M. , Rader D.J.
      J. Biol. Chem.284:23322-23330(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    10. 10.
      "Association of extreme blood lipid profile phenotypic variation with 11 reverse cholesterol transport genes and 10 non-genetic cardiovascular disease risk factors."
      Morabia A. , Cayanis E. , Costanza M.C. , Ross B.M. , Flaherty M.S. , Alvin G.B. , Das K. , Gilliam T.C.
      Hum. Mol. Genet.12:2733-2743(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SER-96; ILE-111 AND HIS-312
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