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Index > Protein center > Osm(Gene name) > Mouse
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  • Osm (Gene name),
  • Oncostatin-M (Protein name ),  ONCM_MOUSE from NCBI database.
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  • General Annotation
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  • Gene name:
    Osm;
    Protein name:
    Oncostatin-M(OSM);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells (By similarity). Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    263
    Sequence:
    50:
    MQTRLLRTLL | SLTLSLLILS | MALANRGCSN | SSSQLLSQLQ | NQANLTGNTE | 
    100:
    SLLEPYIRLQ | NLNTPDLRAA | CTQHSVAFPS | EDTLRQLSKP | HFLSTVYTTL | 
    150:
    DRVLYQLDAL | RQKFLKTPAF | PKLDSARHNI | LGIRNNVFCM | ARLLNHSLEI | 
    200:
    PEPTQTDSGA | SRSTTTPDVF | NTKIGSCGFL | WGYHRFMGSV | GRVFREWDDG | 
    250:
    STRSRRQSPL | RARRKGTRRI | RVRHKGTRRI | RVRRKGTRRI | WVRRKGSRKI | 
    263:
    RPSRSTQSPT | TRA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse OSM
    Cat.:
    E0110m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse OSM
    Cat.:
    E0110h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse OSM
    Cat.:
    E0110r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse OSM
    Cat.:
    E0110b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse OSM
    Cat.:
    U0110b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse OSM
    Cat.:
    U0110r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse OSM
    Cat.:
    U0110h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse OSM
    Cat.:
    U0110m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse OSM
    Cat.:
    P0110Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse OSM
    Cat.:
    P0110Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse OSM
    Cat.:
    P0110Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse OSM
    Monoclonal Antibody for Mouse OSM
    Monoclonal Antibody for Mouse OSM
    Monoclonal Antibody for Mouse OSM
    Monoclonal Antibody for Mouse OSM
    Protein for Mouse OSM
    Protein for Mouse OSM
    Protein for Mouse OSM
    Protein for Mouse OSM

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    Precision
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    Linearity
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    References
    1. 1.
      "Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway."
      Yoshimura A. , Ichihara M. , Kinjyo I. , Moriyama M. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Hara T. , Miyajima A.
      EMBO J.15:1055-1063(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Dendritic cell.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the OSM receptor beta subunit."
      Tanaka M. , Hara T. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Miyajima A.
      Blood93:804-815(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH OSMR AND IL6ST
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