Protein name:
Ecto-NOX disulfide-thiol exchanger 2 ;
Alternative:
Cytosolic ovarian carcinoma antigen 1 ;APK1 antigen ;Tumor-associated hydroquinone oxidase (tNOX) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock.
Subcellular Location:
Cell membrane
Secreted
extracellular space
Extracellular and plasma membrane-associated.
Protein Attributes:
50:
MQRDFRWLWV | YEIGYAADNS | RTLNVDSTAM | TLPMSDPTAW | ATAMNNLGMA |
100:
PLGIAGQPIL | PDFDPALGMM | TGIPPITPMM | PGLGIVPPPI | PPDMPVVKEI |
150:
IHCKSCTLFP | PNPNLPPPAT | RERPPGCKTV | FVGGLPENGT | EQIIVEVFEQ |
200:
CGEIIAIRKS | KKNFCHIRFA | EEYMVDKALY | LSGYRIRLGS | STDKKDTGRL |
250:
HVDFAQARDD | LYEWECKQRM | LAREERHRRR | MEEERLRPPS | PPPVVHYSDH |
300:
ECSIVAEKLK | DDSKFSEAVQ | TLLTWIERGE | VNRRSANNFY | SMIQSANSHV |
350:
RRLVNEKAAH | EKDMEEAKEK | FKQALSGILI | QFEQIVAVYH | SASKQKAWDH |
400:
FTKAQRKNIS | VWCKQAEEIR | NIHNDELMGI | RREEEMEMSD | DEIEEMTETK |
450:
ETEESALVSQ | AEALKEENDS | LRWQLDAYRN | EVELLKQEQG | KVHREDDPNK |
500:
EQQLKLLQQA | LQGMQQHLLK | VQEEYKKKEA | ELEKLKDDKL | QVEKMLENLK |
550:
EKESCASRLC | ASNQDSEYPL | EKTMNSSPIK | SEREALLVGI | ISTFLHVHPF |
600:
GASIEYICSY | LHRLDNKICT | SDVECLMGRL | QHTFKQEMTG | VGASLEKRWK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Ecto-NOX disulfide-thiol exchanger 2
ELISA Kit for Human Ecto-NOX disulfide-thiol exchanger 2
CLIA Kit for Human Ecto-NOX disulfide-thiol exchanger 2
CLIA Kit for Human Ecto-NOX disulfide-thiol exchanger 2
Polyclonal Antibody for Human Ecto-NOX disulfide-thiol exchanger 2
Polyclonal Antibody for Human Ecto-NOX disulfide-thiol exchanger 2
Monoclonal Antibody for Human Ecto-NOX disulfide-thiol exchanger 2
Monoclonal Antibody for Human Ecto-NOX disulfide-thiol exchanger 2
Protein for Human Ecto-NOX disulfide-thiol exchanger 2
Protein for Human Ecto-NOX disulfide-thiol exchanger 2
R&D Technical Data
12% SDS-PAGE Analysis
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);ENZYME REGULATION;MUTAGENESIS OF MET-396; CYS-505; CYS-510; HIS-546; CYS-558; HIS-562; CYS-569; CYS-575; GLY-592 AND CYS-602;COFACTOR
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (ISOFORMS 1 AND 2)
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more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Muscle .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 17-405
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 86-90; 249-266 AND 318-333
tissue :
Cervix carcinoma .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 275-610;SUBCELLULAR LOCATION;GLYCOSYLATION
tissue :
Ovarian carcinoma .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ENZYME REGULATION
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;ENZYME REGULATION
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : HYDROQUINONE OXIDASE ACTIVITY
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PRION-LIKE PROPERTIES
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISEASE
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN BIOLOGICAL CLOCK CONTROL
16.
"Diagnostic exome sequencing in persons with severe intellectual disability."
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Vissers L.E.
N. Engl. J. Med.367:1921-1929(2012)
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Cited for : VARIANT ILE-202