Epor ELISA Kit for Rat(Rattus norvegicus) | EIAab.comEpor ELISA Kit for Rat(Rattus norvegicus)

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Epor (Gene name),

Erythropoietin receptor (Protein name ), EPOR_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Epor;

Protein name:

Erythropoietin receptor(EPO-R);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Forms homodimers on EPO stimulation. The tyrosine-phosphorylated form interacts with several SH2 domain-containing proteins including LYN, the adapter protein APS, PTPN6, PTPN11, JAK2, PI3 kinases, STAT5A/B, SOCS3 and CRKL. The N-terminal SH2 domain of PTPN6 binds Tyr-453 and inhibits signaling through dephosphorylation of JAK2. APS binding also inhibits the JAK-STAT signaling. Binding to PTPN11, preferentially through the N-terminal SH2 domain, promotes mitogenesis and phosphorylation of PTPN11. Binding of JAK2 (through its N-terminal) promotes cell-surface expression. Interaction with the ubiquitin ligase NOSIP mediates EPO-induced cell proliferation. Interacts with ATXN2L and INPP5D/SHIP1.

Function:

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate LYN tyrosine kinase.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

507

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

507:

PSYVACS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000017369

String:

Q07303

SMR:

Q07303

UniGene:

Rn.22394

Pfam:

PF09067

Uniprot:

Q07303

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ELISA Kit for Rat EPO-R

Cat.:

E0027h

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Packing:

96T

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ELISA Kit for Rat EPO-R

Cat.:

E0027r

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96T

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ELISA Kit for Rat EPO-R

Cat.:

E0027p

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96T

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ELISA Kit for Rat EPO-R

Cat.:

E0027m

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96T

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ELISA Kit for Rat EPO-R

Cat.:

E0027d

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Packing:

96T

CLIA Kit for Rat EPO-R

Cat.:

U0027r

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MSDS:

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Packing:

96T

CLIA Kit for Rat EPO-R

Cat.:

U0027m

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MSDS:

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Packing:

96T

CLIA Kit for Rat EPO-R

Cat.:

U0027d

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MSDS:

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Packing:

96T

CLIA Kit for Rat EPO-R

Cat.:

U0027p

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat EPO-R

Cat.:

U0027h

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Looking for manual.

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96T

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Polyclonal Antibody for Rat EPO-R

Cat.:

P0027Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat EPO-R

Cat.:

P0027Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat EPO-R

Cat.:

P0027Rb-m

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat EPO-R

Protein for Rat EPO-R

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells."
Masuda S. , Nagao M. , Takahata K. , Konishi Y. , Gallyas F. , Tabira T. , Sasaki R.
J. Biol. Chem.268:11208-11216(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM EPOR-F)
tissue: Pheochromocytoma.
2.

"Alternative splicing of the erythropoietin receptor gene correlates with erythroid differentiation in rat hematopoietic and leukemic cells."
Fujita M. , Takahashi R. , Kitada K. , Watanabe R. , Kitazawa S. , Ashoori F. , Liang P. , Saya H. , Serikawa T. , Maeda S.
Cancer Lett.112:47-55(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS EPOR-F AND EPOR-S)
strain: Long Evans.

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