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Index > Protein center > FABP4(Gene name) > Human
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  • FABP4 (Gene name),
  • Fatty acid-binding protein, adipocyte (Protein name ),  FABP4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (2)
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  • Gene name:
    FABP4;
    Protein name:
    Fatty acid-binding protein, adipocyte;
    Alternative:
    Adipocyte-type fatty acid-binding protein(A-FABP;AFABP);Adipocyte lipid-binding protein(ALBP);Fatty acid-binding protein 4;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with PPARG (By similarity). Monomer.
    Function:
    Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
    Subcellular Location:
    Cytoplasm Nucleus Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.
    Protein Attributes:
    Sequence length:
    132
    Sequence:
    50:
    MCDAFVGTWK | LVSSENFDDY | MKEVGVGFAT | RKVAGMAKPN | MIISVNGDVI | 
    100:
    TIKSESTFKN | TEISFILGQE | FDEVTADDRK | VKSTITLDGG | VLVHVQKWDG | 
    132:
    KSTTIKRKRE | DDKLVVECVM | KGVTSTRVYE | RA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    MIM:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Fatty acid-binding protein, adipocyte
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    E0184h
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    96T
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    ELISA Kit for Human Fatty acid-binding protein, adipocyte
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    E0184r
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    96T
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    ELISA Kit for Human Fatty acid-binding protein, adipocyte
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    E0184m
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    96T
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    ELISA Kit for Human Fatty acid-binding protein, adipocyte
    Cat.:
    E0184p
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Fatty acid-binding protein, adipocyte
    Cat.:
    E0184b
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    Packing:
    96T
    CLIA Kit for Human Fatty acid-binding protein, adipocyte
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    U0184p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Fatty acid-binding protein, adipocyte
    Cat.:
    U0184m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Fatty acid-binding protein, adipocyte
    Cat.:
    U0184r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Fatty acid-binding protein, adipocyte
    Cat.:
    U0184h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Fatty acid-binding protein, adipocyte
    Cat.:
    U0184b
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Fatty acid-binding protein, adipocyte
    Cat.:
    P0184Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Fatty acid-binding protein, adipocyte
    Polyclonal Antibody for Human Fatty acid-binding protein, adipocyte
    Cat.:
    P0184Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Fatty acid-binding protein, adipocyte
    Polyclonal Antibody for Human Fatty acid-binding protein, adipocyte
    Cat.:
    P0184Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Fatty acid-binding protein, adipocyte
    Monoclonal Antibody for Human Fatty acid-binding protein, adipocyte
    Monoclonal Antibody for Human Fatty acid-binding protein, adipocyte
    Monoclonal Antibody for Human Fatty acid-binding protein, adipocyte
    Monoclonal Antibody for Human Fatty acid-binding protein, adipocyte
    Protein for Human Fatty acid-binding protein, adipocyte
    Protein for Human Fatty acid-binding protein, adipocyte
    Protein for Human Fatty acid-binding protein, adipocyte
    Protein for Human Fatty acid-binding protein, adipocyte
    Protein for Human Fatty acid-binding protein, adipocyte
    Cat.:
    R0184h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

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    References
    1. 1.
      "Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA."
      Baxa C.A. , Sha R.S. , Buelt M.K. , Smith A.J. , Matarese V. , Chinander L.L. , Boundy K.L. , Bernlohr D.A.
      Biochemistry28:8683-8690(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Urinary bladder.
    6. 6.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT CYS-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ASP-23
    8. 8.
      "Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target."
      Lehmann F. , Haile S. , Axen E. , Medina C. , Uppenberg J. , Svensson S. , Lundbaeck T. , Rondahl L. , Barf T.
      Bioorg. Med. Chem. Lett.14:4445-4448(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH SYNTHETIC INHIBITOR
    9. 9.
      "Expression, purification, crystallization and structure of human adipocyte lipid-binding protein (aP2)."
      Marr E. , Tardie M. , Carty M. , Brown Phillips T. , Wang I.-K. , Soeller W. , Qiu X. , Karam G.
      Acta Crystallogr. F62:1058-1060(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) IN COMPLEX WITH FATTY ACID;SUBUNIT;PARTIAL PROTEIN SEQUENCE;IDENTIFICATION BY MASS SPECTROMETRY
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