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Index > Protein center > Fth1(Gene name) > Mouse
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  • Fth1 (Gene name),
  • Ferritin heavy chain (Protein name ),  FRIH_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Fth1(Fth);
    Protein name:
    Ferritin heavy chain(Ferritin H subunit);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
    Function:
    Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    182
    Sequence:
    50:
    MTTASPSQVR | QNYHQDAEAA | INRQINLELY | ASYVYLSMSC | YFDRDDVALK | 
    100:
    NFAKYFLHQS | HEEREHAEKL | MKLQNQRGGR | IFLQDIKKPD | RDDWESGLNA | 
    150:
    MECALHLEKS | VNQSLLELHK | LATDKNDPHL | CDFIETYYLS | EQVKSIKELG | 
    182:
    DHVTNLRKMG | APEAGMAEYL | FDKHTLGHGD | ES
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Ferritin H subunit
    Cat.:
    E0518r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Ferritin H subunit
    Cat.:
    E0518h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Ferritin H subunit
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse Ferritin H subunit
    Cat.:
    E0518m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Ferritin H subunit
    Cat.:
    E0518p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Ferritin H subunit
    Cat.:
    E0518b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Ferritin H subunit
    Cat.:
    E0518d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Ferritin H subunit
    Cat.:
    U0518d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Ferritin H subunit
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Ferritin H subunit
    Cat.:
    U0518h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Ferritin H subunit
    Cat.:
    U0518r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Ferritin H subunit
    Cat.:
    U0518b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Ferritin H subunit
    Cat.:
    U0518m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Ferritin H subunit
    Cat.:
    U0518p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Ferritin H subunit
    Cat.:
    P0518Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Ferritin H subunit
    Polyclonal Antibody for Mouse Ferritin H subunit
    Cat.:
    P0518Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Ferritin H subunit
    Polyclonal Antibody for Mouse Ferritin H subunit
    Cat.:
    P0518Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Ferritin H subunit
    Polyclonal Antibody for Mouse Ferritin H subunit
    Monoclonal Antibody for Mouse Ferritin H subunit
    Cat.:
    M0518h
    Price:
    Please sign in first.
    Packing:
    40ug
    Monoclonal Antibody for Mouse Ferritin H subunit
    Monoclonal Antibody for Mouse Ferritin H subunit
    Monoclonal Antibody for Mouse Ferritin H subunit
    Monoclonal Antibody for Mouse Ferritin H subunit
    Monoclonal Antibody for Mouse Ferritin H subunit
    Monoclonal Antibody for Mouse Ferritin H subunit
    Protein for Mouse Ferritin H subunit
    Protein for Mouse Ferritin H subunit
    Protein for Mouse Ferritin H subunit
    Protein for Mouse Ferritin H subunit
    Cat.:
    R0518h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse Ferritin H subunit
    Protein for Mouse Ferritin H subunit
    Protein for Mouse Ferritin H subunit

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    References
    1. 1.
      "Nucleotide sequence of the mouse ferritin H chain gene."
      Yachaou A. , Renaudie F. , Grandchamp B. , Beaumont C.
      Nucleic Acids Res.17:8005-8005(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: BALB/c.
    2. 2.
      "Nucleotide sequence of cDNA encoding the heavy subunit of mouse macrophage ferritin."
      Miyazaki Y. , Setoguchi M. , Higuchi Y. , Yoshida S. , Akizuki S. , Yamamoto S.
      Nucleic Acids Res.16:10373-10373(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: ICR.
      tissue: Macrophage.
    3. 3.
      "The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene."
      Torti S.V. , Kwak E.L. , Miller S.C. , Miller L.L. , Ringold G.M. , Myambo K.B. , Young A.P. , Torti F.M.
      J. Biol. Chem.263:12638-12644(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Murine ferritin heavy chain: isolation and characterization of a functional gene."
      Kwak E.L. , Torti S.V. , Torti F.M.
      Gene94:255-261(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
    5. 5.
      "Transcriptional regulation of ferritin H and L subunits in adult erythroid and liver cells from the mouse. Unambiguous identification of mouse ferritin subunits and in vitro formation of the ferritin shells."
      Beaumont C. , Dugast I. , Renaudie F. , Souroujon M. , Grandchamp B.
      J. Biol. Chem.264:7498-7504(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    6. 6.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Amnion.
      tissue: Heart.
      tissue: Kidney.
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Mammary tumor.
    8. 8.
      Lubec G. , Klug S.
      Submitted (2007-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 11-23 AND 55-64;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Hippocampus.
    9. 9.
      "Early embryonic lethality of H ferritin gene deletion in mice."
      Ferreira C. , Bucchini D. , Martin M.E. , Levi S. , Arosio P. , Grandchamp B. , Beaumont C.
      J. Biol. Chem.275:3021-3024(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;DEVELOPMENTAL STAGE
    10. 10.
      "H ferritin knockout mice: a model of hyperferritinemia in the absence of iron overload."
      Ferreira C. , Santambrogio P. , Martin M.E. , Andrieu V. , Feldmann G. , Henin D. , Beaumont C.
      Blood98:525-532(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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