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Index > Protein center > Hgf(Gene name) > Mouse
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  • Hgf (Gene name),
  • Hepatocyte growth factor (Protein name ),  HGF_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Hgf;
    Protein name:
    Hepatocyte growth factor;
    Alternative:
    Scatter factor(SF);Hepatopoietin-A;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Dimer of an alpha chain and a beta chain linked by a disulfide bond.
    Function:
    HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    728
    Sequence:
    50:
    MMWGTKLLPV | LLLQHVLLHL | LLLHVAIPYA | EGQKKRRNTL | HEFKKSAKTT | 
    100:
    LTKEDPLLKI | KTKKVNSADE | CANRCIRNRG | FTFTCKAFVF | DKSRKRCYWY | 
    150:
    PFNSMSSGVK | KGFGHEFDLY | ENKDYIRNCI | IGKGGSYKGT | VSITKSGIKC | 
    200:
    QPWNSMIPHE | HSFLPSSYRG | KDLQENYCRN | PRGEEGGPWC | FTSNPEVRYE | 
    250:
    VCDIPQCSEV | ECMTCNGESY | RGPMDHTESG | KTCQRWDQQT | PHRHKFLPER | 
    300:
    YPDKGFDDNY | CRNPDGKPRP | WCYTLDPDTP | WEYCAIKTCA | HSAVNETDVP | 
    350:
    METTECIQGQ | GEGYRGTSNT | IWNGIPCQRW | DSQYPHKHDI | TPENFKCKDL | 
    400:
    RENYCRNPDG | AESPWCFTTD | PNIRVGYCSQ | IPKCDVSSGQ | DCYRGNGKNY | 
    450:
    MGNLSKTRSG | LTCSMWDKNM | EDLHRHIFWE | PDASKLNKNY | CRNPDDDAHG | 
    500:
    PWCYTGNPLI | PWDYCPISRC | EGDTTPTIVN | LDHPVISCAK | TKQLRVVNGI | 
    550:
    PTQTTVGWMV | SLKYRNKHIC | GGSLIKESWV | LTARQCFPAR | NKDLKDYEAW | 
    600:
    LGIHDVHERG | EEKRKQILNI | SQLVYGPEGS | DLVLLKLARP | AILDNFVSTI | 
    650:
    DLPSYGCTIP | EKTTCSIYGW | GYTGLINADG | LLRVAHLYIM | GNEKCSQHHQ | 
    700:
    GKVTLNESEL | CAGAEKIGSG | PCEGDYGGPL | ICEQHKMRMV | LGVIVPGRGC | 
    728:
    AIPNRPGIFV | RVAYYAKWIH | KVILTYKL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Hepatocyte growth factor
    Cat.:
    E0047h
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    96T
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    ELISA Kit for Mouse Hepatocyte growth factor
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    E0047r
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    96T
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    ELISA Kit for Mouse Hepatocyte growth factor
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    E0047m
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    96T
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    ELISA Kit for Mouse Hepatocyte growth factor
    Cat.:
    E0047b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Hepatocyte growth factor
    Cat.:
    E0047d
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    MSDS:
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    96T
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    CLIA Kit for Mouse Hepatocyte growth factor
    Cat.:
    U0047d
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Hepatocyte growth factor
    Cat.:
    U0047r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Hepatocyte growth factor
    Cat.:
    U0047m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Hepatocyte growth factor
    Cat.:
    U0047h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Hepatocyte growth factor
    Cat.:
    U0047b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Hepatocyte growth factor
    Cat.:
    P0047Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Hepatocyte growth factor
    Polyclonal Antibody for Mouse Hepatocyte growth factor
    Cat.:
    P0047Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Hepatocyte growth factor
    Cat.:
    P0047Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Hepatocyte growth factor
    Monoclonal Antibody for Mouse Hepatocyte growth factor
    Monoclonal Antibody for Mouse Hepatocyte growth factor
    Monoclonal Antibody for Mouse Hepatocyte growth factor
    Monoclonal Antibody for Mouse Hepatocyte growth factor
    Monoclonal Antibody for Mouse Hepatocyte growth factor
    Protein for Mouse Hepatocyte growth factor
    Protein for Mouse Hepatocyte growth factor
    Protein for Mouse Hepatocyte growth factor
    Protein for Mouse Hepatocyte growth factor
    Protein for Mouse Hepatocyte growth factor

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Identification of mouse mammary fibroblast-derived mammary growth factor as hepatocyte growth factor."
      Sasaki M. , Nishio M. , Sasaki T. , Enami J.
      Biochem. Biophys. Res. Commun.199:772-779(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS LONG AND SHORT);PROTEIN SEQUENCE OF 496-504
      tissue: Mammary fibroblast.
    2. 2.
      "Structure, genetic mapping, and expression of the mouse Hgf/scatter factor gene."
      Lee C.C. , Kozak C.A. , Yamada K.M.
      Cell Adhes. Commun.1:101-111(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    3. 3.
      "Molecular cloning and characterization of cDNA encoding mouse hepatocyte growth factor."
      Liu Y. , Michalopoulos G.K. , Zarnegar R.
      Biochim. Biophys. Acta1216:299-303(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    4. 4.
      "NK1, a natural splice variant of hepatocyte growth factor/scatter factor, is a partial agonist in vivo."
      Jakubczak J.L. , LaRochelle W.J. , Merlino G.
      Mol. Cell. Biol.18:1275-1283(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM NK1)
      tissue: Lung.
    5. 5.
      Sharpe M.J.S. , Lane K. , Gherardi E.
      Submitted (1999-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG)
      strain: Swiss.
      tissue: Fibroblast.
    6. 6.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG)
      tissue: Brain.
    8. 8.
      "Characterisation of the scatter factor/hepatocyte growth factor gene promoter: positive and negative regulatory elements direct gene expression to mesenchymal cells."
      Plaschke-Schluetter A. , Behrens J. , Gherardi E. , Birchmeier W.
      J. Biol. Chem.270:830-836(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-30
      strain: 129.
    9. 9.
      "Purified scatter factor stimulates epithelial and vascular endothelial cell migration."
      Rosen E.M. , Meromsky L. , Setter E. , Vinter D.W. , Goldberg I.D.
      Proc. Soc. Exp. Biol. Med.195:34-43(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 184-197; 357-367; 375-383 AND 653-666
    10. 10.
      "Hepatocytes and scatter factor."
      Gherardi E. , Stoker M.
      Nature346:228-228(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 496-519
    11. 11.
      "Purification and characterization of biologically active scatter factor from ras-transformed NIH 3T3 conditioned medium."
      Coffer A. , Fellows J. , Young S. , Pappin D. , Rahman D.
      Biochem. J.278:35-41(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 496-519
    12. 12.
      "A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist."
      Tolbert W.D. , Daugherty J. , Gao C. , Xie Q. , Miranti C. , Gherardi E. , Woude G.V. , Xu H.E.
      Proc. Natl. Acad. Sci. U.S.A.104:14592-14597(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 29-210;DISULFIDE BONDS
    13. 13.
      "Structural basis for agonism and antagonism of hepatocyte growth factor."
      Tolbert W.D. , Daugherty-Holtrop J. , Gherardi E. , Vande Woude G. , Xu H.E.
      Proc. Natl. Acad. Sci. U.S.A.107:13264-13269(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 31-127;DISULFIDE BONDS;FUNCTION
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