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Index > Protein center > IL11(Gene name) > Human
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  • IL11 (Gene name),
  • Interleukin-11 (Protein name ),  IL11_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    IL11;
    Protein name:
    Interleukin-11(IL-11);
    Alternative:
    Adipogenesis inhibitory factor(AGIF);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    199
    Sequence:
    50:
    MNCVCRLVLV | VLSLWPDTAV | APGPPPGPPR | VSPDPRAELD | STVLLTRSLL | 
    100:
    ADTRQLAAQL | RDKFPADGDH | NLDSLPTLAM | SAGALGALQL | PGVLTRLRAD | 
    150:
    LLSYLRHVQW | LRRAGGSSLK | TLEPELGTLQ | ARLDRLLRRL | QLLMSRLALP | 
    199:
    QPPPDPPAPP | LAPPSSAWGG | IRAAHAILGG | LHLTLDWAVR | GLLLLKTRL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    MIM:
    SMR:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human IL-11
    Cat.:
    E0057h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IL-11
    Cat.:
    E0057m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IL-11
    Cat.:
    E0057r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IL-11
    Cat.:
    U0057r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IL-11
    Cat.:
    U0057m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IL-11
    Cat.:
    U0057h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human IL-11
    Cat.:
    P0057Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IL-11
    Cat.:
    P0057Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IL-11
    Cat.:
    P0057Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human IL-11
    Monoclonal Antibody for Human IL-11
    Monoclonal Antibody for Human IL-11
    Protein for Human IL-11
    Protein for Human IL-11
    Protein for Human IL-11

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine."
      Paul S.R. , Bennett F. , Calvetti J.A. , Kelleher K. , Wood C.R. , O'Hara R.M. Jr. , Leary A.C. , Sibley B.S. , Clark S.C. , Williams D.A. , Yang Y.-C.
      Proc. Natl. Acad. Sci. U.S.A.87:7512-7516(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION
    2. 2.
      "Molecular cloning of cDNA encoding adipogenesis inhibitory factor and identity with interleukin-11."
      Kawashima I. , Ohsumi J. , Mita-Honjo K. , Shimoda-Takano K. , Ishikawa H. , Sakakibara S. , Miyadai K. , Takiguchi Y.
      FEBS Lett.283:199-202(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION
      tissue: Bone marrow.
    3. 3.
      "Genomic sequence and chromosomal location of human interleukin-11 gene (IL11)."
      McKinley D. , Wu Q. , Yang-Feng T. , Yang Y.C.
      Genomics13:814-819(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
    4. 4.
      SeattleSNPs variation discovery resource
      Submitted (2002-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);VARIANTS MET-108 AND HIS-112
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    6. 6.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Prostate.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;MUTAGENESIS OF HIS-182 AND ASP-186
    9. 9.
      "The structure of human interleukin-11 reveals receptor-binding site features and structural differences from interleukin-6."
      Putoczki T.L. , Dobson R.C. , Griffin M.D.W.
      Acta Crystallogr. D70:2277-2285(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.09 ANGSTROMS) OF 23-199
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