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Index > Protein center > IL12B(Gene name) > Pig
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  • IL12B (Gene name),
  • Interleukin-12 subunit beta (Protein name ),  IL12B_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    IL12B;
    Protein name:
    Interleukin-12 subunit beta(IL-12B);
    Alternative:
    IL-12 subunit p40;Cytotoxic lymphocyte maturation factor 40 kDa subunit(CLMF p40);
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12. Heterodimer with IL23A; disulfide-linked. The heterodimer is known as interleukin IL-23. Also secreted as a monomer.
    Function:
    Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    324
    Sequence:
    50:
    MHLQQLVVSW | FSLVWLASPI | VAIWELEKNV | YVVELDWYPN | APGEMVVLTC | 
    100:
    NTPEEDGITW | TSDQSSEVLG | TGKTLTIHVK | EFGDAGQYTC | RKGGAVLSQS | 
    150:
    LLLLHKKEDG | IWSTDILKDQ | KEPKNKSFLK | CEAKNYSGRF | TCWWLTAIST | 
    200:
    DLKFSVKSSR | GSTDPRGVTC | GTATLSEDLG | EYKKYRVECQ | EGSACPAAEE | 
    250:
    SLPIEVVLEA | VHKLKYENYT | SSFFIRDIIK | PDPPKNLQLN | PLKNSRHVEI | 
    300:
    SWEYPDTWST | PHSYFSLMFG | VQVQGKNKRE | KKDKLFTDQI | SAKVTCHKDA | 
    324:
    NIRVQARDRY | YSSSWSEWAS | VSCN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Pig IL-12B
    Cat.:
    E0058p
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig IL-12B
    Cat.:
    E0058m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig IL-12B
    Cat.:
    E0058d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig IL-12B
    Cat.:
    E0058b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig IL-12B
    Cat.:
    E0058h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig IL-12B
    Cat.:
    U0058h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig IL-12B
    Cat.:
    U0058b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig IL-12B
    Cat.:
    U0058m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig IL-12B
    Cat.:
    U0058p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig IL-12B
    Cat.:
    U0058d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Pig IL-12B
    Cat.:
    P0058Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig IL-12B
    Polyclonal Antibody for Pig IL-12B
    Polyclonal Antibody for Pig IL-12B
    Polyclonal Antibody for Pig IL-12B
    Cat.:
    P0058Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Pig IL-12B
    Monoclonal Antibody for Pig IL-12B
    Monoclonal Antibody for Pig IL-12B
    Monoclonal Antibody for Pig IL-12B
    Monoclonal Antibody for Pig IL-12B
    Protein for Pig IL-12B
    Protein for Pig IL-12B
    Protein for Pig IL-12B
    Protein for Pig IL-12B
    Protein for Pig IL-12B

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    References
    1. 1.
      "Molecular cloning and mRNA expression of porcine interleukin-12."
      Foss D.L. , Murtaugh M.P.
      Vet. Immunol. Immunopathol.57:121-134(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Spleen.
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