ISG15 ELISA Kit for Human(Homo sapiens) | EIAab.comISG15 ELISA Kit for Human(Homo sapiens) | EIAab.com

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ISG15 (Gene name),

Ubiquitin-like protein ISG15 (Protein name ), ISG15_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Citations (1)

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Gene name:

ISG15(G1P2;UCRP);

Protein name:

Ubiquitin-like protein ISG15;

Alternative:

Interferon-induced 17 kDa protein(IP17);Interferon-induced 15 kDa protein;Ubiquitin cross-reactive protein(hUCRP);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with, and is conjugated to its targets by the UBE1L (E1 enzyme) and UBE2E2 (E2 enzyme) (Probable). Interaction with influenza B NS1 protein inhibits this conjugation.

Function:

In response to IFN-tau secreted by the conceptus, may ligate to and regulate proteins involved in the release of prostaglandin F2-alpha (PGF), and thus prevent lysis of the corpus luteum and maintain the pregnancy.

Subcellular Location:

Cytoplasm Secreted UCRP conjugates seem to be noncovalently associated with the intermediate filaments and distributed in a punctate pattern. Also secreted.

Protein Attributes:

Sequence length:

165

Sequence:

50:

MGWDLTVKML | AGNEFQVSLS | SSMSVSELKA | QITQKIGVHA | FQQRLAVHPS |

100:

GVALQDRVPL | ASQGLGPGST | VLLVVDKCDE | PLSILVRNNK | GRSSTYEVRL |

150:

TQTVAHLKQQ | VSGLEGVQDD | LFWLTFEGKP | LEDQLPLGEY | GLKPLSTVFM |

165:

NLRLRGGGTE | PGGRS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

String:

SMR:

UniGene:

KEGG:

Pfam:

STRING:

9606.ENSP00000368699

Uniprot:

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ELISA Kit for Human Ubiquitin-like protein ISG15

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E14926h

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96T

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ELISA Kit for Human Ubiquitin-like protein ISG15

Cat.:

E14926b

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96T

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ELISA Kit for Human Ubiquitin-like protein ISG15

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E14926m

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96T

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CLIA Kit for Human Ubiquitin-like protein ISG15

Cat.:

U14926m

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96T

CLIA Kit for Human Ubiquitin-like protein ISG15

Cat.:

U14926h

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CLIA Kit for Human Ubiquitin-like protein ISG15

Cat.:

U14926b

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96T

Polyclonal Antibody for Human Ubiquitin-like protein ISG15

Polyclonal Antibody for Human Ubiquitin-like protein ISG15

Polyclonal Antibody for Human Ubiquitin-like protein ISG15

Monoclonal Antibody for Human Ubiquitin-like protein ISG15

Monoclonal Antibody for Human Ubiquitin-like protein ISG15

Monoclonal Antibody for Human Ubiquitin-like protein ISG15

Protein for Human Ubiquitin-like protein ISG15

Protein for Human Ubiquitin-like protein ISG15

Protein for Human Ubiquitin-like protein ISG15

R&D Technical Data

s

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s

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Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤4.9%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤9.3%

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Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤3.9%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.7%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Recovery

Recovery was determined by spiking various levels of ISG15 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	104	96-107
Plasma	103	94-106

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Recovery was determined by spiking various levels of ACE into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	99	91-103
Plasma	98	93-106

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Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ISG15 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	99-108%	98-111%	100-106%	99-109%
EDTA plasma(n=5)	95-111%	97-108%	98-108%	100-107%
heparin plasma(n=5)	98-106%	94-112%	96-109%	98-108%

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	92-105%	90-101%	95-105%	92-109%
EDTA plasma(n=5)	89-95%	93105%	89-94%	90-106%
heparin plasma(n=5)	93-104%	94-110%	101-111%	91-110%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Citations

[1].

"ISG15 promotes Esophageal Squamous Cell Carcinoma tumorigenesis via c-MET/Fyn/β-catenin signaling pathway"

H Yuan, W Zhou, Y Yang, et al.

From:Experimental Cell Research

References

1.

"Molecular characterization of the interferon-induced 15-kDa protein. Molecular cloning and nucleotide and amino acid sequence."
Blomstrom D.C. , Fahey D. , Kutny R. , Korant B.D. , Knight E. Jr.
J. Biol. Chem.261:8811-8816(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element."
Reich N. , Evans B. , Levy D. , Fahey D. , Knight E. Jr. , Darnell J.E. Jr.
Proc. Natl. Acad. Sci. U.S.A.84:6394-6398(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"A 15-kDa interferon-induced protein is derived by COOH-terminal processing of a 17-kDa precursor."
Knight E. Jr. , Fahey D. , Cordova B. , Hillman M. Jr. , Kutny R. , Reich N. , Blomstrom D.C.
J. Biol. Chem.263:4520-4522(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEOLYTIC PROCESSING
4.

Knight E. Jr. , Fahey D. , Cordova B. , Hillman M. Jr. , Kutny R. , Reich N. , Blomstrom D.C.
J. Biol. Chem.263:10040-10040(1988)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
5.

"Conjugation by ubiquitin-like proteins."
Kamitani T. , Fukuda-Kamitani T.
Submitted (2002-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ASN-83
tissue: Testis.
6.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASN-83
7.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASN-83
tissue: Colon.
10.

"A 15-kD interferon-induced protein and its 17-kD precursor: expression in Escherichia coli, purification, and characterization."
Feltham N. , Hillman M. Jr. , Cordova B. , Fahey D. , Larsen B. , Blomstrom D.C. , Knight E. Jr.
J. Interferon Res.9:493-507(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-38 AND 151-165;PROTEOLYTIC PROCESSING
11.

"Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin."
Haas A.L. , Ahrens P. , Bright P.M. , Ankel H.
J. Biol. Chem.262:11315-11323(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SIMILARITY TO UBIQUITIN
12.

"The interferon-inducible 15-kDa ubiquitin homolog conjugates to intracellular proteins."
Loeb K.R. , Haas A.L.
J. Biol. Chem.267:7806-7813(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
13.

"Conjugates of ubiquitin cross-reactive protein distribute in a cytoskeletal pattern."
Loeb K.R. , Haas A.L.
Mol. Cell. Biol.14:8408-8419(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
14.

"Conjugation of the 15-kDa interferon-induced ubiquitin homolog is distinct from that of ubiquitin."
Narasimhan J. , Potter J.L. , Haas A.L.
J. Biol. Chem.271:324-330(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
15.

"IFN-induced 15-kDa protein is released from human lymphocytes and monocytes."
Knight E. Jr. , Cordova B.
J. Immunol.146:2280-2284(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
16.

"Immunohistochemical localization of ubiquitin cross-reactive protein in human tissues."
Lowe J. , McDermott H. , Loeb K. , Landon M. , Haas A.L. , Mayer R.J.
J. Pathol.177:163-169(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
17.

"Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein."
Yuan W. , Krug R.M.
EMBO J.20:362-371(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UBE1L AND INFLUENZA B NS1
18.

"UBP43 (USP18) specifically removes ISG15 from conjugated proteins."
Malakhov M.P. , Malakhova O.A. , Kim K.I. , Ritchie K.J. , Zhang D.-E.
J. Biol. Chem.277:9976-9981(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
19.

"The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein."
Zhao C. , Beaudenon S.L. , Kelley M.L. , Waddell M.B. , Yuan W. , Schulman B.A. , Huibregtse J.M. , Krug R.M.
Proc. Natl. Acad. Sci. U.S.A.101:7578-7582(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UBE2E2
20.

"ISG15 modification of Ubc13 suppresses its ubiquitin-conjugating activity."
Takeuchi T. , Yokosawa H.
Biochem. Biophys. Res. Commun.336:9-13(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN UBE2N ISGYLATION
21.

"Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme."
Takeuchi T. , Iwahara S. , Saeki Y. , Sasajima H. , Yokosawa H.
J. Biochem.138:711-719(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN UBE2E1 AND UBE2L6 ISGYLATION
22.

"Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways."
Zhao C. , Denison C. , Huibregtse J.M. , Gygi S.P. , Krug R.M.
Proc. Natl. Acad. Sci. U.S.A.102:10200-10205(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN IFIT1; DDX58 AND MX1 ISGYLATION
23.

"Negative regulation of protein phosphatase 2Cbeta by ISG15 conjugation."
Takeuchi T. , Kobayashi T. , Tamura S. , Yokosawa H.
FEBS Lett.580:4521-4526(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PPM1B ISGYLATION
24.

"Innate antiviral response targets HIV-1 release by the induction of ubiquitin-like protein ISG15."
Okumura A. , Lu G. , Pitha-Rowe I. , Pitha P.M.
Proc. Natl. Acad. Sci. U.S.A.103:1440-1445(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN HIV-1 RESTRICTION
25.

"Different roles for two ubiquitin-like domains of ISG15 in protein modification."
Chang Y.G. , Yan X.Z. , Xie Y.Y. , Gao X.C. , Song A.X. , Zhang D.E. , Hu H.Y.
J. Biol. Chem.283:13370-13377(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOMAINS UBIQUITIN-LIKE 1 AND 2
26.

"Nitrosylation of ISG15 prevents the disulfide bond-mediated dimerization of ISG15 and contributes to effective ISGylation."
Okumura F. , Lenschow D.J. , Zhang D.E.
J. Biol. Chem.283:24484-24488(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: S-NITROSYLATION AT CYS-78
27.

"ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity."
Okumura A. , Pitha P.M. , Harty R.N.
Proc. Natl. Acad. Sci. U.S.A.105:3974-3979(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN EBOLA VIRUS RESTRICTION;INTERACTION WITH NEDD4
28.

"ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway."
Jeon Y.J. , Choi J.S. , Lee J.Y. , Yu K.R. , Kim S.M. , Ka S.H. , Oh K.H. , Kim K.I. , Zhang D.E. , Bang O.S. , Chung C.H.
EMBO Rep.10:374-380(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN FLNB ISGYLATION
29.

"Antiviral activity of innate immune protein ISG15."
Harty R.N. , Pitha P.M. , Okumura A.
J. Innate Immun.1:397-404(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
30.

"Interferon-induced ISG15 conjugation inhibits influenza A virus gene expression and replication in human cells."
Hsiang T.Y. , Zhao C. , Krug R.M.
J. Virol.83:5971-5977(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN INFLUENZA A VIRUS RESTRICTION
31.

"ISG15 and immune diseases."
Jeon Y.J. , Yoo H.M. , Chung C.H.
Biochim. Biophys. Acta1802:485-496(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
32.

"Emerging role of ISG15 in antiviral immunity."
Skaug B. , Chen Z.J.
Cell143:187-190(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
33.

"The interferon stimulated gene 15 functions as a proviral factor for the hepatitis C virus and as a regulator of the IFN response."
Broering R. , Zhang X. , Kottilil S. , Trippler M. , Jiang M. , Lu M. , Gerken G. , Schlaak J.F.
Gut59:1111-1119(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
34.

"Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification."
Shi H.X. , Yang K. , Liu X. , Liu X.Y. , Wei B. , Shan Y.F. , Zhu L.H. , Wang C.
Mol. Cell. Biol.30:2424-2436(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN IRF3 ISGYLATION
35.

"ISG15 conjugation system targets the viral NS1 protein in influenza A virus-infected cells."
Zhao C. , Hsiang T.Y. , Kuo R.L. , Krug R.M.
Proc. Natl. Acad. Sci. U.S.A.107:2253-2258(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN INFLUENZA A VIRUS NS1 ISGYLATION
36.

"Antiviral properties of ISG15."
Lenschow D.J.
Viruses2:2154-2168(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
37.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
38.

"Interferon-stimulated gene 15 and the protein ISGylation system."
Zhang D. , Zhang D.E.
J. Interferon Cytokine Res.31:119-130(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
39.

"Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15."
Kuang Z. , Seo E.J. , Leis J.
J. Virol.85:7153-7161(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CHMP5; CHMP2A; CHMP4B AND CHMP6 ISGYLATION
40.

"Budding of enveloped viruses: interferon-induced ISG15-antivirus mechanisms targeting the release process."
Seo E.J. , Leis J.
Adv. Virol.2012:532723-532723(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
41.

"IFNs, ISGylation and cancer: Cui prodest?"
Sgorbissa A. , Brancolini C.
Cytokine Growth Factor Rev.23:307-314(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
42.

"Covalent protein modification with ISG15 via a conserved cysteine in the hinge region."
Bade V.N. , Nickels J. , Keusekotten K. , Praefcke G.J.
PLoS ONE7:E38294-E38294(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN UBE2N AND UBA7 ISGYLATION;DISULFIDE BOND
43.

"Mycobacterial disease and impaired IFN-gamma immunity in humans with inherited ISG15 deficiency."
Bogunovic D. , Byun M. , Durfee L.A. , Abhyankar A. , Sanal O. , Mansouri D. , Salem S. , Radovanovic I. , Grant A.V. , Adimi P. , Mansouri N. , Okada S. , Bryant V.L. , Kong X.F. , Kreins A. , Velez M.M. , Boisson B. , Khalilzadeh S. , more...
Science337:1684-1688(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
44.

"ISG15 regulates IFN-? immunity in human mycobacterial disease."
Fan J.B. , Zhang D.E.
Cell Res.23:173-175(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
45.

"ISG15: leading a double life as a secreted molecule."
Bogunovic D. , Boisson-Dupuis S. , Casanova J.L.
Exp. Mol. Med.45:E18-E18(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
46.

"Activation of double-stranded RNA-activated protein kinase (PKR) by interferon-stimulated gene 15 (ISG15) modification down-regulates protein translation."
Okumura F. , Okumura A.J. , Uematsu K. , Hatakeyama S. , Zhang D.E. , Kamura T.
J. Biol. Chem.288:2839-2847(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN EIF2AK2 ISGYLATION
47.

"Interferon-induced ISG15 pathway: an ongoing virus-host battle."
Zhao C. , Collins M.N. , Hsiang T.Y. , Krug R.M.
Trends Microbiol.21:181-186(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
48.

"Crystal structure of the interferon-induced ubiquitin-like protein ISG15."
Narasimhan J. , Wang M. , Fu Z. , Klein J.M. , Haas A.L. , Kim J.J.
J. Biol. Chem.280:27356-27365(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 1-155 OF MUTANT SER-78
49.

"Solution NMR structure of the C-terminal domain of the interferon alpha-inducible ISG15 protein from Homo sapiens."
Northeast structural genomics consortium (NESG)
Submitted (2009-02) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 79-157

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