LIFR ELISA Kit for Human(Homo sapiens) | EIAab.comLIFR ELISA Kit for Human(Homo sapiens)

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Index > Protein center > LIFR(Gene name) > Human

LIFR (Gene name),

Leukemia inhibitory factor receptor (Protein name ), LIFR_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LIFR;

Protein name:

Leukemia inhibitory factor receptor(LIF receptor;LIF-R);

Alternative:

CD:

CD118;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer composed of LIFR and IL6ST. The heterodimer formed by LIFR and IL6ST interacts with the complex formed by CNTF and CNTFR.

Function:

Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

Subcellular Location:

Isoform 2 Secreted

Protein Attributes:

Sequence length:

1097

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1097:

NSEIVSFGSP | CSINSRQFLI | PPKDEDSPKS | NGGGWSFTNF | FQNKPND

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P42702

KEGG:

hsa:3977

STRING:

9606.ENSP00000263409

UniGene:

Hs.133421

MIM:

151443

Pfam:

PF00041

SMR:

P42702

Uniprot:

P42702

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ELISA Kit for Human LIF receptor

Cat.:

E0561h

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96T

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ELISA Kit for Human LIF receptor

Cat.:

E0561d

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ELISA Kit for Human LIF receptor

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E0561r

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96T

ELISA Kit for Human LIF receptor

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E0561m

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96T

CLIA Kit for Human LIF receptor

Cat.:

U0561d

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96T

CLIA Kit for Human LIF receptor

Cat.:

U0561r

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96T

CLIA Kit for Human LIF receptor

Cat.:

U0561m

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96T

CLIA Kit for Human LIF receptor

Cat.:

U0561h

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96T

Polyclonal Antibody for Human LIF receptor

Cat.:

P0561Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human LIF receptor

Cat.:

P0561Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human LIF receptor

Cat.:

P0561Rb-h

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40ug/0.2ml

Monoclonal Antibody for Human LIF receptor

Protein for Human LIF receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130."
Gearing D.P. , Thut C.J. , Vanden Bos T. , Gimpel S.D. , Delaney P.B. , King J. , Price V. , Cosman D. , Beckmann M.P.
EMBO J.10:2839-2848(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Placenta.
2.

"Human LIF receptor 3' non-coding region."
Wang Z. , Melmed S.
Submitted (1996-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 942-1097
3.

"The recurrent translocation t(5;8)(p13;q12) in pleomorphic adenomas results in upregulation of PLAG1 gene expression under control of the LIFR promoter."
Voz M.L. , Astrom A.-K. , Kas K. , Mark J. , Stenman G. , Van de Ven W.J.M.
Oncogene16:1409-1416(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH PLAG1
4.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-927;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
5.

"Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex."
Skiniotis G. , Lupardus P.J. , Martick M. , Walz T. , Garcia K.C.
Mol. Cell31:737-748(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF 52-534;IDENTIFICATION IN A COMPLEX WITH IL6ST; CNTF AND CNTFR;GLYCOSYLATION AT ASN-131; ASN-303; ASN-407 AND ASN-426;DISULFIDE BONDS;ELECTRON MICROSCOPY;SUBUNIT
6.

"Null leukemia inhibitory factor receptor (LIFR) mutations in Stueve-Wiedemann/Schwartz-Jampel type 2 syndrome."
Dagoneau N. , Scheffer D. , Huber C. , Al-Gazali L.I. , Di Rocco M. , Godard A. , Martinovic J. , Raas-Rothschild A. , Sigaudy S. , Unger S. , Nicole S. , Fontaine B. , Taupin J.-L. , Moreau J.-F. , Superti-Furga A. , Le Merrer M. , Bonaventure J. , Munnich A. , more...
Am. J. Hum. Genet.74:298-305(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT STWS PRO-279
7.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] LEU-1068

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