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Index > Protein center > LOXL1(Gene name) > Human
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  • LOXL1 (Gene name),
  • Lysyl oxidase homolog 1 (Protein name ),  LOXL1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LOXL1(LOXL);
    Protein name:
    Lysyl oxidase homolog 1;
    Alternative:
    Lysyl oxidase-like protein 1(LOL);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Active on elastin and collagen substrates.
    Subcellular Location:
    Secreted extracellular space
    Protein Attributes:
    Sequence length:
    574
    Sequence:
    50:
    MALARGSRQL | GALVWGACLC | VLVHGQQAQP | GQGSDPARWR | QLIQWENNGQ | 
    100:
    VYSLLNSGSE | YVPAGPQRSE | SSSRVLLAGA | PQAQQRRSHG | SPRRRQAPSL | 
    150:
    PLPGRVGSDT | VRGQARHPFG | FGQVPDNWRE | VAVGDSTGMA | RARTSVSQQR | 
    200:
    HGGSASSVSA | SAFASTYRQQ | PSYPQQFPYP | QAPFVSQYEN | YDPASRTYDQ | 
    250:
    GFVYYRPAGG | GVGAGAAAVA | SAGVIYPYQP | RARYEEYGGG | EELPEYPPQG | 
    300:
    FYPAPERPYV | PPPPPPPDGL | DRRYSHSLYS | EGTPGFEQAY | PDPGPEAAQA | 
    350:
    HGGDPRLGWY | PPYANPPPEA | YGPPRALEPP | YLPVRSSDTP | PPGGERNGAQ | 
    400:
    QGRLSVGSVY | RPNQNGRGLP | DLVPDPNYVQ | ASTYVQRAHL | YSLRCAAEEK | 
    450:
    CLASTAYAPE | ATDYDVRVLL | RFPQRVKNQG | TADFLPNRPR | HTWEWHSCHQ | 
    500:
    HYHSMDEFSH | YDLLDAATGK | KVAEGHKASF | CLEDSTCDFG | NLKRYACTSH | 
    550:
    TQGLSPGCYD | TYNADIDCQW | IDITDVQPGN | YILKVHVNPK | YIVLESDFTN | 
    574:
    NVVRCNIHYT | GRYVSATNCK | IVQS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    MIM:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Lysyl oxidase homolog 1
    Cat.:
    E0426h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Lysyl oxidase homolog 1
    Cat.:
    E0426b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Lysyl oxidase homolog 1
    Cat.:
    E0426m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lysyl oxidase homolog 1
    Cat.:
    U0426b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lysyl oxidase homolog 1
    Cat.:
    U0426m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lysyl oxidase homolog 1
    Cat.:
    U0426h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Lysyl oxidase homolog 1
    Cat.:
    P0426Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Lysyl oxidase homolog 1
    Polyclonal Antibody for Human Lysyl oxidase homolog 1
    Cat.:
    P0426Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Lysyl oxidase homolog 1
    Monoclonal Antibody for Human Lysyl oxidase homolog 1
    Monoclonal Antibody for Human Lysyl oxidase homolog 1
    Protein for Human Lysyl oxidase homolog 1
    Protein for Human Lysyl oxidase homolog 1
    Protein for Human Lysyl oxidase homolog 1

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

    s

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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤5.9%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤9.9%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Recovery was determined by spiking various levels of LOXL1 into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    94-100

    Plasma

    100

    92-103

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of LOXL1 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    98-105%

    90-105%

    93-102%

    92-109%

    EDTA plasma(n=5)

    95-103%

    98-107%

    96-104%

    93-105%

    heparin plasma(n=5)

    96-102%

     

    94-103%

    90-98%

    97-106%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25."
      Kenyon K. , Modi W.S. , Contente S. , Friedman R.M.
      J. Biol. Chem.268:18435-18437(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT LEU-141
      tissue: Skin fibroblast.
    2. 2.
      "Structure of the human lysyl oxidase-like gene."
      Kenyon K. , Sathya G. , Contente S. , Friedman R.M.
      Submitted (1995-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT LEU-141
      tissue: Placenta.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASP-153
      tissue: Amygdala.
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASP-153
      tissue: Lung.
      tissue: Placenta.
    5. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LEU-141 AND ASP-153;SUSCEPTIBILITY TO XFS
    6. 7.
      "Ancestral LOXL1 variants are associated with pseudoexfoliation in Caucasian Australians but with markedly lower penetrance than in Nordic people."
      Hewitt A.W. , Sharma S. , Burdon K.P. , Wang J.J. , Baird P.N. , Dimasi D.P. , Mackey D.A. , Mitchell P. , Craig J.E.
      Hum. Mol. Genet.17:710-716(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ASSOCIATION OF VARIANTS LEU-141 AND ASP-153 WITH EXFOLIATION SYNDROME;TISSUE SPECIFICITY
    7. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] LEU-141;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 9.
      "Association of LOXL1 gene with Finnish exfoliation syndrome patients."
      Lemmela S. , Forsman E. , Onkamo P. , Nurmi H. , Laivuori H. , Kivela T. , Puska P. , Heger M. , Eriksson A. , Forsius H. , Jarvela I.
      J. Hum. Genet.54:289-297(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ASSOCIATION OF VARIANTS LEU-141 AND ASP-153 WITH EXFOLIATION SYNDROME
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