Protein name:
Macrophage metalloelastase (MME) ;
Alternative:
Matrix metalloproteinase-12 (MMP-12) ;Macrophage elastase (ME;hME) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MKFLLILLLQ | ATASGALPLN | SSTSLEKNNV | LFGERYLEKF | YGLEINKLPV |
100:
TKMKYSGNLM | KEKIQEMQHF | LGLKVTGQLD | TSTLEMMHAP | RCGVPDVHHF |
150:
REMPGGPVWR | KHYITYRINN | YTPDMNREDV | DYAIRKAFQV | WSNVTPLKFS |
200:
KINTGMADIL | VVFARGAHGD | FHAFDGKGGI | LAHAFGPGSG | IGGDAHFDED |
250:
EFWTTHSGGT | NLFLTAVHEI | GHSLGLGHSS | DPKAVMFPTY | KYVDINTFRL |
300:
SADDIRGIQS | LYGDPKENQR | LPNPDNSEPA | LCDPNLSFDA | VTTVGNKIFF |
350:
FKDRFFWLKV | SERPKTSVNL | ISSLWPTLPS | GIEAAYEIEA | RNQVFLFKDD |
400:
KYWLISNLRP | EPNYPKSIHS | FGFPNFVKKI | DAAVFNPRFY | RTYFFVDNQY |
450:
WRYDERRQMM | DPGYPKLITK | NFQGIGPKID | AVFYSKNKYY | YFFQGSNQFE |
470:
YDFLLQRITK | TLKSNSWFGC |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rabbit
Rat
Polyclonal Antibody for Human MME
Polyclonal Antibody for Human MME
Polyclonal Antibody for Human MME
Polyclonal Antibody for Human MME
Monoclonal Antibody for Human MME
Monoclonal Antibody for Human MME
Monoclonal Antibody for Human MME
Monoclonal Antibody for Human MME
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
I Gilowska, E Majorczyk, K Bogacz, et al.
[2].
Mirang Kim, Hyun Ja Kim, Bo Youl Choi, Jeong-Hwan Kim, Kyu-Sang Song, Seung-Moo Noh, Jin Cheon Kim, Dong Soo Han, Seon-Young Kim, Yong Sung Kim
[3].
Y Song, Y Xie, F Liu, et al.
References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Alveolar macrophage .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-357 AND ARG-469
3.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Esophagus .
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-357
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.09 ANGSTROMS) OF 106-263
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 100-280