Gene name:
Mmp12 (Mme;Mmel) ;
Protein name:
Macrophage metalloelastase (MME) ;
Alternative:
Matrix metalloproteinase-12 (MMP-12) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MSCTLLKGVC | TMKFLMMIVF | LQVSACGAAP | MNDSEFAEWY | LSRFYDYGKD |
100:
RIPMTKTKTN | RNFLKEKLQE | MQQFFGLEAT | GQLDNSTLAI | MHIPRCGVPD |
150:
VQHLRAVPQR | SRWMKRYLTY | RIYNYTPDMK | REDVDYIFQK | AFQVWSDVTP |
200:
LRFRKLHKDE | ADIMILFAFG | AHGDFNYFDG | KGGTLAHAFY | PGPGIQGDAH |
250:
FDEAETWTKS | FQGTNLFLVA | VHELGHSLGL | QHSNNPKSIM | YPTYRYLNPS |
300:
TFRLSADDIR | NIQSLYGAPV | KPPSLTKPSS | PPSTFCHQSL | SFDAVTTVGE |
350:
KIFFFKDWFF | WWKLPGSPAT | NITSISSIWP | SIPSGIQAAY | EIESRNQLFL |
400:
FKDEKYWLIN | NLVPEPHYPR | SIYSLGFSAS | VKKVDAAVFD | PLRQKVYFFV |
450:
DKHYWRYDVR | QELMDPAYPK | LISTHFPGIK | PKIDAVLYFK | RHYYIFQGAY |
473:
QLEYDPLFRR | VTKTLKSTSW | FGC
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rabbit
Rat
Polyclonal Antibody for Mouse MME
Polyclonal Antibody for Mouse MME
Polyclonal Antibody for Mouse MME
Polyclonal Antibody for Mouse MME
Monoclonal Antibody for Mouse MME
Monoclonal Antibody for Mouse MME
Monoclonal Antibody for Mouse MME
Monoclonal Antibody for Mouse MME
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 110-136
tissue :
Macrophage .
2.
"The transcriptional landscape of the mammalian genome."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
BALB/c .
strain :
C57BL/6J .
strain :
NOD .
tissue :
B-cell .
tissue :
Dendritic cell .
tissue :
Macrophage .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Czech II .
tissue :
Mammary gland .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 11-473