Protein name:
Matrix metalloproteinase-16 (MMP-16) ;
Alternative:
Membrane-type-3 matrix metalloproteinase (MT3-MMP;MT3MMP) ;Membrane-type matrix metalloproteinase 3 (MT-MMP 3;MTMMP3) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with CSPG4 through CSPG4 chondroitin sulfate glycosaminoglycan.
Function:
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Extracellular side
Localized at the cell surface of melanoma cells.
Protein Attributes:
50:
MILLAFSSGR | RLDFVHRSGV | FFLQTLLWIL | CATVCGTEQY | FNVEVWLQKY |
100:
GYLPPTDPRM | SVLRSAETMQ | SALAAMQQFY | GINMTGKVDR | NTIDWMKKPR |
150:
CGVPDQTRGS | SKFNIRRKRY | ALTGQKWQHK | HITYSIKNVT | PKVGDPETRR |
200:
AIRRAFDVWQ | NVTPLTFEEV | PYSELENGKR | DVDITIIFAS | GFHGDSSPFD |
250:
GEGGFLAHAY | FPGPGIGGDT | HFDSDEPWTL | GNPNHDGNDL | FLVAVHELGH |
300:
ALGLEHSNDP | TAIMAPFYQY | METDNFKLPN | DDLQGIQKIY | GPPDKIPPPT |
350:
RPLPTVPPHR | SVPPADPRRH | DRPKPPRPPT | GRPSYPGAKP | NICDGNFNTL |
400:
AILRREMFVF | KDQWFWRVRN | NRVMDGYPMQ | ITYFWRGLPP | SIDAVYENSD |
450:
GNFVFFKGNK | YWVFKDTTLQ | PGYPHDLITL | GNGIPPHGID | SAIWWEDVGK |
500:
TYFFKGDRYW | RYSEEMKTMD | PGYPKPITIW | KGIPESPQGA | FVHKENGFTY |
550:
FYKGKEYWKF | NNQILKVEPG | YPRSILKDFM | GCDGPTDRDK | EGLSPPDDVD |
600:
IVIKLDNTAS | TVKAIAIVIP | CILALCLLVL | VYTVFQFKRK | GTPRHILYCK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse MMP-16
ELISA Kit for Mouse MMP-16
ELISA Kit for Mouse MMP-16
CLIA Kit for Mouse MMP-16
CLIA Kit for Mouse MMP-16
CLIA Kit for Mouse MMP-16
Polyclonal Antibody for Mouse MMP-16
Polyclonal Antibody for Mouse MMP-16
Polyclonal Antibody for Mouse MMP-16
Monoclonal Antibody for Mouse MMP-16
Monoclonal Antibody for Mouse MMP-16
Monoclonal Antibody for Mouse MMP-16
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 .
tissue :
Brain .
3.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
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more...
PLoS Biol.7:E1000112-E1000112(2009)
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
129 .
tissue :
Mammary tumor .