Gene name:
Mmp24 (Mt5mmp) ;
Protein name:
Matrix metalloproteinase-24 (MMP-24) ;
Alternative:
Membrane-type-5 matrix metalloproteinase (MT5-MMP;MT5MMP) ;Membrane-type matrix metalloproteinase 5 (MT-MMP 5;MTMMP5) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Activates progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin.
Subcellular Location:
Processed matrix metalloproteinase-24
Secreted
extracellular space
extracellular matrix
Also shed from cell surface as soluble proteinase, by a proteolytic cleavage.
Protein Attributes:
50:
MPRSRGGRAA | PGQAARWSGW | RAPGRLLPLL | PALCCLAAAA | GAGKPAGADA |
100:
PFAGQNWLKS | YGYLLPYESR | ASALHSGKAL | QSAVSTMQQF | YGIPVTGVLD |
150:
QTTIEWMKKP | RCGVPDHPHL | SRRRRNKRYA | LTGQKWRQKH | ITYSIHNYTP |
200:
KVGELDTRKA | IRQAFDVWQK | VTPLTFEEVP | YHEIKSDRKE | ADIMIFFASG |
250:
FHGDSSPFDG | EGGFLAHAYF | PGPGIGGDTH | FDSDEPWTLG | NANHDGNDLF |
300:
LVAVHELGHA | LGLEHSNDPS | AIMAPFYQYM | ETHNFKLPQD | DLQGIQKIYG |
350:
PPAEPLEPTR | PLPTLPVRRI | HSPSERKHER | QPRPPRPPLG | DRPSTPGAKP |
400:
NICDGNFNTV | ALFRGEMFVF | KDRWFWRLRN | NRVQEGYPMQ | IEQFWKGLPA |
450:
RIDAAYERAD | GRFVFFKGDK | YWVFKEVTVE | PGYPHSLGEL | GSCLPREGID |
500:
TALRWEPVGK | TYFFKGERYW | RYSEERRATD | PGYPKPITVW | KGIPQAPQGA |
550:
FISKEGYYTY | FYKGRDYWKF | DNQKLSVEPG | YPRNILRDWM | GCKQKEVERR |
600:
KERRLPQDDV | DIMVTIDDVP | GSVNAVAVVV | PCTLSLCLLV | LLYTIFQFKN |
618:
KTGPQPVTYY | KRPVQEWV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Polyclonal Antibody for Rat MMP-24
Polyclonal Antibody for Rat MMP-24
Polyclonal Antibody for Rat MMP-24
Monoclonal Antibody for Rat MMP-24
Monoclonal Antibody for Rat MMP-24
Monoclonal Antibody for Rat MMP-24
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Molecular cloning and characterization of rat MT5-MMP."
Sekine-Aizawa Y.
Submitted (1999-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;PROTEOLYTIC PROCESSING;INTERACTION WITH GRIP1 AND GRIP2;MUTAGENESIS OF 616-GLU--VAL-618