Nitric oxide synthase, brain (Protein name
), NOS1_RABIT from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Gene name:
NOS1;
Protein name:
Nitric oxide synthase, brain;
Alternative:
NC-NOS;Constitutive NOS;Neuronal NOS(N-NOS;nNOS);NOS type I;bNOS;Peptidyl-cysteine S-nitrosylase NOS1;
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
Homodimer. Interacts with DLG4; the interaction possibly being prevented by the association between NOS1 and CAPON. Forms a ternary complex with CAPON and RASD1. Forms a ternary complex with CAPON and SYN1. Interacts with ZDHHC23. Interacts with NOSIP; which may impair its synaptic location (By similarity). Interacts with HTR4. Interacts with VAC14 (By similarity). Interacts with SLC6A4.
Function:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Subcellular Location:
Cell membrane
sarcolemma
Peripheral membrane protein
Cell projection
dendritic spine
In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines.
Monoclonal Antibody for Rabbit Nitric oxide synthase, brain
Monoclonal Antibody for Rabbit Nitric oxide synthase, brain
Monoclonal Antibody for Rabbit Nitric oxide synthase, brain
Monoclonal Antibody for Rabbit Nitric oxide synthase, brain
Protein for Rabbit Nitric oxide synthase, brain
Protein for Rabbit Nitric oxide synthase, brain
Protein for Rabbit Nitric oxide synthase, brain
Protein for Rabbit Nitric oxide synthase, brain
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Molecular cloning of a cDNA encoding a constitutive nitric oxide synthase from rabbit brain." Jeong Y.
,
Yim J.
Submitted (1997-02) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [MRNA]