Gene name:
SPP1 (PSEC0156;BNSP;OPN) ;
Protein name:
Osteopontin ;
Alternative:
Nephropontin ;Bone sialoprotein 1 ;Urinary stone protein ;Secreted phosphoprotein 1 (SPP-1) ;Uropontin ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Ligand for integrin alpha-V/beta-3.
Function:
Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
Subcellular Location:
Secreted
Protein Attributes:
50:
MRIAVICFCL | LGITCAIPVK | QADSGSSEEK | QLYNKYPDAV | ATWLNPDPSQ |
100:
KQNLLAPQNA | VSSEETNDFK | QETLPSKSNE | SHDHMDDMDD | EDDDDHVDSQ |
150:
DSIDSNDSDD | VDDTDDSHQS | DESHHSDESD | ELVTDFPTDL | PATEVFTPVV |
200:
PTVDTYDGRG | DSVVYGLRSK | SKKFRRPDIQ | YPDATDEDIT | SHMESEELNG |
250:
AYKAIPVAQD | LNAPSDWDSR | GKDSYETSQL | DDQSAETHSH | KQSRLYKRKA |
300:
NDESNEHSDV | IDSQELSKVS | REFHSHEFHS | HEDMLVVDPK | SKEEDKHLKF |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rabbit
Mouse
Rat
Bovine
Chicken
Pig
ELISA Kit for Human Osteopontin
ELISA Kit for Human Osteopontin
ELISA Kit for Human Osteopontin
ELISA Kit for Human Osteopontin
ELISA Kit for Human Osteopontin
ELISA Kit for Human Osteopontin
ELISA Kit for Human Osteopontin
CLIA Kit for Human Osteopontin
CLIA Kit for Human Osteopontin
CLIA Kit for Human Osteopontin
CLIA Kit for Human Osteopontin
CLIA Kit for Human Osteopontin
CLIA Kit for Human Osteopontin
CLIA Kit for Human Osteopontin
Polyclonal Antibody for Human Osteopontin
Polyclonal Antibody for Human Osteopontin
Polyclonal Antibody for Human Osteopontin
Polyclonal Antibody for Human Osteopontin
Polyclonal Antibody for Human Osteopontin
Polyclonal Antibody for Human Osteopontin
Polyclonal Antibody for Human Osteopontin
Monoclonal Antibody for Human Osteopontin
Monoclonal Antibody for Human Osteopontin
Monoclonal Antibody for Human Osteopontin
Monoclonal Antibody for Human Osteopontin
Monoclonal Antibody for Human Osteopontin
Monoclonal Antibody for Human Osteopontin
Monoclonal Antibody for Human Osteopontin
Protein for Human Osteopontin
Protein for Human Osteopontin
Protein for Human Osteopontin
Protein for Human Osteopontin
Protein for Human Osteopontin
Protein for Human Osteopontin
Protein for Human Osteopontin
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
Monika M, Daniel L, Krzysztof A.T, et al.
[2].
M. Alicka, P. Sobierajska, K. Kornicka, et al.
[3].
S. G. Gaoya, K. H. Liya, K. B. Zengyz, M. Tuyx, M. Xuy and G. H. Lei
[4].
MAA El-Moneim, KF Sayed, AFA Elaziz, et al.
[5].
Yang J, Cao C, Wang W, et al.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM B)
3.
"Inhibition of calcium oxalate crystal growth in vitro by uropontin: another member of the aspartic acid-rich protein superfamily."
Shiraga H.
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Min W.
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Proc. Natl. Acad. Sci. U.S.A.89:426-430(1992)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A)
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM A)
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM A)
tissue :
Liver .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A; B AND C)
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B)
tissue :
Brain .
8.
"Osteopontin splice variants in Indian breast cancer patients as biomarker."
Sivakumar S.
,
Niranjali Devaraj S.
Submitted (2011-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM C)
9.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T.
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more...
Nat. Genet.36:40-45(2004)
[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS A; C AND 5)
tissue :
Kidney .
tissue :
Subthalamic nucleus .
10.
"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
Otsuki T.
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DNA Res.12:117-126(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM D)
tissue :
Placenta .
11.
"A computer system platform used to predict novel genes."
Yu Z.
,
Zheng Z.
,
Tang T.
,
Fu Y.
Submitted (2006-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A)
12.
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W.
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Graves T.A.
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Fulton R.S.
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Fulton L.A.
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Pepin K.H.
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Wang C.
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Osborne J.
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Meyer R.
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Sabo A.
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Shotland Y.
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Wohldmann P.E.
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Cook L.L.
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Warren W.C.
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Chinwalla A.T.
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Eddy S.R.
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Marra M.A.
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Miller W.
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Torrents D.
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Waterston R.H.
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Wilson R.K.
more...
Nature434:724-731(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
13.
Mural R.J.
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Eichler E.E.
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Adams M.D.
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Hunkapiller M.W.
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Myers E.W.
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Venter J.C.
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Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
14.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS A; B AND C)
tissue :
Brain .
tissue :
Kidney .
15.
"Molecular cloning and sequencing of cDNA encoding urinary stone protein, which is identical to osteopontin."
Kohri K.
,
Suzuki Y.
,
Yoshida K.
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Yamamoto K.
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Amasaki N.
,
Yamate T.
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Umekawa T.
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Iguchi M.
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Sinohara H.
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Kurita T.
Biochem. Biophys. Res. Commun.184:859-864(1992)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 67-278
tissue :
Kidney .
16.
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Cited for : PROTEIN SEQUENCE OF 17-23 AND 169-182
tissue :
Milk .
17.
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Cited for : PHOSPHORYLATION AT SER-24; SER-26; SER-27; SER-62; SER-63; THR-66; SER-76; SER-81; SER-99; SER-102; SER-108; SER-117; SER-120; SER-123; SER-129; THR-185; SER-191; SER-195; SER-215; SER-219; SER-224; SER-228; SER-234; SER-254; SER-263; SER-267; SER-275; SER-280; SER-303; SER-308; SER-310; SER-105 AND SER-126;GLYCOSYLATION AT ASN-79; ASN-106; THR-134; THR-138; THR-143; THR-147 AND THR-152
tissue :
Milk .
18.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-81;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Pituitary .
19.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V.
,
Vermeulen M.
,
Santamaria A.
,
Kumar C.
,
Miller M.L.
,
Jensen L.J.
,
Gnad F.
,
Cox J.
,
Jensen T.S.
,
Nigg E.A.
,
Brunak S.
,
Mann M.
Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
20.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-219; SER-224; SER-234 AND SER-254;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.
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Cited for : PHOSPHORYLATION BY FAM20C
22.
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Cited for : GLYCOSYLATION;IDENTIFICATION BY MASS SPECTROMETRY