POU5F1 ELISA Kit for Human(Homo sapiens) | EIAab.comPOU5F1 ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > POU5F1(Gene name) > Human

POU5F1 (Gene name),

POU domain, class 5, transcription factor 1 (Protein name ), PO5F1_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

POU5F1(OCT3;OCT4;OTF3);

Protein name:

POU domain, class 5, transcription factor 1;

Alternative:

Octamer-binding protein 4(Oct-4);Octamer-binding protein 3(Oct-3);Octamer-binding transcription factor 3(OTF-3);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with UBE2I and ZSCAN10 (By similarity). Interacts with PKM2. Interacts with WWP2.

Function:

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Subcellular Location:

Nucleus Expressed in a diffuse and slightly punctuate pattern.

Protein Attributes:

Sequence length:

360

Sequence:

50:

100:

150:

200:

250:

300:

350:

360:

TTLGSPMHSN |

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

Q01860

KEGG:

hsa:5460

MIM:

164177

String:

Q01860

Pfam:

PF00046

UniGene:

Hs.249184

Uniprot:

Q01860

FOR

ELISA Kit for Human POU domain, class 5, transcription factor 1

Cat.:

E1533m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human POU domain, class 5, transcription factor 1

Cat.:

E1533h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human POU domain, class 5, transcription factor 1

Cat.:

E1533b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human POU domain, class 5, transcription factor 1

Cat.:

E1533p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human POU domain, class 5, transcription factor 1

Cat.:

U1533b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human POU domain, class 5, transcription factor 1

Cat.:

U1533h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human POU domain, class 5, transcription factor 1

Cat.:

U1533m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human POU domain, class 5, transcription factor 1

Cat.:

U1533p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human POU domain, class 5, transcription factor 1

Cat.:

P1533Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human POU domain, class 5, transcription factor 1

Cat.:

P1533Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human POU domain, class 5, transcription factor 1

Monoclonal Antibody for Human POU domain, class 5, transcription factor 1

Protein for Human POU domain, class 5, transcription factor 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues."
Takeda J. , Seino S. , Bell G.I.
Nucleic Acids Res.20:4613-4620(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A AND B);VARIANTS ALA-322 AND LEU-357;TISSUE SPECIFICITY
tissue: Kidney.
2.

"Comparison of MHC class I risk haplotypes in Thai and Caucasian psoriatics shows locus heterogeneity at PSORS1."
Stuart P.E. , Nair R.P. , Hiremagalore R. , Kullavanijaya P. , Kullavanijaya P. , Tejasvi T. , Lim H.W. , Voorhees J.J. , Elder J.T.
Tissue Antigens76:387-397(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Blood.
3.

"Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity."
Shiina T. , Ota M. , Shimizu S. , Katsuyama Y. , Hashimoto N. , Takasu M. , Anzai T. , Kulski J.K. , Kikkawa E. , Naruse T. , Kimura N. , Yanagiya K. , Watanabe A. , Hosomichi K. , Kohara S. , Iwamoto C. , Umehara Y. , Meyer A. , more...
Genetics173:1555-1570(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Peripheral blood leukocyte.
4.

"Homo sapiens 2,229,817bp genomic DNA of 6p21.3 HLA class I region."
Shiina S. , Tamiya G. , Oka A. , Inoko H.
Submitted (1999-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The DNA sequence and analysis of human chromosome 6."
Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
8.

"A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues."
Wey E. , Lyons G.E. , Schaefer B.W.
Eur. J. Biochem.220:753-762(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 188-274;TISSUE SPECIFICITY
tissue: Heart.
tissue: Skeletal muscle.
9.

"Expression of transcription regulating genes in human preimplantation embryos."
Abdel-Rahman B. , Fiddler M. , Rappolee D. , Pergament E.
Hum. Reprod.10:2787-2792(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 212-283
10.

"Oct4 pseudogenes are transcribed in cancers."
Suo G. , Han J. , Wang X. , Zhang J. , Zhao Y. , Zhao Y. , Dai J.
Biochem. Biophys. Res. Commun.337:1047-1051(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
11.

"Induction of pluripotent stem cells from adult human fibroblasts by defined factors."
Takahashi K. , Tanabe K. , Ohnuki M. , Narita M. , Ichisaka T. , Tomoda K. , Yamanaka S.
Cell131:861-872(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: BIOTECHNOLOGY;FUNCTION
12.

"Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription."
Lee J. , Kim H.K. , Han Y.-M. , Kim J.
Int. J. Biochem. Cell Biol.40:1043-1054(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PKM;SUBCELLULAR LOCATION;DOMAIN;INDUCTION
13.

"WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells."
Xu H. , Wang W. , Li C. , Yu H. , Yang A. , Wang B. , Jin Y.
Cell Res.19:561-573(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION;SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE;INTERACTION WITH WWP2
14.

"Serine 111 phosphorylation regulates OCT4A protein subcellular distribution and degradation."
Spelat R. , Ferro F. , Curcio F.
J. Biol. Chem.287:38279-38288(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-111;SUBCELLULAR LOCATION
15.

"Phosphorylation regulates human OCT4."
Brumbaugh J. , Hou Z. , Russell J.D. , Howden S.E. , Yu P. , Ledvina A.R. , Coon J.J. , Thomson J.A.
Proc. Natl. Acad. Sci. U.S.A.109:7162-7168(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-111; THR-235; SER-236; SER-289; SER-290 AND SER-355

Product Feedback Wall

* Email:
*Comments: