Acpp ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAcpp ELISA Kit for Rat(Rattus norvegicus)

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Acpp (Gene name),

Prostatic acid phosphatase (Protein name ), PPAP_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Acpp;

Protein name:

Prostatic acid phosphatase;

Alternative:

Ecto-5'-nucleotidase;3.1.3.5;5'-nucleotidase(5'-NT);Thiamine monophosphatase(TMPase);Fluoride-resistant acid phosphatase(FRAP);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer; dimer formation is required for phosphatase activity.

Function:

Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor.

Subcellular Location:

Isoform 2 Cell membrane Single-pass type I membrane protein Lysosome membrane Single-pass type I membrane protein Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles. Colocalizes with LAMP2 on the lysosome membrane.

Protein Attributes:

Sequence length:

381

Sequence:

50:

100:

150:

200:

250:

300:

350:

381:

PLEKFAELLD | PVIPQDWATE | CMGTSNHQAS | L

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00328

String:

P20646

KEGG:

rno:56780

STRING:

10116.ENSRNOP00000016222

UniGene:

Rn.40121

SMR:

P20646

Uniprot:

P20646

FOR

ELISA Kit for Rat Prostatic acid phosphatase

Cat.:

E0168r

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96T

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ELISA Kit for Rat Prostatic acid phosphatase

Cat.:

E0168h

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96T

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ELISA Kit for Rat Prostatic acid phosphatase

Cat.:

E0168m

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96T

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ELISA Kit for Rat Prostatic acid phosphatase

Cat.:

E0168b

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Packing:

96T

CLIA Kit for Rat Prostatic acid phosphatase

Cat.:

U0168b

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MSDS:

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Packing:

96T

CLIA Kit for Rat Prostatic acid phosphatase

Cat.:

U0168r

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Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rat Prostatic acid phosphatase

Cat.:

U0168m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Prostatic acid phosphatase

Cat.:

U0168h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Prostatic acid phosphatase

Cat.:

P0168Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Prostatic acid phosphatase

Cat.:

P0168Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Prostatic acid phosphatase

Cat.:

P0168Rb-h

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40ug/0.2ml

Monoclonal Antibody for Rat Prostatic acid phosphatase

Protein for Rat Prostatic acid phosphatase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Primary structure of rat secretory acid phosphatase and comparison to other acid phosphatases."
Roiko K. , Jaenne O.A. , Vihko P.
Gene89:223-229(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Prostate.
2.

"Prostatic acid phosphatase is not a prostate specific target."
Quintero I.B. , Araujo C.L. , Pulkka A.E. , Wirkkala R.S. , Herrala A.M. , Eskelinen E.-L. , Jokitalo E. , Hellstroem P.A. , Tuominen H.J. , Hirvikoski P.P. , Vihko P.T.
Cancer Res.67:6549-6554(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
strain: Sprague-Dawley.
3.

"The localization of fluoride-resistant acid phosphatase (FRAP) in the pelvic nerves and sacral spinal cord of rats."
McMahon S.B.
Neurosci. Lett.64:305-310(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
4.

"Site-directed mutagenesis of prostatic acid phosphatase. Catalytically important aspartic acid 258, substrate specificity, and oligomerization."
Porvari K.S. , Herrala A.M. , Kurkela R.M. , Taavitsainen P.A. , Lindqvist Y. , Schneider G. , Vihko P.T.
J. Biol. Chem.269:22642-22646(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACTIVE SITE;SUBUNIT;ENZYME REGULATION;SUBSTRATE SPECIFICITY;MUTAGENESIS OF TRP-137; HIS-143; TYR-154; ARG-158 AND ASP-289
5.

"Prostatic acid phosphatase is expressed in peptidergic and nonpeptidergic nociceptive neurons of mice and rats."
Taylor-Blake B. , Zylka M.J.
PLoS ONE5:E8674-E8674(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
6.

"Three-dimensional structure of rat acid phosphatase."
Schneider G. , Lindqvist Y. , Vihko P.
EMBO J.12:2609-2615(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS);SUBUNIT;GLYCOSYLATION AT ASN-93 AND ASN-332
7.

"Three-dimensional structure of rat acid phosphatase in complex with L(+)-tartrate."
Lindqvist Y. , Schneider G. , Vihko P.
J. Biol. Chem.268:20744-20746(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) IN COMPLEX WITH L(+)-TARTRATE;GLYCOSYLATION AT ASN-93 AND ASN-332

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