PRDX6 ELISA Kit for Human(Homo sapiens) | EIAab.comPRDX6 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PRDX6(Gene name) > Human

PRDX6 (Gene name),

Peroxiredoxin-6 (Protein name ), PRDX6_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (2)

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Gene name:

PRDX6(AOP2;KIAA0106);

Protein name:

Peroxiredoxin-6;

Alternative:

24 kDa protein;1-Cys peroxiredoxin(1-Cys PRX);Antioxidant protein 2;3.1.1.-;Acidic calcium-independent phospholipase A2(aiPLA2);1.11.1.9;Non-selenium glutathione peroxidase(NSGPx);Liver 2D page spot 40;Red blood cells page spot 12;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotetramer. Interacts with GSTP1; mediates PRDX6 glutathionylation and regeneration. May interact with HTR2A (By similarity). Interacts with APEX1 and STH.

Function:

Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Subcellular Location:

Cytoplasm Lysosome Cytoplasmic vesicle Also found in lung secretory organelles.

Protein Attributes:

Sequence length:

224

Sequence:

50:

100:

150:

200:

224:

LFPKGVFTKE | LPSGKKYLRY | TPQP

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000342026

KEGG:

hsa:9588

Pfam:

PF10417

SMR:

P30041

String:

P30041

MIM:

602316

UniGene:

Hs.120

Uniprot:

P30041

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ELISA Kit for Human Peroxiredoxin-6

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E1751h

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96T

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ELISA Kit for Human Peroxiredoxin-6

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E1751r

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96T

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ELISA Kit for Human Peroxiredoxin-6

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E1751c

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96T

ELISA Kit for Human Peroxiredoxin-6

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E1751b

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96T

ELISA Kit for Human Peroxiredoxin-6

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E1751p

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96T

ELISA Kit for Human Peroxiredoxin-6

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E1751m

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96T

CLIA Kit for Human Peroxiredoxin-6

Cat.:

U1751r

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96T

CLIA Kit for Human Peroxiredoxin-6

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U1751b

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96T

CLIA Kit for Human Peroxiredoxin-6

Cat.:

U1751p

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Packing:

96T

CLIA Kit for Human Peroxiredoxin-6

Cat.:

U1751h

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Looking for manual.

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96T

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CLIA Kit for Human Peroxiredoxin-6

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U1751c

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96T

CLIA Kit for Human Peroxiredoxin-6

Cat.:

U1751m

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96T

Polyclonal Antibody for Human Peroxiredoxin-6

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P1751Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Peroxiredoxin-6

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P1751Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Peroxiredoxin-6

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P1751Rb-r

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Polyclonal Antibody for Human Peroxiredoxin-6

Monoclonal Antibody for Human Peroxiredoxin-6

Protein for Human Peroxiredoxin-6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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Citations

[1].

"Novel links among peroxiredoxins, endothelial dysfunction, and severity of atherosclerosis in type 2 diabetic patients with peripheral atherosclerotic"

E El Eter, A Al Masri, S Habib, H Al Zamil, A AI Hersi, F AI Hussein, M AI Omran

From:Cell Stress and Chaperones

[2].

"Peroxiredoxin isoforms are associated with cardiovascular risk factors in type 2 diabetes mellitus"

E El Eter, AA Al-Masri

From:Brazilian Journal of Medical and Biological Research

References

1.

"Identification of a human cDNA clone for lysosomal type Ca2+-independent phospholipase A2 and properties of the expressed protein."
Kim T.-S. , Sundaresh C.S. , Feinstein S.I. , Dodia C. , Skach W.R. , Jain M.K. , Nagase T. , Seki N. , Ishikawa K. , Nomura N. , Fisher A.B.
J. Biol. Chem.272:2542-2550(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

Kim T.-S. , Sundaresh C.S. , Feinstein S.I. , Dodia C. , Skach W.R. , Jain M.K. , Nagase T. , Seki N. , Ishikawa K. , Nomura N. , Fisher A.B.
J. Biol. Chem.272:10981-10981(1997)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
3.

"The human homologue of a bovine non-selenium glutathione peroxidase is a novel keratinocyte growth factor-regulated gene."
Frank S. , Munz B. , Werner S.
Oncogene14:915-921(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1."
Nagase T. , Miyajima N. , Tanaka A. , Sazuka T. , Seki N. , Sato S. , Tabata S. , Ishikawa K. , Kawarabayasi Y. , Kotani H. , Nomura N.
DNA Res.2:37-43(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Bone marrow.
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
6.

NIEHS SNPs program
Submitted (2005-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Fetal brain.
tissue: Testis.
10.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-22
tissue: Platelet.
11.

Lubec G. , Vishwanath V. , Chen W.-Q. , Sun Y.
Submitted (2008-12) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-22; 25-53; 85-106; 133-142; 145-155; 163-173 AND 175-199;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Brain.
tissue: Cajal-Retzius cell.
tissue: Fetal brain cortex.
12.

"Human liver protein map: a reference database established by microsequencing and gel comparison."
Hochstrasser D.F. , Frutiger S. , Paquet N. , Bairoch A. , Ravier F. , Pasquali C. , Sanchez J.-C. , Tissot J.-D. , Bjellqvist B. , Vargas R. , Appel R.D. , Hughes G.J.
Electrophoresis13:992-1001(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-15
tissue: Liver.
13.

"Plasma and red blood cell protein maps: update 1993."
Golaz O. , Hughes G.J. , Frutiger S. , Paquet N. , Bairoch A. , Pasquali C. , Sanchez J.-C. , Tissot J.-D. , Appel R.D. , Walzer C. , Balant L. , Hochstrasser D.F.
Electrophoresis14:1223-1231(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-13
tissue: Erythrocyte.
14.

"DNA probes built and sequenced for microarrays hybridisations."
Dominguez O. , Lombardia L.
Submitted (2004-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 14-99
15.

"Characterization of a mammalian peroxiredoxin that contains one conserved cysteine."
Kang S.W. , Baines I.C. , Rhee S.G.
J. Biol. Chem.273:6303-6311(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION;MUTAGENESIS
16.

"1-Cys peroxiredoxin, a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities."
Chen J.-W. , Dodia C. , Feinstein S.I. , Jain M.K. , Fisher A.B.
J. Biol. Chem.275:28421-28427(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION;MUTAGENESIS
17.

"A method for detection of overoxidation of cysteines: peroxiredoxins are oxidized in vivo at the active-site cysteine during oxidative stress."
Wagner E. , Luche S. , Penna L. , Chevallet M. , van Dorsselaer A. , Leize-Wagner E. , Rabilloud T.
Biochem. J.366:777-785(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: OVEROXIDATION AT CYS-47
18.

"Saitohin, which is nested in the tau locus and confers allele-specific susceptibility to several neurodegenerative diseases, interacts with peroxiredoxin 6."
Gao L. , Tse S.-W. , Conrad C. , Andreadis A.
J. Biol. Chem.280:39268-39272(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH STH
19.

"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
Rush J. , Moritz A. , Lee K.A. , Guo A. , Goss V.L. , Spek E.J. , Zhang H. , Zha X.-M. , Polakiewicz R.D. , Comb M.J.
Nat. Biotechnol.23:94-101(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-89;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
20.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-44;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
21.

"APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process."
Vascotto C. , Fantini D. , Romanello M. , Cesaratto L. , Deganuto M. , Leonardi A. , Radicella J.P. , Kelley M.R. , D'Ambrosio C. , Scaloni A. , Quadrifoglio F. , Tell G.
Mol. Cell. Biol.29:1834-1854(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH APEX1;IDENTIFICATION BY MASS SPECTROMETRY;SUBCELLULAR LOCATION
22.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-63 AND LYS-209;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
23.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-44;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
24.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
25.

"The novel protein MANI modulates neurogenesis and neurite-cone growth."
Mishra M. , Akatsu H. , Heese K.
J. Cell. Mol. Med.15:1713-1725(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FAM168B
26.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
27.

"Crystal structure of a novel human peroxidase enzyme at 2.0-A resolution."
Choi H.-J. , Kang S.W. , Yang C.-H. , Rhee S.G. , Ryu S.-E.
Nat. Struct. Biol.5:400-406(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS)

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