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Index > Protein center > EFNA3(Gene name) > Human
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  • EFNA3 (Gene name),
  • Ephrin-A3 (Protein name ),  EFNA3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    EFNA3(EFL2;EPLG3;LERK3);
    Protein name:
    Ephrin-A3;
    Alternative:
    EHK1 ligand(EHK1-L);EFL-2;EPH-related receptor tyrosine kinase ligand 3(LERK-3);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with EPHA8; activates EPHA8.
    Function:
    Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    238
    Sequence:
    50:
    MAAAPLLLLL | LLVPVPLLPL | LAQGPGGALG | NRHAVYWNSS | NQHLRREGYT | 
    100:
    VQVNVNDYLD | IYCPHYNSSG | VGPGAGPGPG | GGAEQYVLYM | VSRNGYRTCN | 
    150:
    ASQGFKRWEC | NRPHAPHSPI | KFSEKFQRYS | AFSLGYEFHA | GHEYYYISTP | 
    200:
    THNLHWKCLR | MKVFVCCAST | SHSGEKPVPT | LPQFTMGPNV | KINVLEDFEG | 
    238:
    ENPQVPKLEK | SISGTSPKRE | HLPLAVGIAF | FLMTFLAS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    MIM:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Ephrin-A3
    Cat.:
    E0302h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Ephrin-A3
    Cat.:
    E0302m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Ephrin-A3
    Cat.:
    U0302m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Ephrin-A3
    Cat.:
    U0302h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Ephrin-A3
    Cat.:
    P0302Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Ephrin-A3
    Cat.:
    P0302Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Ephrin-A3
    Monoclonal Antibody for Human Ephrin-A3
    Protein for Human Ephrin-A3
    Protein for Human Ephrin-A3

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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Ligands for the receptor tyrosine kinases hek and elk: isolation of cDNAs encoding a family of proteins."
      Kozlosky C.J. , Maraskovsky E. , McGrew J.T. , Vanden Bos T. , Teepe M. , Lyman S.D. , Srinivasan S. , Fletcher F.A. , Gayle R.B. III , Cerretti D.P. , Beckmann M.P.
      Oncogene10:299-306(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity."
      Davis S. , Gale N.W. , Aldrich T.H. , Maisonpierre P.C. , Lhotak V. , Pawson T. , Goldfarb M. , Yancopoulos G.D.
      Science266:816-819(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    4. 4.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
      tissue: Duodenum.
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