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Index > Protein center > Slc8a1(Gene name) > Rat
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  • Slc8a1 (Gene name),
  • Sodium/calcium exchanger 1 (Protein name ),  NAC1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc8a1(Ncx1);
    Protein name:
    Sodium/calcium exchanger 1;
    Alternative:
    Solute carrier family 8 member 1;Na(+)/Ca(2+)-exchange protein 1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    971
    Sequence:
    50:
    MLRLSLPPNV | SMGFRLVTLV | ALLFTHVDHI | TADTEAETGG | NETTECTGSY | 
    100:
    YCKKGVILPI | WEPQDPSFGD | KIARATVYFV | AMVYMFLGVS | IIADRFMSSI | 
    150:
    EVITSQEKEI | TIKKPNGETT | KTTVRIWNET | VSNLTLMALG | SSAPEILLSV | 
    200:
    IEVCGHNFTA | GDLGPSTIVG | SAAFNMFIII | ALCVYVVPDG | ETRKIKHLRV | 
    250:
    FFVTAAWSIF | AYTWLYIILS | VSSPGVVEVW | EGLLTFFFFP | ICVVFAWVAD | 
    300:
    RRLLFYKYVY | KRYRAGKQRG | MIIEHEGDRP | ASKTEIEMDG | KVVNSHVDNF | 
    350:
    LDGALVLEVD | ERDQDDEEAR | REMARILKEL | KQKHPDKEIE | QLIELANYQV | 
    400:
    LSQQQKSRAF | YRIQATRLMT | GAGNILKRHA | ADQARKAVSM | HEVNMDVVEN | 
    450:
    DPVSKVFFEQ | GTYQCLENCG | TVALTIIRRG | GDLTNTVFVD | FRTEDGTANA | 
    500:
    GSDYEFTEGT | VIFKPGETQK | EIRVGIIDDD | IFEEDENFLV | HLSNVRVSSE | 
    550:
    VSEDGILDSN | HVSAIACLGS | PNTATITIFD | DDHAGIFTFE | EPVTHVSESI | 
    600:
    GIMEVKVLRT | SGARGNVIIP | YKTIEGTARG | GGEDFEDTCG | ELEFQNDEIV | 
    650:
    KTISVKVIDD | EEYEKNKTFF | IEIGEPRLVE | MSEKKALLLN | ELGGFTLTEG | 
    700:
    KKMYGQPVFR | KVHARDHPIP | STVISISEEY | DDKQPLTSKE | EEERRIAEMG | 
    750:
    RPILGEHTKL | EVIIEESYEF | KSTVDKLIKK | TNLALVVGTN | SWREQFIEAI | 
    800:
    TVSAGEDDDD | DECGEEKLPS | CFDYVMHFLT | VFWKVLFAFV | PPTEYWNGWA | 
    850:
    CFIVSILMIG | LLTAFIGDLA | SHFGCTIGLK | DSVTAVVFVA | LGTSVPDTFA | 
    900:
    SKVAATQDQY | ADASIGNVTG | SNAVNVFLGI | GVAWSIAAIY | HAANGEQFKV | 
    950:
    SPGTLAFSVT | LFTIFAFINV | GVLLYRRRPE | IGGELGGPRT | AKLLTSSLFV | 
    971:
    LLWLLYIFFS | SLEAYCHIKG | F
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    SMR:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Sodium/calcium exchanger 1
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    E0315h
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    ELISA Kit for Rat Sodium/calcium exchanger 1
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    ELISA Kit for Rat Sodium/calcium exchanger 1
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    ELISA Kit for Rat Sodium/calcium exchanger 1
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    E0315b
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    96T
    ELISA Kit for Rat Sodium/calcium exchanger 1
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    E0315d
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    CLIA Kit for Rat Sodium/calcium exchanger 1
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    U0315r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Sodium/calcium exchanger 1
    Cat.:
    U0315h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Sodium/calcium exchanger 1
    Cat.:
    U0315m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Sodium/calcium exchanger 1
    Cat.:
    U0315d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Sodium/calcium exchanger 1
    Cat.:
    U0315b
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat Sodium/calcium exchanger 1
    Polyclonal Antibody for Rat Sodium/calcium exchanger 1
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    P0315Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Sodium/calcium exchanger 1
    Polyclonal Antibody for Rat Sodium/calcium exchanger 1
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    P0315Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Sodium/calcium exchanger 1
    Cat.:
    P0315Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Sodium/calcium exchanger 1
    Monoclonal Antibody for Rat Sodium/calcium exchanger 1
    Monoclonal Antibody for Rat Sodium/calcium exchanger 1
    Monoclonal Antibody for Rat Sodium/calcium exchanger 1
    Monoclonal Antibody for Rat Sodium/calcium exchanger 1
    Protein for Rat Sodium/calcium exchanger 1
    Protein for Rat Sodium/calcium exchanger 1
    Protein for Rat Sodium/calcium exchanger 1
    Protein for Rat Sodium/calcium exchanger 1
    Protein for Rat Sodium/calcium exchanger 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of the rat heart Na(+)-Ca2+ exchanger and its functional expression in HeLa cells."
      Low W. , Kasir J. , Rahamimoff H.
      FEBS Lett.316:63-67(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Heart.
    2. 2.
      "Cloning of two isoforms of the rat brain Na(+)-Ca2+ exchanger gene and their functional expression in HeLa cells."
      Furman I. , Cook O. , Kasir J. , Rahamimoff H.
      FEBS Lett.319:105-109(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3);ALTERNATIVE SPLICING
      tissue: Brain.
    3. 3.
      "Cloning of the rat aortic smooth muscle Na+/Ca2+ exchanger and tissue-specific expression of isoforms."
      Nakasaki Y. , Iwamoto T. , Hanada H. , Imagawa T. , Shigekawa M.
      J. Biochem.114:528-534(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4);TISSUE SPECIFICITY
      tissue: Aortic smooth muscle.
    4. 4.
      "Tissue-specific expression of Na(+)-Ca2+ exchanger isoforms."
      Lee S.-L. , Yu A.S.L. , Lytton J.
      J. Biol. Chem.269:14849-14852(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4);ALTERNATIVE SPLICING
      strain: Sprague-Dawley.
      tissue: Kidney cortex.
    5. 5.
      "Cloning of mesangial cell Na(+)/Ca(2+) exchangers from Dahl/Rapp salt-sensitive/resistant rats."
      Unlap M.T. , Peti-Peterdi J. , Bell P.D.
      Am. J. Physiol.279:F177-F184(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 4; 5 AND 7);FUNCTION;ENZYME REGULATION
      strain: Dahl salt-resistant.
      strain: Dahl salt-sensitive.
      tissue: Mesangial cell.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6);FUNCTION;ENZYME REGULATION
      strain: Sprague-Dawley.
      tissue: Mesangial cell.
    7. 7.
      "Regional distribution in the rat central nervous system of a mRNA encoding a portion of the cardiac sodium/calcium exchanger isolated from cerebellar granule neurons."
      Marlier L.N.J.-L. , Zheng T. , Tang J. , Grayson D.R.
      Brain Res. Mol. Brain Res.20:21-39(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 750-902;TISSUE SPECIFICITY
      strain: Sprague-Dawley.
      tissue: Neuron.
    8. 8.
      "Identification and localization of renal Na(+)-Ca2+ exchanger by polymerase chain reaction."
      Yu A.S.L. , Hebert S.C. , Lee S.-L. , Brenner B.M. , Lytton J.
      Am. J. Physiol.263:F680-F685(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 780-912;TISSUE SPECIFICITY
      strain: CD Charles River.
      tissue: Kidney.
    9. 9.
      "Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3."
      Nicoll D.A. , Quednau B.D. , Qui Z. , Xia Y.-R. , Lusis A.J. , Philipson K.D.
      J. Biol. Chem.271:24914-24921(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
      strain: Sprague-Dawley.
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