AFP Protein for Human(Homo sapiens) | EIAab.comAFP Protein for Human(Homo sapiens)

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AFP (Gene name),

Alpha-fetoprotein (Protein name ), FETA_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (2)

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Gene name:

AFP(HPAFP);

Protein name:

Alpha-fetoprotein;

Alternative:

Alpha-fetoglobulin;Alpha-1-fetoprotein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Dimeric and trimeric forms have been found in addition to the monomeric form.

Function:

Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

609

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

609:

SKTRAALGV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P02771

MIM:

104150

UniGene:

Hs.518808

STRING:

9606.ENSP00000226359

String:

P02771

KEGG:

hsa:174

Pfam:

PF00273

Uniprot:

P02771

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ELISA Kit for Human Alpha-fetoprotein

Cat.:

E0153m

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96T

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ELISA Kit for Human Alpha-fetoprotein

Cat.:

E0153h

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96T

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ELISA Kit for Human Alpha-fetoprotein

Cat.:

E0153r

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96T

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ELISA Kit for Human Alpha-fetoprotein

Cat.:

E0153b

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96T

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ELISA Kit for Human Alpha-fetoprotein

Cat.:

E0153c

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96T

ELISA Kit for Human Alpha-fetoprotein

Cat.:

E0153d

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96T

ELISA Kit for Human Alpha-fetoprotein

Cat.:

E0153p

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96T

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CLIA Kit for Human Alpha-fetoprotein

Cat.:

U0153p

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96T

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CLIA Kit for Human Alpha-fetoprotein

Cat.:

U0153b

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Packing:

96T

CLIA Kit for Human Alpha-fetoprotein

Cat.:

U0153d

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96T

CLIA Kit for Human Alpha-fetoprotein

Cat.:

U0153r

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96T

CLIA Kit for Human Alpha-fetoprotein

Cat.:

U0153m

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96T

CLIA Kit for Human Alpha-fetoprotein

Cat.:

U0153c

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96T

CLIA Kit for Human Alpha-fetoprotein

Cat.:

U0153h

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96T

Polyclonal Antibody for Human Alpha-fetoprotein

Cat.:

P0153Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Alpha-fetoprotein

Cat.:

P0153Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Alpha-fetoprotein

Cat.:

P0153Rb-m

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40ug/0.2ml

Monoclonal Antibody for Human Alpha-fetoprotein

Protein for Human Alpha-fetoprotein

Cat.:

R0153h

Price:

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Packing:

1mg

Purity:

>90%

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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Citations

[1].

"Multiplex detection of tumor markers with photonic suspension array"

Y Zhao, X Zhao, X Pei , et al.

From:Analytica Chimica Acta

[2].

"Diagnostic Outcomes of Soluble Major Histocompatibility Complex Class I Related Chain Molecule A and Des-γ Carboxy Prothrombin versus Alpha..."

El-Sherif A A S, Eldin A M K, Higazi A, et al.

From:Immunome Research

References

1.

"Primary structures of human alpha-fetoprotein and its mRNA."
Morinaga T. , Sakai M. , Wegmann T.G. , Tamaoki T.
Proc. Natl. Acad. Sci. U.S.A.80:4604-4608(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene."
Gibbs P.E.M. , Zielinski R. , Boyd C. , Dugaiczyk A.
Biochemistry26:1332-1343(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLY-570
tissue: Heart.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
5.

"The human alpha-fetoprotein gene. Sequence organization and the 5' flanking region."
Sakai M. , Morinaga T. , Urano Y. , Watanabe K. , Wegmann T.G. , Tamaoki T.
J. Biol. Chem.260:5055-5060(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28 AND 596-609;GENE STRUCTURE
6.

"A G-->A substitution in an HNF I binding site in the human alpha-fetoprotein gene is associated with hereditary persistence of alpha-fetoprotein (HPAFP)."
McVey J.H. , Michaelides K. , Hansen L.P. , Ferguson-Smith M. , Tilghman S. , Krumlauf R. , Tuddenham E.G.D.
Hum. Mol. Genet.2:379-384(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28
7.

Lubec G. , Vishwanath V.
Submitted (2007-03) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 311-332; 348-372 AND 422-437;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Brain.
tissue: Cajal-Retzius cell.
8.

"Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA."
Beattie W.G. , Dugaiczyk A.
Gene20:415-422(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 429-556
9.

"Human alpha-fetoprotein primary structure: a mass spectrometric study."
Pucci P. , Siciliano R. , Malorni A. , Marino G. , Tecce M.F. , Ceccarini C. , Terrana B.
Biochemistry30:5061-5066(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-609
10.

"Studies on human alpha-fetoprotein. Isolation and characterization of monomeric and polymeric forms and amino-terminal sequence analysis."
Yachnin S. , Hsu R. , Heinrikson R.L. , Miller J.B.
Biochim. Biophys. Acta493:418-428(1977) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY PROTEIN SEQUENCE OF 19-35
11.

"Comparative chemical structures of human alpha-fetoproteins from fetal serum and from ascites fluid of a patient with hepatoma."
Aoyagi Y. , Ikenaka T. , Ichida F.
Cancer Res.37:3663-3667(1977) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY PROTEIN SEQUENCE OF 19-38
12.

"Alpha fetoprotein: structure and expression in man and inbred mouse strains under normal conditions and liver injury."
Ruoslahti E. , Pihko H. , Vaheri A. , Seppala M. , Virolainen M. , Konttinen A.
Johns Hopkins Med. J. Suppl.3:249-255(1974) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY PROTEIN SEQUENCE OF 19-39
13.

"Copper(II)-binding ability of human alpha-fetoprotein."
Aoyagi Y. , Ikenaka T. , Ichida F.
Cancer Res.38:3483-3486(1978) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: METAL-BINDING
14.

"Alpha-fetoprotein as a carrier protein in plasma and its bilirubin-binding ability."
Aoyagi Y. , Ikenaka T. , Ichida F.
Cancer Res.39:3571-3574(1979) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: BILIRUBIN-BINDING
15.

"Tyrosine sulfation of proteins from the human hepatoma cell line HepG2."
Liu M.C. , Yu S. , Sy J. , Redman C.M. , Lipmann F.
Proc. Natl. Acad. Sci. U.S.A.82:7160-7164(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SULFATION
16.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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